Aliases for MB Gene
External Ids for MB Gene
- HGNC: 6915
- Entrez Gene: 4151
- Ensembl: ENSG00000198125
- OMIM: 160000
- UniProtKB: P02144
Previous GeneCards Identifiers for MB Gene
- GC22M032646
- GC22M034274
- GC22M034327
- GC22M036002
- GC22M018967
Summaries for MB Gene
-
This gene encodes a member of the globin superfamily and is expressed in skeletal and cardiac muscles. The encoded protein is a haemoprotein contributing to intracellular oxygen storage and transcellular facilitated diffusion of oxygen. At least three alternatively spliced transcript variants encoding the same protein have been reported. [provided by RefSeq, Jul 2008]
GeneCards Summary for MB Gene
MB (Myoglobin) is a Protein Coding gene. Diseases associated with MB include Compartment Syndrome and Medullomyoblastoma. Among its related pathways are Effects of Nitric Oxide and Glucose / Energy Metabolism. Gene Ontology (GO) annotations related to this gene include iron ion binding and oxygen binding. An important paralog of this gene is CYGB.
UniProtKB/Swiss-Prot for MB Gene
-
Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
No data available for CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MB Gene
Genomics for MB Gene
GeneHancer (GH) Regulatory Elements for MB Gene
Promoters and enhancers for MB Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH22J035637 | Enhancer | 0.9 | Ensembl ENCODE dbSUPER | 650.7 | -0.3 | -265 | 2 | SP1 POLR2A RCOR1 REST RAD21 CHD2 NR2F2 | MB LOC284912 APOL6 | |
| GH22J035617 | Promoter/Enhancer | 0.7 | EPDnew dbSUPER | 650.3 | +20.6 | 20602 | 0.1 | MB ENSG00000268818 RASD2 | ||
| GH22J035639 | Enhancer | 0.3 | dbSUPER | 650.7 | -1.7 | -1684 | 0.3 | ATF2 | MB LOC284912 APOL6 | |
| GH22J035834 | Promoter/Enhancer | 2.2 | EPDnew Ensembl ENCODE dbSUPER | 10.6 | -199.8 | -199807 | 7.4 | PKNOX1 FOXA2 SIN3A FEZF1 ZNF2 YY1 ZNF143 KLF13 SP3 ZNF662 | RBFOX2 GC22M035839 PIR58099 RPL41P3 HMGXB4 EIF3D MCM5 IFT27 APOL6 MB | |
| GH22J035601 | Enhancer | 1.4 | FANTOM5 Ensembl ENCODE dbSUPER | 13.5 | +32.2 | 32185 | 7.7 | ZSCAN4 RFX5 ZNF766 RCOR1 FOS ATF7 CREM EGR2 YY2 USF2 | HMGXB4 APOL6 MCM5 EIF3D MB RASD2 RPS15AP38 TOM1 HMOX1 ENSG00000268818 |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around MB on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the MB gene promoter:
-
- AP-1
- MyoD
Regulatory Element Products
Genomic Locations for MB Gene
Genomic Locations for MB Gene
- chr22:35,606,764-35,637,951
- (GRCh38/hg38)
- Size:
- 31,188 bases
- Orientation:
- Minus strand
- chr22:36,002,811-36,033,998
- (GRCh37/hg19)
- Size:
- 31,188 bases
- Orientation:
- Minus strand
Genomic View for MB Gene
Genes around MB on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 22q12.3 by Entrez Gene
- 22q12.3 by HGNC
- 22q12.3 by Ensembl
MB Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for MB Gene
Proteins for MB Gene
-
Protein details for MB Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P02144-MYG_HUMAN
- Recommended name:
- Myoglobin
- Protein Accession:
- P02144
- Q52H51
- Q5THY7
Protein attributes for MB Gene
- Size:
- 154 amino acids
- Molecular mass:
- 17184 Da
- Quaternary structure:
- No Data Available
Protein Expression for MB Gene
Post-translational modifications for MB Gene
Other Protein References for MB Gene
Antibody Products
