The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes. [provided by RefSeq, Jun 2011] See more...

Aliases for MAT2A Gene

Aliases for MAT2A Gene

  • Methionine Adenosyltransferase 2A 2 3 5
  • S-Adenosylmethionine Synthase Isoform Type-2 3 4
  • Methionine Adenosyltransferase II, Alpha 2 3
  • Methionine Adenosyltransferase 2 3 4
  • AdoMet Synthase 2 3 4
  • EC 2.5.1.6 4 52
  • MAT-II 3 4
  • MAT 2 3 4
  • MATA2 3 4
  • Methionine Adenosyltransferase II 4
  • Testicular Tissue Protein Li 121 3
  • AdoMet Synthetase 2 3
  • MATII 3
  • SAMS2 3
  • AMS2 4

External Ids for MAT2A Gene

Previous GeneCards Identifiers for MAT2A Gene

  • GC02P085661
  • GC02P086060
  • GC02P085740
  • GC02P085677
  • GC02P085619
  • GC02P085766
  • GC02P085663

Summaries for MAT2A Gene

Entrez Gene Summary for MAT2A Gene

  • The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes. [provided by RefSeq, Jun 2011]

GeneCards Summary for MAT2A Gene

MAT2A (Methionine Adenosyltransferase 2A) is a Protein Coding gene. Diseases associated with MAT2A include Glycine N-Methyltransferase Deficiency and Familial Thoracic Aortic Aneurysm And Dissection. Among its related pathways are superpathway of methionine degradation and C-MYB transcription factor network. Gene Ontology (GO) annotations related to this gene include methionine adenosyltransferase activity. An important paralog of this gene is MAT1A.

UniProtKB/Swiss-Prot Summary for MAT2A Gene

  • Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.

Additional gene information for MAT2A Gene

No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MAT2A Gene

Genomics for MAT2A Gene

GeneHancer (GH) Regulatory Elements for MAT2A Gene

Promoters and enhancers for MAT2A Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MAT2A on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for MAT2A

Top Transcription factor binding sites by QIAGEN in the MAT2A gene promoter:
  • AREB6
  • Evi-1
  • GR
  • GR-alpha
  • GR-beta
  • PPAR-alpha
  • PPAR-gamma1
  • PPAR-gamma2
  • RelA
  • Sox5

Genomic Locations for MAT2A Gene

Genomic Locations for MAT2A Gene
chr2:85,538,978-85,545,281
(GRCh38/hg38)
Size:
6,304 bases
Orientation:
Plus strand
chr2:85,766,101-85,772,403
(GRCh37/hg19)
Size:
6,303 bases
Orientation:
Plus strand

Genomic View for MAT2A Gene

Genes around MAT2A on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MAT2A Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MAT2A Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MAT2A Gene

Proteins for MAT2A Gene

  • Protein details for MAT2A Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P31153-METK2_HUMAN
    Recommended name:
    S-adenosylmethionine synthase isoform type-2
    Protein Accession:
    P31153
    Secondary Accessions:
    • A8K511
    • B4DN45
    • D6W5L1
    • Q53SP5

    Protein attributes for MAT2A Gene

    Size:
    395 amino acids
    Molecular mass:
    43661 Da
    Cofactor:
    Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
    Cofactor:
    Name=K(+); Xref=ChEBI:CHEBI:29103;
    Quaternary structure:
    • Heterotrimer; composed of a catalytic MAT2A homodimer that binds one regulatory MAT2B chain (PubMed:10644686, PubMed:23189196). Heterohexamer; composed of a central, catalytic MAT2A homotetramer flanked on either side by a regulatory MAT2B chain (PubMed:25075345).
    Miscellaneous:
    • Protein expression is regulated by post-transcriptional regulation: in presence of S-adenosyl-L-methionine, METTL16 binds and methylates the first hairpin of the 3'-UTR region of MAT2A mRNA, impairing MAT2A expression (PubMed:28525753). In S-adenosyl-L-methionine-limiting conditions, METTL16 binds the 3'-UTR region of MAT2A mRNA without methylating it due to the lack of a methyl donor, preventing N6-methylation and promoting expression of MAT2A (PubMed:28525753). Consequences of N6-methylation of MAT2A are however subject to discussion: According to a report, N6-methylation of MAT2A affects MAT2A mRNA splicing (PubMed:28525753). According to a second report, N6-methylation of MAT2A affects MAT2A mRNA stability (By similarity).

