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This gene encodes a member of the globin superfamily and is predominantly expressed in skeletal and cardiac muscles. The encoded protein forms a monomeric globular haemoprotein that is primarily responsible for the storage and facilitated transfer of oxygen from the cell membrane to the mitochondria. This protein also plays a role in regulating physiological levels of nitric ox... See more...
Aliases for MB Gene
External Ids for MB Gene
- HGNC: 6915
- Entrez Gene: 4151
- Ensembl: ENSG00000198125
- OMIM: 160000
- UniProtKB: P02144
Previous GeneCards Identifiers for MB Gene
- GC22M032646
- GC22M034274
- GC22M034327
- GC22M036002
- GC22M018967
Summaries for MB Gene
-
This gene encodes a member of the globin superfamily and is predominantly expressed in skeletal and cardiac muscles. The encoded protein forms a monomeric globular haemoprotein that is primarily responsible for the storage and facilitated transfer of oxygen from the cell membrane to the mitochondria. This protein also plays a role in regulating physiological levels of nitric oxide. Multiple transcript variants encoding distinct isoforms exist for this gene. [provided by RefSeq, May 2020]
GeneCards Summary for MB Gene
MB (Myoglobin) is a Protein Coding gene. Diseases associated with MB include Compartment Syndrome and Medullomyoblastoma. Among its related pathways are Effects of Nitric Oxide and Glucose / Energy Metabolism. Gene Ontology (GO) annotations related to this gene include iron ion binding and oxygen binding. An important paralog of this gene is CYGB.
UniProtKB/Swiss-Prot Summary for MB Gene
-
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
Additional gene information for MB Gene
- HGNC(6915)
- Entrez Gene(4151)
- Ensembl(ENSG00000198125)
- OMIM(160000)
- UniProtKB(P02144)
- Open Targets Platform(ENSG00000198125)
- Search for MB at DataMed
- Search for MB at HumanCyc
No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MB Gene
Genomics for MB Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for MB Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around MB on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for MB
- Top Transcription factor binding sites by QIAGEN in the MB gene promoter:
-
- AP-1
- MyoD
Genomic Locations for MB Gene
Genomic Locations for MB Gene
- chr22:35,606,764-35,637,951
- (GRCh38/hg38)
- Size:
- 31,188 bases
- Orientation:
- Minus strand
- chr22:36,002,811-36,033,998
- (GRCh37/hg19)
- Size:
- 31,188 bases
- Orientation:
- Minus strand
Genomic View for MB Gene
Genes around MB on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 22q12.3 by HGNC
- 22q12.3 by Entrez Gene
- 22q12.3 by Ensembl
MB Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MB Gene
Proteins for MB Gene
-
Protein details for MB Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P02144-MYG_HUMAN
- Recommended name:
- Myoglobin
- Protein Accession:
- P02144
- Q52H51
- Q5THY7
Protein attributes for MB Gene
- Size:
- 154 amino acids
- Molecular mass:
- 17184 Da
- Quaternary structure:
- No Data Available
Protein Expression for MB Gene
Post-translational modifications for MB Gene
Other Protein References for MB Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for MB
-
Abcam antibodies for MB
- Invitrogen Antibodies for MB (AFLGC-MB)
- antibodies-online: Show 187 available MB Antibodies ranked by validation data
- Compare Top MB Antibodies
-
Recommended
- 129 WB Antibodies (anti-human)
- 14 IHC (p) Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 11 IHC Antibodies (anti-human)
- 5 RIA Antibodies (anti-human)
- 4 IP Antibodies (anti-human)
- 4 LF Antibodies (anti-human)
- 4 TIA Antibodies (anti-human)
- 3 EIA Antibodies (anti-human)
- 2 FACS Antibodies (anti-human)
- 2 TB Antibodies (anti-human)
- 1 IEP Antibody (anti-human)
- 1 IT Antibody (anti-human)
- 39 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 4 IP Antibodies (anti-rat)
- 3 IHC (p) Antibodies (anti-rat)
- 2 RIA Antibodies (anti-rat)