- R&D Systems Antibodies for MB (Myoglobin)
- Novus Biologicals Antibodies for MB
-
Abcam antibodies for MB
- Invitrogen Antibodies for MB (AFLGC-MB)
- antibodies-online: Search results for 433 available MB Antibodies ranked by validation data
- Compare Top MB Antibodies
-
Recommended
- 168 WB Antibodies (anti-human)
- 16 IHC (p) Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 11 IHC Antibodies (anti-human)
- 6 RIA Antibodies (anti-human)
- 4 EIA Antibodies (anti-human)
- 4 LF Antibodies (anti-human)
- 2 FACS Antibodies (anti-human)
- 2 IP Antibodies (anti-human)
- 2 TB Antibodies (anti-human)
- 1 IEP Antibody (anti-human)
- 1 IT Antibody (anti-human)
- 29 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 2 IP Antibodies (anti-rat)
- 2 RIA Antibodies (anti-rat)
- 36 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 2 RIA Antibodies (anti-mouse)
- 168 WB Antibodies (anti-human)
- 16 IHC (p) Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 11 IHC Antibodies (anti-human)
- 6 RIA Antibodies (anti-human)
- 4 EIA Antibodies (anti-human)
- 4 LF Antibodies (anti-human)
- 2 FACS Antibodies (anti-human)
- 2 IP Antibodies (anti-human)
- 2 TB Antibodies (anti-human)
- 1 IEP Antibody (anti-human)
- 1 IT Antibody (anti-human)
- 29 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 2 IP Antibodies (anti-rat)
- 2 RIA Antibodies (anti-rat)
- 36 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 2 RIA Antibodies (anti-mouse)
- GeneTex MB Antibody for MB
-
Santa Cruz Biotechnology (SCBT) Antibodies for MB
Protein Products
- Search Origene for MassSpec and Protein Over-expression Lysates for MB
- Origene Custom Protein Services for MB
- Search GeneTex for Proteins for MB
-
Abcam proteins for MB
Assay Products
-
Custom Assay ServicesOriGene ELISA Kits for MB
- R&D Systems Luminex Assays and other biochemical assays for MB (Myoglobin)
- Novus Biologicals ELISA Kits for MB
- antibodies-online: Search results for 102 available MB Elisa Kits ranked by validation data
- Compare Top MB Elisa Kits
-
Recommended
- 3 Chicken ELISA Kits
- 3 Cow (Bovine) ELISA Kits
- 5 Dog (Canine) ELISA Kits
- 1 Goat ELISA Kit
- 5 Guinea Pig ELISA Kits
- 1 Horse (Equine) ELISA Kit
- 22 Human ELISA Kits
- 5 Monkey ELISA Kits
- 16 Mouse (Murine) ELISA Kits
- 14 Pig (Porcine) ELISA Kits
- 10 Rabbit ELISA Kits
- 14 Rat (Rattus) ELISA Kits
- 2 Sheep (Ovine) ELISA Kits
- 2 Wild boar (Sus scrofa) ELISA Kits
- 3 Chicken ELISA Kits
- 3 Cow (Bovine) ELISA Kits
- 5 Dog (Canine) ELISA Kits
- 1 Goat ELISA Kit
- 5 Guinea Pig ELISA Kits
- 1 Horse (Equine) ELISA Kit
- 22 Human ELISA Kits
- 5 Monkey ELISA Kits
- 16 Mouse (Murine) ELISA Kits
- 14 Pig (Porcine) ELISA Kits
- 10 Rabbit ELISA Kits
- 14 Rat (Rattus) ELISA Kits
- 2 Sheep (Ovine) ELISA Kits
- 2 Wild boar (Sus scrofa) ELISA Kits
-
Boster Bio ELISA Kits for MB
-
Abcam assays for MB
No data available for DME Specific Peptides for MB Gene
Domains & Families for MB Gene
Gene Families for MB Gene
- Human Protein Atlas (HPA):
-
- Candidate cardiovascular disease genes
- Plasma proteins
- Predicted intracellular proteins
- Transporters
Protein Domains for MB Gene
- InterPro:
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for MB Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
P02144- Family:
-
- Belongs to the globin family.