    Three dimensional structures from OCA and Proteopedia for MAT2A Gene

    Alternative splice isoforms for MAT2A Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MAT2A Gene

Selected DME Specific Peptides for MAT2A Gene

P31153:
  • GHPDKICD
  • AKVACETV
  • TGRKIIVDTYGG
  • IGAGDQG
  • PLSISIF
  • HGGGAFSGKD
  • FVIGGPQGD
  • AAYGHFGR
  • GRFVIGGP
  • DLDLKKPIY
  • LPWLRPD
  • QVSYAIG
  • GAGDQGLMFGYA
  • HIGYDDS
  • PIRVHTIVISVQHDEEVCLDEMRDALKEK
  • GLTGRKI
  • SYAIGVSHPLS
  • KGFDYKTCNVLVA
  • LFTSESV
  • QSPDIAQG
  • KTQVTVQY
  • VHLDRNEED
  • FTSESVGEGHPDK
  • DQISDAVLD
  • TKVDRSA
  • DYQKVVR
  • PAKYLDE
  • KTCNVLVALEQQSP
  • SDAVLDA
  • NFDLRPGVIV
  • MFGYATDET
  • LCRRVLVQVSY
  • CDQISDA
  • KVDRSAAY

Post-translational modifications for MAT2A Gene

  • Ubiquitination at Lys81, Lys97, Lys61, Lys228, Lys234, Lys350, and Lys367
  • Modification sites at PhosphoSitePlus

Other Protein References for MAT2A Gene

ENSEMBL proteins:
REFSEQ proteins:

Domains & Families for MAT2A Gene

Gene Families for MAT2A Gene

Human Protein Atlas (HPA):
  • Enzymes
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for MAT2A Gene

Suggested Antigen Peptide Sequences for MAT2A Gene

GenScript: Design optimal peptide antigens:
  • S-adenosylmethionine synthase (B4DEX8_HUMAN)
  • S-adenosylmethionine synthase (B4DN45_HUMAN)
  • Methionine adenosyltransferase II (METK2_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P31153

UniProtKB/Swiss-Prot:

METK2_HUMAN :
  • Belongs to the AdoMet synthase family.
Family:
  • Belongs to the AdoMet synthase family.
genes like me logo Genes that share domains with MAT2A: view

Function for MAT2A Gene

Molecular function for MAT2A Gene

UniProtKB/Swiss-Prot Function:
Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L-methionine; Xref=Rhea:RHEA:21080, ChEBI:CHEBI:15377, ChEBI:CHEBI:30616, ChEBI:CHEBI:33019, ChEBI:CHEBI:43474, ChEBI:CHEBI:57844, ChEBI:CHEBI:59789; EC=2.5.1.6; Evidence={ECO:0000269 PubMed:10644686, ECO:0000269 PubMed:23189196, ECO:0000269 PubMed:25075345};.
GENATLAS Biochemistry:
methionine adenosyltransferase,extrahepatic isoform,catalytic specific,subunit alpha,expressed in fetal liver,brain,testis,kidney,lymphocytes,sulfur aminoacid metabolism

Enzyme Numbers (IUBMB) for MAT2A Gene

Phenotypes From GWAS Catalog for MAT2A Gene

Gene Ontology (GO) - Molecular Function for MAT2A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004478 methionine adenosyltransferase activity IDA,IBA 7665609
GO:0005515 protein binding IPI 10644686
GO:0005524 ATP binding IEA --
GO:0016740 transferase activity IEA --
GO:0042802 identical protein binding IPI 25416956
genes like me logo Genes that share ontologies with MAT2A: view
genes like me logo Genes that share phenotypes with MAT2A: view

Human Phenotype Ontology for MAT2A Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for MAT2A Gene

MGI Knock Outs for MAT2A:
  • Mat2a Mat2a<tm1a(EUCOMM)Hmgu>
  • Mat2a Mat2a<tm1b(EUCOMM)Hmgu>

Animal Model Products

  • Taconic Biosciences Mouse Models for MAT2A

CRISPR Products

miRNA for MAT2A Gene

miRTarBase miRNAs that target MAT2A

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MAT2A

No data available for Transcription Factor Targets and HOMER Transcription for MAT2A Gene

Localization for MAT2A Gene

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MAT2A gene
Compartment Confidence
cytosol 4
nucleus 3
mitochondrion 2
plasma membrane 1
extracellular 1
cytoskeleton 1
peroxisome 1
endoplasmic reticulum 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (2)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for MAT2A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005829 cytosol TAS --
GO:0048269 methionine adenosyltransferase complex IBA,IDA 10644686
genes like me logo Genes that share ontologies with MAT2A: view

No data available for Subcellular locations from UniProtKB/Swiss-Prot for MAT2A Gene

Pathways & Interactions for MAT2A Gene

genes like me logo Genes that share pathways with MAT2A: view

Pathways by source for MAT2A Gene

1 GeneGo (Thomson Reuters) pathway for MAT2A Gene
  • Methionine metabolism

UniProtKB/Swiss-Prot P31153-METK2_HUMAN

  • Pathway: Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.

Gene Ontology (GO) - Biological Process for MAT2A Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006556 S-adenosylmethionine biosynthetic process IEA --
GO:0006730 one-carbon metabolic process IEA --
GO:0032259 methylation TAS --
GO:0034214 protein hexamerization IDA 25075345
GO:0051291 protein heterooligomerization IDA 25075345
genes like me logo Genes that share ontologies with MAT2A: view

No data available for SIGNOR curated interactions for MAT2A Gene

Drugs & Compounds for MAT2A Gene

(9) Drugs for MAT2A Gene - From: DrugBank, HMDB, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Methionine Approved Nutra Enzyme, substrate 114
Ademetionine Approved, Investigational Nutra Target, cofactor 0
Cobalt Approved, Experimental Pharma 198
Magnesium Approved, Experimental, Investigational Pharma 0
Phosphoric acid Approved Pharma 0

(4) Additional Compounds for MAT2A Gene - From: Novoseek and HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
s-adenosylmethionine
  • (3S)-5'-[(3-amino-3-Carboxypropyl)methylsulfonio]-5'-deoxyadenosine, inner salt
  • [1-(Adenin-9-yl)-1,5-dideoxy-beta-D-ribofuranos-5-yl][(3S)-3-amino-3-carboxypropyl](methyl)sulfonium
  • Acylcarnitine
  • AdoMet
  • S-(5'-Deoxyadenosin-5'-yl)-L-methionine
485-80-3
pyrophosphate
  • [(ho)2P(O)OP(O)(OH)2]
  • Acide diphosphorique
  • Diphosphorsaeure
  • H4P2O7
  • PYROphosphATE
14000-31-8
Se-Adenosylselenomethionine
genes like me logo Genes that share compounds with MAT2A: view

Transcripts for MAT2A Gene

mRNA/cDNA for MAT2A Gene

1 REFSEQ mRNAs :
17 NCBI additional mRNA sequence :
6 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MAT2A

Alternative Splicing Database (ASD) splice patterns (SP) for MAT2A Gene

ExUns: 1a · 1b ^ 2a · 2b ^ 3a · 3b ^ 4 ^ 5a · 5b ^ 6a · 6b · 6c ^ 7a · 7b ^ 8 ^ 9a · 9b ^ 10
SP1: - - - - -
SP2: - - -
SP3: - -
SP4: - - -
SP5: -
SP6:
SP7:
SP8: -

Relevant External Links for MAT2A Gene

GeneLoc Exon Structure for
MAT2A

Expression for MAT2A Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MAT2A Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MAT2A Gene



Protein tissue co-expression partners for MAT2A Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MAT2A

SOURCE GeneReport for Unigene cluster for MAT2A Gene:

Hs.516157

mRNA Expression by UniProt/SwissProt for MAT2A Gene:

P31153-METK2_HUMAN
Tissue specificity: Detected in kidney.

