Aliases for MCAT Gene
- Malonyl-CoA-Acyl Carrier Protein Transacylase 2 3 5
- Malonyl-CoA-Acyl Carrier Protein Transacylase, Mitochondrial 3 4
- Malonyl CoA:ACP Acyltransferase (Mitochondrial) 2 3
- Mitochondrial Malonyl CoA:ACP Acyltransferase 3 4
- [Acyl-Carrier-Protein] S-Malonyltransferase 2 3
- [Acyl-Carrier-Protein] Malonyltransferase 3 4
- Mitochondrial Malonyltransferase 3 4
External Ids for MCAT Gene
Previous GeneCards Identifiers for MCAT Gene
The protein encoded by this gene is found exclusively in the mitochondrion, where it catalyzes the transfer of a malonyl group from malonyl-CoA to the mitochondrial acyl carrier protein. The encoded protein may be part of a fatty acid synthase complex that is more like the type II prokaryotic and plastid complexes rather than the type I human cytosolic complex. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Mar 2012]
GeneCards Summary for MCAT Gene
MCAT (Malonyl-CoA-Acyl Carrier Protein Transacylase) is a Protein Coding gene. Diseases associated with MCAT include Chronic Purulent Otitis Media and Middle Ear Disease. Among its related pathways are Metabolism and Fatty Acyl-CoA Biosynthesis. Gene Ontology (GO) annotations related to this gene include [acyl-carrier-protein] S-malonyltransferase activity.
UniProtKB/Swiss-Prot Summary for MCAT Gene
Catalyzes the transfer of a malonyl moiety from malonyl-CoA to the free thiol group of the phosphopantetheine arm of the mitochondrial ACP protein (NDUFAB1). This suggests the existence of the biosynthesis of fatty acids in mitochondria.