- 51 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 3 IHC (p) Antibodies (anti-mouse)
- 2 RIA Antibodies (anti-mouse)
-
Santa Cruz Biotechnology (SCBT) Antibodies for MB
- Sino Biological Antibodies for MB
Protein Products
- G Biosciences Human Myoglobin/MB, Liquid
- Search Origene for MassSpec and Protein Over-expression Lysates for MB
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- ProSpec Recombinant Proteins for MB
- antibodies-online: Show 145 available MB Proteins ranked by validation data
- Compare Top MB Proteins
-
Abcam proteins for MB
Assay Products
- G Biosciences Immunotag™ Myoglobin ELISA Kit
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-
Custom Assay ServicesOriGene ELISA Kits for MB
- Novus Biologicals ELISA Kits for MB
- antibodies-online: Show 114 available MB Elisa Kits ranked by validation data
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-
Quality Products:
- ABIN1116090
- ABIN366712
- ABIN1029350
- ABIN4883846
- ABIN1326866
- ABIN5668664
- ABIN770997
- ABIN455945
- ABIN6384842
- ABIN5657071
- ABIN1116089
- ABIN367795
- ABIN492000
- ABIN5564582
- ABIN5669857
- ABIN1029351
- ABIN773460
- ABIN5657073
- ABIN5657074
- ABIN5608932
- ABIN6720458
- ABIN1116091
- ABIN368184
- ABIN492002
- ABIN5670517
- ABIN1571404
- ABIN772117
- ABIN5657079
- ABIN5657078
- ABIN5608933
- ABIN364700
- ABIN994035
- ABIN6206157
- ABIN956102
- ABIN780263
- ABIN1143584
-
Signalway ELISA kits for MB
-
Abcam assays for MB
No data available for DME Specific Peptides for MB Gene
Domains & Families for MB Gene
Gene Families for MB Gene
- Human Protein Atlas (HPA):
-
- Candidate cardiovascular disease genes
- Plasma proteins
- Predicted intracellular proteins
- Transporters
Protein Domains for MB Gene
- InterPro:
- Blocks:
-
- Myoglobin signature
- ProtoNet:
Suggested Antigen Peptide Sequences for MB Gene
- GenScript: Design optimal peptide antigens:
-
- cDNA FLJ55163, highly similar to Myoglobin (B4DUI1_HUMAN)
- Myoglobin (MYG_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P02144- Family:
-
- Belongs to the globin family.
Function for MB Gene
Molecular function for MB Gene
- UniProtKB/Swiss-Prot Function:
- Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
- GENATLAS Biochemistry:
- myoglobin,17.5kDa,muscle oxygen-carrying hemoprotein,non covalently
Phenotypes From GWAS Catalog for MB Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005344 | oxygen carrier activity | IEA | -- |
| GO:0019825 | oxygen binding | IEA,IBA | 21873635 |
| GO:0020037 | heme binding | IEA | -- |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for MB Gene
- MGI mutant phenotypes for MB:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for MB:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for MB - Select products 50% OFF >
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Santa Cruz Biotechnology (SCBT) CRISPR for MB
miRNA for MB Gene
- miRTarBase miRNAs that target MB
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MB
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Clone Products
- Applied Biological Materials (abm): Clones for MB - Select products 50% OFF >
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-
- MG201129
- MG215219
- MG215299
- MR201129
- MR201129L3
- MR201129L4
- MR215219
- MR215219L3
- MR215219L4
- MR215299
- MR215299L3
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- RC203113
- RC203113L3
- RC203113L4
- RC212352
- RC212352L1
- RC212352L2
- RC212352L3
- RC212352L4
- RC213272
- RC213272L3
- RC213272L4
- RG203113
- RG212352
- RG213272
- RR212944
- RR212944L3
- RR212944L4
- MR201129L3V
- MR201129L4V
- MR215219L3V
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- RR212944L3V
- RR212944L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for MB
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MB
Cell Line Products
-
Horizon Cell Lines for MB
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for MB Gene
Localization for MB Gene
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| cytosol | 5 |
| cytoskeleton | 3 |
| mitochondrion | 3 |
| plasma membrane | 2 |
| nucleus | 2 |
| endoplasmic reticulum | 2 |
| lysosome | 2 |
| peroxisome | 1 |
| endosome | 1 |
| golgi apparatus | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005829 | cytosol | TAS | -- |
| GO:0070062 | extracellular exosome | HDA | 23533145 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for MB Gene
Pathways & Interactions for MB Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Glucose / Energy Metabolism | ||
| 2 | Effects of Nitric Oxide | ||
Pathways by source for MB Gene
1 BioSystems pathway for MB Gene
1 Cell Signaling Technology pathway for MB Gene
Interacting Proteins for MB Gene
GPS-Prot Interaction Network for MB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001666 | response to hypoxia | IEA | -- |
| GO:0007507 | heart development | IEA | -- |
| GO:0009725 | response to hormone | IEA | -- |
| GO:0015671 | oxygen transport | TAS | -- |
| GO:0031444 | slow-twitch skeletal muscle fiber contraction | IEA | -- |
No data available for SIGNOR curated interactions for MB Gene
Drugs & Compounds for MB Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Oxygen | Approved, Vet_approved | Pharma | 0 | |||
| Carbon monoxide | Approved, Investigational | Pharma | Target, deoxidizer | 171 | ||
| Nitrous acid | Approved, Investigational | Pharma | Target, oxidizer | 0 | ||
| Imidazole | Experimental, Investigational | Pharma | Target | 66 | ||
| 1-Methylimidazole | Experimental | Pharma | Target | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Drug Products
- G Biosciences Human Myoglobin/MB, Liquid
Transcripts for MB Gene
mRNA/cDNA for MB Gene
- 9 REFSEQ mRNAs :
- 25 NCBI additional mRNA sequence :
- 10 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000359787 1170 nts (view in UCSC)
- ENST00000397326 1070 nts (view in UCSC)
- ENST00000397328 1153 nts (view in UCSC)
- ENST00000401702 1043 nts (view in UCSC)
- ENST00000406324 582 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for MB - Select products 50% OFF >
- * MB CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for MB
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MB
-
Santa Cruz Biotechnology (SCBT) CRISPR for MB
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MB
- Browse OriGene Inhibitory RNA Products For MB
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MB
Clone Products
- Applied Biological Materials (abm): Clones for MB - Select products 50% OFF >
- * MB as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
- MG201129
- MG215219
- MG215299
- MR201129
- MR201129L3
- MR201129L4
- MR215219
- MR215219L3
- MR215219L4
- MR215299
- MR215299L3
- MR215299L4
- RC203113
- RC203113L3
- RC203113L4
- RC212352
- RC212352L1
- RC212352L2
- RC212352L3
- RC212352L4
- RC213272
- RC213272L3
- RC213272L4
- RG203113
- RG212352
- RG213272
- RR212944
- RR212944L3
- RR212944L4
- MR201129L3V
- MR201129L4V
- MR215219L3V
- MR215219L4V
- MR215299L3V
- MR215299L4V
- RC203113L3V
- RC203113L4V
- RC212352L1V
- RC212352L2V
- RC212352L3V
- RC212352L4V
- RC213272L3V
- RC213272L4V
- RR212944L3V
- RR212944L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for MB
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MB
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | · | 8c | · | 8d | · | 8e | · | 8f | · | 8g |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | |||||||||||||||||||||||||||||
| SP4: | - | - | - | ||||||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||||||||
| SP6: | - | - | |||||||||||||||||||||||||||||||||
| SP7: | - |
Relevant External Links for MB Gene
- GeneLoc Exon Structure for
- MB
Expression for MB Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Adipose (Muscoskeletal System)
- Skeletal Muscle (Muscoskeletal System)
-
Thyroid (Endocrine System)
-
Heart (Cardiovascular System)
mRNA differential expression in normal tissues according to GTEx for MB Gene
This gene is overexpressed in Muscle - Skeletal (x23.8), Heart - Left Ventricle (x17.4), and Heart - Atrial Appendage (x10.9).
This gene is overexpressed in Tonsil (42.8), Heart (11.3), and Oral epithelium (8.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MB Gene
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MB
SOURCE GeneReport for Unigene cluster for MB Gene:
Hs.517586Evidence on tissue expression from TISSUES for MB Gene
- Heart(5)
- Muscle(5)
- Nervous system(3.3)
- Blood(3.2)
- Kidney(3)
- Liver(3)
- Urine(3)
- Skin(2.8)
- Intestine(2.7)
- Thyroid gland(2.7)
- Lung(2.6)
- Eye(2.2)
- Gall bladder(2.1)
- Bone(2.1)
- Adrenal gland(2.1)
Primer Products
-
OriGene qPCR primer pairs for MB
-
OriGene qPCR primer pairs and template standards for MB
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MB Gene
Orthologs for MB Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | MB 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | MB 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | MB 30 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | MB 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Mb 30 |
|
||
| Mouse (Mus musculus) |
Mammalia | Mb 30 17 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | MB 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | MB 31 |
|
OneToOne | |
| Zebrafish (Danio rerio) |
Actinopterygii | mb 30 31 |
|
OneToOne |
- Species where no ortholog for MB was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Oppossum (Monodelphis domestica)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Squirt (Ciona savignyi)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Tropical Clawed Frog (Silurana tropicalis)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for MB Gene
- ENSEMBL:
- Gene Tree for MB (if available)
- TreeFam:
- Gene Tree for MB (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for MB: view image
Paralogs for MB Gene
Paralogs for MB Gene
(5) SIMAP similar genes for MB Gene using alignment to 10 proteins:
- MYG_HUMAN
- B0QYF7_HUMAN
- B0QYF8_HUMAN
- F2Z2F1_HUMAN
- F2Z337_HUMAN
- Q8WVH6_HUMAN
- U6FIU7_HUMAN
- U6FIV2_HUMAN
- U6FJG6_HUMAN
- U6FM64_HUMAN
Variants for MB Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MB Gene
| SNP ID | Clinical significance and condition | Chr 22 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| 617634 | Pathogenic: myoglobinopathy | 35,610,910(-) | G/A | MISSENSE_VARIANT | |
| rs142225854 | - | p.Arg140Gln | |||
| rs145465287 | - | p.Glu55Lys | |||
| rs766095327 | - | p.Lys134Asn | |||
| rs767663245 | - | p.Arg140Trp |
Residual Variation Intolerance Score:
36.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.34;
7.52% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MB Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MB Gene
Disorders for MB Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| compartment syndrome |
|
|
| medullomyoblastoma |
|
|
| malignant triton tumor |
|
|
| acute kidney tubular necrosis |
|
|
| malignant mesenchymoma |
|
|
Search MB in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for MB
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for MB Gene
Publications for MB Gene
- The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I … O'Brien KP (Nature 1999) 2 3 4
- Cloning of the human myoglobin gene. (PMID: 2989088) Akaboshi E (Gene 1985) 2 3 4
- Expression and functional regulation of myoglobin in epithelial cancers. (PMID: 19541931) Flonta SE … Bardelli A (The American journal of pathology 2009) 3 23
- Strong iron demand during hypoxia-induced erythropoiesis is associated with down-regulation of iron-related proteins and myoglobin in human skeletal muscle. (PMID: 17311997) Robach P … Lundby C (Blood 2007) 3 23
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4
ExternalLinks
Products for MB Gene
- Custom Antibody ServicesOriGene Antibodies for MB
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- Search Origene for MassSpec and Protein Over-expression Lysates for MB
- Origene Custom Protein Services for MB
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MB
- Browse OriGene Inhibitory RNA Products For MB
- OriGene qPCR primer pairs for MB
- OriGene qPCR primer pairs and template standards for MB
- OriGene CRISPR knockouts for MB
- MG201129
- MG215219
- MG215299
- MR201129
- MR201129L3
- MR201129L4
- MR215219
- MR215219L3
- MR215219L4
- MR215299
- MR215299L3
- MR215299L4
- RC203113
- RC203113L3
- RC203113L4
- RC212352
- RC212352L1
- RC212352L2
- RC212352L3
- RC212352L4
- RC213272
- RC213272L3
- RC213272L4
- RG203113
- RG212352
- RG213272
- RR212944
- RR212944L3
- RR212944L4
- MR201129L3V
- MR201129L4V
- MR215219L3V
- MR215219L4V
- MR215299L3V
- MR215299L4V
- RC203113L3V
- RC203113L4V
- RC212352L1V
- RC212352L2V
- RC212352L3V
- RC212352L4V
- RC213272L3V
- RC213272L4V
- RR212944L3V
- RR212944L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MB
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- Browse Sino Biological Recombinant Proteins
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- Sino Biological Antibodies for MB
- Browse Sino Biological Assays
- Browse Antibodies
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- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for MB
- Novus Biologicals proteins and lysates for MB
- Novus Biologicals ELISA Kits for MB
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for MB
- Abcam proteins for MB
- Abcam assays for MB
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- VectorBuilder Custom and pre-made DNA vectors for MB (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for MB (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for MB (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for MB CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for MB
- antibodies-online: Show 187 available MB Antibodies ranked by validation data
- Compare Top MB Antibodies
- Recommended
- 129 WB Antibodies (anti-human)
- 14 IHC (p) Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 11 IHC Antibodies (anti-human)
- 5 RIA Antibodies (anti-human)
- 4 IP Antibodies (anti-human)
- 4 LF Antibodies (anti-human)
- 4 TIA Antibodies (anti-human)
- 3 EIA Antibodies (anti-human)
- 2 FACS Antibodies (anti-human)
- 2 TB Antibodies (anti-human)
- 1 IEP Antibody (anti-human)
- 1 IT Antibody (anti-human)
- 39 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 4 IP Antibodies (anti-rat)
- 3 IHC (p) Antibodies (anti-rat)
- 2 RIA Antibodies (anti-rat)
- 51 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 3 IHC (p) Antibodies (anti-mouse)
- 2 RIA Antibodies (anti-mouse)
- antibodies-online: Show 114 available MB Elisa Kits ranked by validation data
- Compare Top MB Elisa Kits
- Quality Products:
- ABIN1116090
- ABIN366712
- ABIN1029350
- ABIN4883846
- ABIN1326866
- ABIN5668664
- ABIN770997
- ABIN455945
- ABIN6384842
- ABIN5657071
- ABIN1116089
- ABIN367795
- ABIN492000
- ABIN5564582
- ABIN5669857
- ABIN1029351
- ABIN773460
- ABIN5657073
- ABIN5657074
- ABIN5608932
- ABIN6720458
- ABIN1116091
- ABIN368184
- ABIN492002
- ABIN5670517
- ABIN1571404
- ABIN772117
- ABIN5657079
- ABIN5657078
- ABIN5608933
- ABIN364700
- ABIN994035
- ABIN6206157
- ABIN956102
- ABIN780263
- ABIN1143584
- antibodies-online: Show 145 available MB Proteins ranked by validation data
- Compare Top MB Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for MB
- Search Santa Cruz Biotechnology (SCBT) for MB siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for MB
- Horizon Cell Lines for MB
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MB
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MB
- Search GeneCopoeia for miRNA 3'UTR Target clone products for MB
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MB
Sources for MB Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB