Aliases for MBD3L2B Gene

Aliases for MBD3L2B Gene

  • Methyl-CpG Binding Domain Protein 3 Like 2B 2 3 5
  • Methyl-CpG-Binding Domain Protein 3-Like 2B 3 4

External Ids for MBD3L2B Gene

Summaries for MBD3L2B Gene

GeneCards Summary for MBD3L2B Gene

MBD3L2B (Methyl-CpG Binding Domain Protein 3 Like 2B) is a Protein Coding gene. An important paralog of this gene is MBD3L2.

Additional gene information for MBD3L2B Gene

No data available for Entrez Gene Summary , CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MBD3L2B Gene

Genomics for MBD3L2B Gene

GeneHancer (GH) Regulatory Elements for MBD3L2B Gene

Promoters and enhancers for MBD3L2B Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH19J007021 Promoter 0.3 EPDnew 500.7 0.0 -35 0.1 MBD3L2B lnc-MBD3L4-1 MBD3L5
GH19J007028 Enhancer 0.2 Ensembl 0.4 -7.4 -7351 0.8 MBD3L5 MBD3L2B
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MBD3L2B on UCSC Golden Path with GeneCards custom track

Genomic Locations for MBD3L2B Gene

Genomic Locations for MBD3L2B Gene
2,482 bases
Minus strand
2,271 bases
Minus strand

Genomic View for MBD3L2B Gene

Genes around MBD3L2B on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MBD3L2B Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MBD3L2B Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MBD3L2B Gene

Proteins for MBD3L2B Gene

  • Protein details for MBD3L2B Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    Methyl-CpG-binding domain protein 3-like 2B
    Protein Accession:

    Protein attributes for MBD3L2B Gene

    204 amino acids
    Molecular mass:
    22665 Da
    Quaternary structure:
    No Data Available
    • The MBD3L proteins are encoded by strongly repeated regions of the 19p13 chromosome. The exact number of functional copies is unclear, and some of them may represent pseudogenes.

neXtProt entry for MBD3L2B Gene

Post-translational modifications for MBD3L2B Gene

No Post-translational modifications

Other Protein References for MBD3L2B Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MBD3L2B Gene

Domains & Families for MBD3L2B Gene

Gene Families for MBD3L2B Gene

Human Protein Atlas (HPA):
  • Predicted intracellular proteins

Protein Domains for MBD3L2B Gene

Graphical View of Domain Structure for InterPro Entry



  • Belongs to the MBD3L family.
  • Belongs to the MBD3L family.
genes like me logo Genes that share domains with MBD3L2B: view

No data available for Suggested Antigen Peptide Sequences for MBD3L2B Gene

Function for MBD3L2B Gene

Gene Ontology (GO) - Molecular Function for MBD3L2B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008327 methyl-CpG binding IBA 21873635
genes like me logo Genes that share ontologies with MBD3L2B: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MBD3L2B Gene

Localization for MBD3L2B Gene

Gene Ontology (GO) - Cellular Components for MBD3L2B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IBA 21873635
genes like me logo Genes that share ontologies with MBD3L2B: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS and Subcellular locations from the Human Protein Atlas (HPA) for MBD3L2B Gene

Pathways & Interactions for MBD3L2B Gene

PathCards logo

SuperPathways for MBD3L2B Gene

No Data Available

Interacting Proteins for MBD3L2B Gene


Gene Ontology (GO) - Biological Process for MBD3L2B Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000122 negative regulation of transcription by RNA polymerase II IBA 21873635
GO:0006346 methylation-dependent chromatin silencing IBA 21873635
genes like me logo Genes that share ontologies with MBD3L2B: view

No data available for Pathways by source and SIGNOR curated interactions for MBD3L2B Gene

Drugs & Compounds for MBD3L2B Gene

No Compound Related Data Available

Transcripts for MBD3L2B Gene

mRNA/cDNA for MBD3L2B Gene

2 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for MBD3L2B Gene

No ASD Table

Relevant External Links for MBD3L2B Gene

GeneLoc Exon Structure for

Expression for MBD3L2B Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MBD3L2B Gene

Orthologs for MBD3L2B Gene

This gene was present in the common ancestor of mammals.

Orthologs for MBD3L2B Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia MBD3L2 30
  • 98.2 (n)
(Canis familiaris)
Mammalia LOC100688619 30
  • 66.67 (n)
(Bos Taurus)
Mammalia MBD3L3 30
  • 62.96 (n)
(Rattus norvegicus)
Mammalia Mbd3l2 30
  • 57.31 (n)
(Mus musculus)
Mammalia Mbd3l2 30
  • 56.81 (n)
Species where no ortholog for MBD3L2B was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • oppossum (Monodelphis domestica)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • platypus (Ornithorhynchus anatinus)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)
  • zebrafish (Danio rerio)

Evolution for MBD3L2B Gene

Gene Tree for MBD3L2B (if available)
Gene Tree for MBD3L2B (if available)

Paralogs for MBD3L2B Gene

Paralogs for MBD3L2B Gene

genes like me logo Genes that share paralogs with MBD3L2B: view

Variants for MBD3L2B Gene

Additional dbSNP identifiers (rs#s) for MBD3L2B Gene

Additional Variant Information for MBD3L2B Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) and Variation tolerance for MBD3L2B Gene

Disorders for MBD3L2B Gene

Additional Disease Information for MBD3L2B

No disorders were found for MBD3L2B Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MBD3L2B Gene

Publications for MBD3L2B Gene

  1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. (PMID: 21873635) Gaudet P … Thomas PD (Briefings in bioinformatics 2011) 3 54
  2. The DNA sequence and biology of human chromosome 19. (PMID: 15057824) Grimwood J … Lucas SM (Nature 2004) 4 54

No data available for Mastermind for MBD3L2B Gene

Products for MBD3L2B Gene

Sources for MBD3L2B Gene