Function for MB Gene
Molecular function for MB Gene
- UniProtKB/Swiss-Prot Function:
- Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles.
- GENATLAS Biochemistry:
- myoglobin,17.5kDa,muscle oxygen-carrying hemoprotein,non covalently
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005344 | oxygen carrier activity | IEA | -- |
| GO:0019825 | oxygen binding | IEA | -- |
| GO:0020037 | heme binding | IEA | -- |
| GO:0046872 | metal ion binding | IEA | -- |
Phenotypes for MB Gene
- MGI mutant phenotypes for MB:
- inferred from 2 alleles
- GenomeRNAi human phenotypes for MB:
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
- Cyagen custom Knockout/knockin (KOKI) mouse models for MB
-
CRISPR Products
-
OriGene CRISPR knockouts for MB
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MB
- genomics-online: gRNA clones - Search results for available MB gene related products
- Applied Biological Materials CRISPR for MB
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MB
- GenScript: Design CRISPR guide RNA sequences for MB
miRNA for MB Gene
- miRTarBase miRNAs that target MB
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MB
- Browse OriGene Inhibitory RNA Products For MB
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MB
- genomics-online: shRNA clones - Search results for available MB gene related products
Clone Products
-
OriGene ORF clones in human for MB
- RC203113
- RC203113L1
- RC203113L2
- RC203113L3
- RC203113L4
- RC212352
- RC212352L1
- RC212352L2
- RC212352L3
- RC212352L4
- RC213272
- RC213272L1
- RC213272L2
- RC213272L3
- RC213272L4
- RC512352
- RG203113
- RG212352
- RG213272
- RC203113L1V
- RC203113L2V
- RC203113L3V
- RC203113L4V
- RC212352L1V
- RC212352L2V
- RC212352L3V
- RC212352L4V
- RC213272L1V
- RC213272L2V
- RC213272L3V
- RC213272L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for MB
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MB
- genomics-online: cdna clones - Search results for available MB gene related products
- orf clones - Search results for available MB gene related products
- Applied Biological Materials Clones for MB
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for MB
No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for MB Gene
Localization for MB Gene
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| cytosol | 5 |
| cytoskeleton | 3 |
| mitochondrion | 3 |
| plasma membrane | 2 |
| nucleus | 2 |
| endoplasmic reticulum | 1 |
| lysosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005829 | cytosol | TAS | -- |
| GO:0070062 | extracellular exosome | HDA | 23533145 |
No data available for Subcellular locations from UniProtKB/Swiss-Prot and Subcellular locations from the Human Protein Atlas (HPA) for MB Gene
Pathways & Interactions for MB Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Glucose / Energy Metabolism | ||
| 2 | Effects of Nitric Oxide | ||
Pathways by source for MB Gene
1 BioSystems pathway for MB Gene
1 Cell Signaling Technology pathway for MB Gene
Interacting Proteins for MB Gene
GPS-Prot Interaction Network for MB
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0001666 | response to hypoxia | IEA | -- |
| GO:0007507 | heart development | IEA | -- |
| GO:0009725 | response to hormone | IEA | -- |
| GO:0015671 | oxygen transport | TAS | -- |
| GO:0031444 | slow-twitch skeletal muscle fiber contraction | IEA | -- |
No data available for SIGNOR curated interactions for MB Gene
Drugs & Compounds for MB Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Oxygen | Approved, Vet_approved | Pharma | 0 | |||
| Carbon monoxide | Approved, Investigational | Pharma | Target, deoxidizer | 132 | ||
| Nitrous acid | Approved, Investigational | Pharma | Target, oxidizer | 0 | ||
| Imidazole | Experimental, Investigational | Pharma | Target | 37 | ||
| 1-Methylimidazole | Experimental | Pharma | Target | 0 |
| Name | Synonyms | Role | CAS Number | PubChem IDs | PubMed IDs |
|---|
Drug Products
