Aliases for MDC1-AS1 Gene

Subcategory (RNA class) for MDC1-AS1 Gene

lncRNA

Number of RNA Genes sources:

2 / 17

Aliases for MDC1-AS1 Gene

  • MDC1 Antisense RNA 1 2 3 5
  • MDC1 Antisense RNA 1 (Non-Protein Coding) 2 3
  • MDC1-AS1 2 5
  • MDC1-AS 2 3
  • XXbac-BPG27H4.7 3
  • NONHSAG046589.2 91
  • NONHSAG043427.2 91
  • NONHSAG046409.2 91
  • NONHSAG045701.2 91
  • NONHSAG046228.2 91
  • NONHSAG046074.2 91
  • NONHSAG045891.2 91
  • NONHSAG045580.2 91
  • HSALNG0049184 164
  • HSALNG0049188 164

External Ids for MDC1-AS1 Gene

Previous GeneCards Identifiers for MDC1-AS1 Gene

  • GC00U933522
  • GC06P030673
  • GC06P030704
  • GC06P032281
  • GC06P032471
  • GC06P032581
  • GC06P033368
  • GC06P030842
  • GC06P030830
  • GC06P030905
  • GC06P031064
  • GC06P031209
  • GC06P031416
  • GC06P032056

Summaries for MDC1-AS1 Gene

GeneCards Summary for MDC1-AS1 Gene

MDC1-AS1 (MDC1 Antisense RNA 1) is an RNA Gene, and is affiliated with the lncRNA class. Diseases associated with MDC1-AS1 include Bladder Cancer and Melanoma.

Additional gene information for MDC1-AS1 Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MDC1-AS1 Gene

Genomics for MDC1-AS1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MDC1-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH06J030703 Enhancer 0.4 Ensembl 600.7 +0.7 734 2 ZNF600 POLR2A POLR2B MDC1-AS1 MICD DHX16 CCHCR1 lnc-NRM-2 NRM MDC1 RF00017-5401
GH06J030739 Promoter/Enhancer 2.4 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 10.8 +39.8 39839 6.5 ARHGAP35 CEBPG SP1 HNRNPL CREB1 GATAD2A CTCF ZBTB33 TEAD4 PRDM10 FLOT1 HCG20 IER3 IER3-AS1 lnc-IER3-6 MDC1 LY6G5B DDX39B DHX16 GTF2H4
GH06J030735 Promoter/Enhancer 1.3 Ensembl ENCODE dbSUPER 11.2 +34.0 34043 2.9 BACH1 LARP7 ZNF143 RELA RBFOX2 IKZF2 TRIM22 HDAC1 SOX6 PKNOX1 ENSG00000201988 PTMAP1 ATAT1 MRPS18B PPP1R10 MDC1-AS1 PSORS1C2 C6orf136 DHX16 VARS2
GH06J030730 Enhancer 1.1 ENCODE dbSUPER 11.4 +28.0 28004 1 HNRNPL GATAD2A CTCF ZBTB33 PRDM10 IKZF1 ZNF692 JUND LARP7 MTA2 NONHSAG045583.2 DHX16 C6orf136 MDC1-AS1 HLA-C PPP1R18 FLOT1 piR-52079-179 TUBB RF00017-5401
GH06J030597 Enhancer 1 Ensembl ENCODE 11.1 -104.8 -104816 2.3 CTCF IKZF1 DDX20 ZNF143 PKNOX1 POLR2A REST RAD21 ZNF501 TRIM22 RF00017-5400 MICD ABCF1 PPP1R10 ATAT1 PTMAP1 VARS2 GNL1 PRR3 C6orf136
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MDC1-AS1 on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MDC1-AS1 Gene

Genomic Locations for MDC1-AS1 Gene
chr6:30,703,067-30,713,185
(GRCh38/hg38)
Size:
10,119 bases
Orientation:
Plus strand

Genomic View for MDC1-AS1 Gene

Genes around MDC1-AS1 on UCSC Golden Path with GeneCards custom track
MDC1-AS1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Cytogenetic band:
MDC1-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MDC1-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

Proteins for MDC1-AS1 Gene

Post-translational modifications for MDC1-AS1 Gene

No Post-translational modifications

No data available for DME Specific Peptides for MDC1-AS1 Gene

Domains & Families for MDC1-AS1 Gene

Gene Families for MDC1-AS1 Gene

genes like me logo Genes that share domains with MDC1-AS1: view

No data available for Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MDC1-AS1 Gene

Function for MDC1-AS1 Gene

Phenotypes From GWAS Catalog for MDC1-AS1 Gene

Animal Model Products

CRISPR Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MDC1-AS1 Gene

Localization for MDC1-AS1 Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MDC1-AS1 gene
Compartment Confidence
nucleus 1

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MDC1-AS1 Gene

Pathways & Interactions for MDC1-AS1 Gene

PathCards logo

SuperPathways for MDC1-AS1 Gene

No Data Available

Gene Ontology (GO) - Biological Process for MDC1-AS1 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MDC1-AS1 Gene

Drugs & Compounds for MDC1-AS1 Gene

No Compound Related Data Available

Transcripts for MDC1-AS1 Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MDC1-AS1 Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS0000050C72_9606 lncRNA 738 5

HGNC: 39764,

RefSeq: NR_133647,

Ensembl: ENST00000421805 (view in UCSC) , ENST00000442150 (view in UCSC) , ENST00000442464 (view in UCSC) , ENST00000447707 (view in UCSC) , ENST00000454162 (view in UCSC) ,

LncBook: HSALNT0104036,

NONCODE: NONHSAT108668.2, NONHSAT116412.2, NONHSAT116648.2, NONHSAT116998.2, NONHSAT117349.2,

URS00008C28B4_9606 lncRNA 738 2

Ensembl: ENST00000420050 (view in UCSC) ,

NONCODE: NONHSAT118007.2,

URS0000EB3EE0_9606 lncRNA 741 1

LncBook: HSALNT0289367,

URS00009AF476_9606 lncRNA 738 1

NONCODE: NONHSAT207080.1,

MDC1-AS1 in the GeneCards ncRNA compendium hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MDC1-AS1 Gene

1 NCBI additional mRNA sequence :

CRISPR Products

Alternative Splicing Database (ASD) splice patterns (SP) for MDC1-AS1 Gene

No ASD Table

Relevant External Links for MDC1-AS1 Gene

GeneLoc Exon Structure for
MDC1-AS1

Expression for MDC1-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MDC1-AS1 Gene

genes like me logo Genes that share expression patterns with MDC1-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MDC1-AS1 Gene

Orthologs for MDC1-AS1 Gene

Evolution for MDC1-AS1 Gene

ENSEMBL:
Gene Tree for MDC1-AS1 (if available)
TreeFam:
Gene Tree for MDC1-AS1 (if available)

No data available for Orthologs for MDC1-AS1 Gene

Paralogs for MDC1-AS1 Gene

No data available for Paralogs for MDC1-AS1 Gene

Variants for MDC1-AS1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MDC1-AS1 Gene

SNP ID Clinical significance and condition Chr 06 pos Variation AA Info Type
716887 Benign: not provided 30,712,186(+) A/C MISSENSE_VARIANT
716888 Benign: not provided 30,712,862(+) A/G NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT
725735 Benign: not provided 30,703,429(+) T/C MISSENSE_VARIANT
747196 Likely Benign: not provided 30,704,104(+) C/T SYNONYMOUS_VARIANT
775076 Benign: not provided 30,705,355(+) G/A SYNONYMOUS_VARIANT

Additional dbSNP identifiers (rs#s) for MDC1-AS1 Gene

Additional Variant Information for MDC1-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MDC1-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MDC1-AS1 Gene

Disorders for MDC1-AS1 Gene

MalaCards: The human disease database

(4) MalaCards diseases for MDC1-AS1 Gene - From: LncRNADisease and DISEASES

Disorder Aliases PubMed IDs
bladder cancer
  • bladder cancer, somatic
melanoma
  • malignant melanoma
malignant glioma
  • glial cell tumor
gastric cancer
  • gastric cancer, somatic
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MDC1-AS1

genes like me logo Genes that share disorders with MDC1-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MDC1-AS1 Gene

Publications for MDC1-AS1 Gene

  1. MDC1-AS, an antisense long noncoding RNA, regulates cell proliferation of glioma. (PMID: 27261595) Yue H … Xu Q (Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2016) 2 3
  2. A novel antisense long noncoding RNA regulates the expression of MDC1 in bladder cancer. (PMID: 25514464) Xue Y … Wang M (Oncotarget 2015) 2 3

Products for MDC1-AS1 Gene

Sources for MDC1-AS1 Gene