Aliases for MAZ Gene
External Ids for MAZ Gene
Previous GeneCards Identifiers for MAZ Gene
GeneCards Summary for MAZ Gene
MAZ (MYC Associated Zinc Finger Protein) is a Protein Coding gene. Diseases associated with MAZ include Amyloidosis and Alzheimer Disease. Among its related pathways are Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. Gene Ontology (GO) annotations related to this gene include nucleic acid binding and chromatin binding. An important paralog of this gene is PATZ1.
UniProtKB/Swiss-Prot Summary for MAZ Gene
May function as a transcription factor with dual roles in transcription initiation and termination. Binds to two sites, ME1a1 and ME1a2, within the MYC promoter having greater affinity for the former. Also binds to multiple G/C-rich sites within the promoter of the Sp1 family of transcription factors. Regulates inflammation-induced expression of serum amyloid A proteins.