Transcripts for MB Gene
mRNA/cDNA for MB Gene
- (5) REFSEQ mRNAs :
- (6) Additional mRNA sequences :
- (801) Selected AceView cDNA sequences:
- (10) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000419229 418 bps (uc062drj.1)
- ENST00000359787 1170 bps (uc003aob.3)
- ENST00000397328 1153 bps (uc003aoa.3)
- ENST00000406324 582 bps (uc062drf.1)
- ENST00000443033 648 bps (uc062drg.1)
Unigene Clusters for MB Gene
- Myoglobin:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for MB
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MB
- genomics-online: gRNA clones - Search results for available MB gene related products
- Applied Biological Materials CRISPR for MB
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for MB
- GenScript: Design CRISPR guide RNA sequences for MB
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MB
- Browse OriGene Inhibitory RNA Products For MB
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MB
- genomics-online: shRNA clones - Search results for available MB gene related products
Clone Products
-
OriGene ORF clones in human for MB
- RC203113
- RC203113L1
- RC203113L2
- RC203113L3
- RC203113L4
- RC212352
- RC212352L1
- RC212352L2
- RC212352L3
- RC212352L4
- RC213272
- RC213272L1
- RC213272L2
- RC213272L3
- RC213272L4
- RC512352
- RG203113
- RG212352
- RG213272
- RC203113L1V
- RC203113L2V
- RC203113L3V
- RC203113L4V
- RC212352L1V
- RC212352L2V
- RC212352L3V
- RC212352L4V
- RC213272L1V
- RC213272L2V
- RC213272L3V
- RC213272L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for MB
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MB
- genomics-online: cdna clones - Search results for available MB gene related products
- orf clones - Search results for available MB gene related products
- Applied Biological Materials Clones for MB
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | ^ | 5a | · | 5b | · | 5c | ^ | 6 | ^ | 7 | ^ | 8a | · | 8b | · | 8c | · | 8d | · | 8e | · | 8f | · | 8g |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | |||||||||||||||||||||||||||||
| SP4: | - | - | - | ||||||||||||||||||||||||||||||||
| SP5: | |||||||||||||||||||||||||||||||||||
| SP6: | - | - | |||||||||||||||||||||||||||||||||
| SP7: | - |
Expression for MB Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
- Adipose (Muscoskeletal System)
- Skeletal Muscle (Muscoskeletal System)
-
Thyroid (Endocrine System)
-
Heart (Cardiovascular System)
mRNA differential expression in normal tissues according to GTEx for MB Gene
This gene is overexpressed in Muscle - Skeletal (x23.8), Heart - Left Ventricle (x17.4), and Heart - Atrial Appendage (x10.9).
This gene is overexpressed in Tonsil (42.8), Heart (11.3), and Oral epithelium (8.9).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MB Gene
NURSA nuclear receptor signaling pathways regulating expression of MB Gene:
MBSOURCE GeneReport for Unigene cluster for MB Gene:
Hs.517586Evidence on tissue expression from TISSUES for MB Gene
- Heart(5)
- Muscle(5)
- Blood(2.8)
- Nervous system(2.7)
- Kidney(2.6)
- Urine(2.6)
- Lung(2.3)
- Liver(2.2)
- Thyroid gland(2)
Primer Products
-
OriGene qPCR primer pairs for MB
-
OriGene qPCR primer pairs and template standards for MB
- genomics-online: primer clones - Search results for available MB gene related products
Gene Expression Assay Products
No data available for mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MB Gene
Orthologs for MB Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | MB 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | MB 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | MB 34 33 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | MB 34 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Mb 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Mb 16 34 33 |
|
||
| chicken (Gallus gallus) |
Aves | MB 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | MB 34 |
|
OneToOne | |
| zebrafish (Danio rerio) |
Actinopterygii | mb 34 33 |
|
OneToOne |
- Species where no ortholog for MB was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- tropical clawed frog (Silurana tropicalis)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for MB Gene
- ENSEMBL:
- Gene Tree for MB (if available)
- TreeFam:
- Gene Tree for MB (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for MB: view image
Paralogs for MB Gene
Variants for MB Gene
| SNP ID | Clin | Chr 22 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000131819 | -- | 35,618,067(-) | C/T | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000485972 | -- | 35,617,823(-) | G/A | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000561591 | -- | 35,622,427(-) | C/T | genic_upstream_transcript_variant, intron_variant | |
| rs1000573299 | -- | 35,611,280(-) | C/A | intron_variant | |
| rs1000633691 | -- | 35,622,123(-) | A/T | genic_upstream_transcript_variant, intron_variant |
Residual Variation Intolerance Score:
36.7% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
0.34;
7.52% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for MB Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MB Gene
Disorders for MB Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| compartment syndrome |
|
|
| medullomyoblastoma |
|
|
| malignant triton tumor |
|
|
| myxosarcoma |
|
|
| malignant mesenchymoma |
|
|
Search MB in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for MB
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for MB Gene
Publications for MB Gene
- The DNA sequence of human chromosome 22. (PMID: 10591208) Dunham I … O'Brien KP (Nature 1999) 2 3 4 58
- Cloning of the human myoglobin gene. (PMID: 2989088) Akaboshi E (Gene 1985) 2 3 4 58
- Expression and functional regulation of myoglobin in epithelial cancers. (PMID: 19541931) Flonta SE … Bardelli A (The American journal of pathology 2009) 3 22 58
- Strong iron demand during hypoxia-induced erythropoiesis is associated with down-regulation of iron-related proteins and myoglobin in human skeletal muscle. (PMID: 17311997) Robach P … Lundby C (Blood 2007) 3 22 58
- A genome annotation-driven approach to cloning the human ORFeome. (PMID: 15461802) Collins JE … Dunham I (Genome biology 2004) 3 4 58
Products for MB Gene
- R&D Systems Antibodies for MB (Myoglobin)
- Browse R&D Systems for Human Recombinant Proteins
- R&D Systems Luminex Assays and other biochemical assays for MB (Myoglobin)
- Browse Human Proteins and Enzymes
- Browse Primary Antibodies
- Browse Proteins and Enzymes
- Browse ELISAs
- Browse Activity Assays
- Browse cDNA Clones
- Browse Cell Culture Products
- Browse Cell Selection and Detection Kits
- Browse DNA Damage and Repair Kits
- Browse ELISpot/FluoroSpot Kits and Development Modules
- Browse Flow Cytometry Kits
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- Browse Peptides
- Browse Proteome Profiler Antibody Arrays
- Browse Small Molecules
- Custom Antibody ServicesOriGene Antibodies for MB
- Custom Assay ServicesOriGene ELISA Kits for MB
- Search Origene for MassSpec and Protein Over-expression Lysates for MB
- Origene Custom Protein Services for MB
- Origene shrna, sirna, and RNAi products in human, mouse, rat for MB
- Browse OriGene Inhibitory RNA Products For MB
- OriGene qPCR primer pairs for MB
- OriGene qPCR primer pairs and template standards for MB
- OriGene CRISPR knockouts for MB
- OriGene ORF clones in human for MB
- RC203113
- RC203113L1
- RC203113L2
- RC203113L3
- RC203113L4
- RC212352
- RC212352L1
- RC212352L2
- RC212352L3
- RC212352L4
- RC213272
- RC213272L1
- RC213272L2
- RC213272L3
- RC213272L4
- RC512352
- RG203113
- RG212352
- RG213272
- RC203113L1V
- RC203113L2V
- RC203113L3V
- RC203113L4V
- RC212352L1V
- RC212352L2V
- RC212352L3V
- RC212352L4V
- RC213272L1V
- RC213272L2V
- RC213272L3V
- RC213272L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For MB
- GenScript: Next-day shipping of latest version cDNA ORF clones for MB in any vector
