External Ids for MATN4 Gene
Previous GeneCards Identifiers for MATN4 Gene
This gene encodes a member of von Willebrand factor A domain-containing protein family. The proteins of this family are thought to be involved in the formation of filamentous networks in the extracellular matrices of various tissues. This family member is thought to be play a role in reorganizing and regenerating the corneal matrix in granular and lattice type I dystrophies. It may also be involved in wound healing in the dentin-pulp complex. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2013]
GeneCards Summary for MATN4 Gene
MATN4 (Matrilin 4) is a Protein Coding gene. Diseases associated with MATN4 include Diabetes Insipidus and Holoprosencephaly 1. Among its related pathways are Degradation of the extracellular matrix and ECM proteoglycans. Gene Ontology (GO) annotations related to this gene include calcium ion binding. An important paralog of this gene is MATN2.
UniProtKB/Swiss-Prot Summary for MATN4 Gene
Major component of the extracellular matrix of cartilage.