Evidence on tissue expression from TISSUES for MAT2A Gene

  • Nervous system(5)
  • Kidney(4.8)
  • Lung(4.8)
  • Muscle(4.4)
  • Liver(3.8)
  • Skin(3.3)
  • Blood(3)
  • Stomach(3)
  • Intestine(2.9)
  • Eye(2.8)
  • Pancreas(2.5)
  • Thyroid gland(2.5)
  • Adrenal gland(2.3)
  • Gall bladder(2.2)
  • Heart(2)
genes like me logo Genes that share expression patterns with MAT2A: view

No data available for mRNA differential expression in normal tissues , Protein differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for MAT2A Gene

Orthologs for MAT2A Gene

This gene was present in the common ancestor of eukaryotes.

Orthologs for MAT2A Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia MAT2A 31 30
  • 99.49 (n)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia MAT2A 31
  • 98 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia MAT2A 31
  • 98 (a)
OneToOne
dog
(Canis familiaris)
Mammalia MAT2A 31 30
  • 95.02 (n)
OneToOne
cow
(Bos Taurus)
Mammalia MAT2A 31 30
  • 94.6 (n)
OneToOne
rat
(Rattus norvegicus)
Mammalia Mat2a 30
  • 93.5 (n)
mouse
(Mus musculus)
Mammalia Mat2a 17 31 30
  • 93.16 (n)
chicken
(Gallus gallus)
Aves -- 31
  • 72 (a)
ManyToMany
lizard
(Anolis carolinensis)
Reptilia MAT2A 31
  • 91 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia mat2a 30
  • 79.92 (n)
MGC76253 30
African clawed frog
(Xenopus laevis)
Amphibia m(2)21ab-prov 30
zebrafish
(Danio rerio)
Actinopterygii mat2aa 31
  • 92 (a)
OneToMany
mat2ab 31 30
  • 75.51 (n)
OneToMany
fruit fly
(Drosophila melanogaster)
Insecta M(2)21AB 32
  • 74 (a)
Sam-S 31 30
  • 67.71 (n)
OneToMany
African malaria mosquito
(Anopheles gambiae)
Insecta AgaP_AGAP009447 30
  • 65.56 (n)
worm
(Caenorhabditis elegans)
Secernentea C06E7.1a 32
  • 74 (a)
sams-4 31
  • 68 (a)
ManyToMany
sams-5 31
  • 67 (a)
ManyToMany
C49F5.1 32
  • 67 (a)
sams-3 31 30
  • 66.67 (n)
ManyToMany
sams-1 31
  • 63 (a)
ManyToMany
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SAM2 31
  • 66 (a)
ManyToMany
SAM1 31 30
  • 63.51 (n)
ManyToMany
K. lactis yeast
(Kluyveromyces lactis)
Saccharomycetes KLLA0C01782g 30
  • 64.46 (n)
A. gosspyii yeast
(Ashbya gossypii)
Saccharomycetes AGOS_AFR692C 30
  • 60.67 (n)
thale cress
(Arabidopsis thaliana)
eudicotyledons MAT3 30
  • 63.23 (n)
fission yeast
(Schizosaccharomyces pombe)
Schizosaccharomycetes sam1 30
  • 65.26 (n)
bread mold
(Neurospora crassa)
Ascomycetes NCU02657 30
  • 64.79 (n)
sea squirt
(Ciona savignyi)
Ascidiacea CSA.10263 31
  • 63 (a)
OneToMany
Species where no ortholog for MAT2A was found in the sources mined by GeneCards:
  • Actinobacteria (Mycobacterium tuberculosis)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for MAT2A Gene

ENSEMBL:
Gene Tree for MAT2A (if available)
TreeFam:
Gene Tree for MAT2A (if available)
Aminode:
Evolutionary constrained regions (ECRs) for MAT2A: view image

Paralogs for MAT2A Gene

Paralogs for MAT2A Gene

(1) SIMAP similar genes for MAT2A Gene using alignment to 3 proteins:

  • METK2_HUMAN
  • B4DEX8_HUMAN
  • B4DN45_HUMAN

Pseudogenes.org Pseudogenes for MAT2A Gene

genes like me logo Genes that share paralogs with MAT2A: view

Variants for MAT2A Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MAT2A Gene

SNP ID Clinical significance and condition Chr 02 pos Variation AA Info Type
658008 Uncertain Significance: Thoracic aortic aneurysm and aortic dissection 85,539,319(+) C/T MISSENSE_VARIANT
661889 Uncertain Significance: Thoracic aortic aneurysm and aortic dissection 85,542,998(+) A/T MISSENSE_VARIANT
668230 Likely Benign: not provided 85,542,763(+) A/G INTRON_VARIANT
672424 Likely Benign: not provided 85,542,304(+) G/A SYNONYMOUS_VARIANT
674698 Benign: not provided 85,542,123(+) G/A INTRON_VARIANT

Additional dbSNP identifiers (rs#s) for MAT2A Gene

Structural Variations from Database of Genomic Variants (DGV) for MAT2A Gene

Variant ID Type Subtype PubMed ID
nsv2811 CNV insertion 18451855
nsv961801 CNV duplication 23825009

Variation tolerance for MAT2A Gene

Residual Variation Intolerance Score: 22.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.17; 3.89% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for MAT2A Gene

Human Gene Mutation Database (HGMD)
MAT2A
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MAT2A

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MAT2A Gene

Disorders for MAT2A Gene

MalaCards: The human disease database

(8) MalaCards diseases for MAT2A Gene - From: Orphanet, DISEASES, and GeneCards

Disorder Aliases PubMed IDs
glycine n-methyltransferase deficiency
  • gnmt deficiency
familial thoracic aortic aneurysm and dissection
  • annuloaortic ectasia
acute maxillary sinusitis
  • acute antritis
aortic disease
  • aortic disorder
hypermethioninemia
  • mat deficiency
- elite association - COSMIC cancer census association via MalaCards
Search MAT2A in MalaCards View complete list of genes associated with diseases

Additional Disease Information for MAT2A

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with MAT2A: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MAT2A Gene

Publications for MAT2A Gene

  1. Role of methionine adenosyltransferase 2A and S-adenosylmethionine in mitogen-induced growth of human colon cancer cells. (PMID: 17631143) Chen H … Lu SC (Gastroenterology 2007) 3 23 26 54
  2. Cloning, expression, and functional characterization of the beta regulatory subunit of human methionine adenosyltransferase (MAT II). (PMID: 10644686) LeGros HL … Kotb M (The Journal of biological chemistry 2000) 3 4 23 54
  3. Cloning and functional characterization of the 5'-flanking region of human methionine adenosyltransferase 2A gene. (PMID: 9703951) Mao Z … Lu SC (Biochemical and biophysical research communications 1998) 2 3 23 54
  4. Molecular cloning and developmental expression of a human kidney S-adenosylmethionine synthetase. (PMID: 1426236) Horikawa S … Tsukada K (FEBS letters 1992) 2 3 4 54
  5. The U6 snRNA m6A Methyltransferase METTL16 Regulates SAM Synthetase Intron Retention. (PMID: 28525753) Pendleton KE … Conrad NK (Cell 2017) 3 4 54

Products for MAT2A Gene

Sources for MAT2A Gene