- GenScript Custom Purified and Recombinant Proteins Services for MB
- GenScript Custom Assay Services for MB
- GenScript Custom overexpressing Cell Line Services for MB
- GenScript: Design CRISPR guide RNA sequences for MB
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for MB
- Sino Biological Human cDNA Clone for MB
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for MB
- Novus Biologicals proteins and lysates for MB
- Novus Biologicals ELISA Kits for MB
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for MB
- Abcam proteins for MB
- Abcam assays for MB
- Find your target
- Browse Primary Antibodies
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- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- antibodies-online: Search results for 433 available MB Antibodies ranked by validation data
- Compare Top MB Antibodies
- Recommended
- 168 WB Antibodies (anti-human)
- 16 IHC (p) Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 11 IHC Antibodies (anti-human)
- 6 RIA Antibodies (anti-human)
- 4 EIA Antibodies (anti-human)
- 4 LF Antibodies (anti-human)
- 2 FACS Antibodies (anti-human)
- 2 IP Antibodies (anti-human)
- 2 TB Antibodies (anti-human)
- 1 IEP Antibody (anti-human)
- 1 IT Antibody (anti-human)
- 29 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 2 IP Antibodies (anti-rat)
- 2 RIA Antibodies (anti-rat)
- 36 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 2 RIA Antibodies (anti-mouse)
- 168 WB Antibodies (anti-human)
- 16 IHC (p) Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 11 IHC Antibodies (anti-human)
- 6 RIA Antibodies (anti-human)
- 4 EIA Antibodies (anti-human)
- 4 LF Antibodies (anti-human)
- 2 FACS Antibodies (anti-human)
- 2 IP Antibodies (anti-human)
- 2 TB Antibodies (anti-human)
- 1 IEP Antibody (anti-human)
- 1 IT Antibody (anti-human)
- 29 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 2 IP Antibodies (anti-rat)
- 2 RIA Antibodies (anti-rat)
- 36 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 2 RIA Antibodies (anti-mouse)
- antibodies-online: Search results for 102 available MB Elisa Kits ranked by validation data
- Compare Top MB Elisa Kits
- Recommended
- 3 Chicken ELISA Kits
- 3 Cow (Bovine) ELISA Kits
- 5 Dog (Canine) ELISA Kits
- 1 Goat ELISA Kit
- 5 Guinea Pig ELISA Kits
- 1 Horse (Equine) ELISA Kit
- 22 Human ELISA Kits
- 5 Monkey ELISA Kits
- 16 Mouse (Murine) ELISA Kits
- 14 Pig (Porcine) ELISA Kits
- 10 Rabbit ELISA Kits
- 14 Rat (Rattus) ELISA Kits
- 2 Sheep (Ovine) ELISA Kits
- 2 Wild boar (Sus scrofa) ELISA Kits
- 3 Chicken ELISA Kits
- 3 Cow (Bovine) ELISA Kits
- 5 Dog (Canine) ELISA Kits
- 1 Goat ELISA Kit
- 5 Guinea Pig ELISA Kits
- 1 Horse (Equine) ELISA Kit
- 22 Human ELISA Kits
- 5 Monkey ELISA Kits
- 16 Mouse (Murine) ELISA Kits
- 14 Pig (Porcine) ELISA Kits
- 10 Rabbit ELISA Kits
- 14 Rat (Rattus) ELISA Kits
- 2 Sheep (Ovine) ELISA Kits
- 2 Wild boar (Sus scrofa) ELISA Kits
- antibodies-online: Search results for 148 available MB Proteins ranked by validation data
- Compare Top MB Proteins
- GeneTex MB Antibody for MB
- Search GeneTex for Proteins for MB
- Santa Cruz Biotechnology (SCBT) Antibodies for MB
- Search Santa Cruz Biotechnology (SCBT) for MB siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for MB
- Horizon Cell Lines for MB
- genomics-online: cdna clones - Search results for available MB gene related products
- orf clones - Search results for available MB gene related products
- genomics-online: gRNA clones - Search results for available MB gene related products
- genomics-online: primer clones - Search results for available MB gene related products
- genomics-online: shRNA clones - Search results for available MB gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for MB
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for MB
- GeneCopoeia miRNA 3'UTR Target clone products for MB
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MB
Sources for MB Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt