External Ids for MB Gene
Previous GeneCards Identifiers for MB Gene
This gene encodes a member of the globin superfamily and is predominantly expressed in skeletal and cardiac muscles. The encoded protein forms a monomeric globular haemoprotein that is primarily responsible for the storage and facilitated transfer of oxygen from the cell membrane to the mitochondria. This protein also plays a role in regulating physiological levels of nitric oxide. Multiple transcript variants encoding distinct isoforms exist for this gene. [provided by RefSeq, May 2020]
GeneCards Summary for MB Gene
MB (Myoglobin) is a Protein Coding gene. Diseases associated with MB include Compartment Syndrome and Medullomyoblastoma. Among its related pathways are Effects of Nitric Oxide and Glucose / Energy Metabolism. Gene Ontology (GO) annotations related to this gene include iron ion binding and oxygen binding. An important paralog of this gene is CYGB.
UniProtKB/Swiss-Prot Summary for MB Gene
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.