Aliases for MAT2A Gene
External Ids for MAT2A Gene
Previous GeneCards Identifiers for MAT2A Gene
The protein encoded by this gene catalyzes the production of S-adenosylmethionine (AdoMet) from methionine and ATP. AdoMet is the key methyl donor in cellular processes. [provided by RefSeq, Jun 2011]
GeneCards Summary for MAT2A Gene
MAT2A (Methionine Adenosyltransferase 2A) is a Protein Coding gene. Diseases associated with MAT2A include Glycine N-Methyltransferase Deficiency and Familial Thoracic Aortic Aneurysm And Dissection. Among its related pathways are superpathway of methionine degradation and C-MYB transcription factor network. Gene Ontology (GO) annotations related to this gene include methionine adenosyltransferase activity. An important paralog of this gene is MAT1A.
UniProtKB/Swiss-Prot Summary for MAT2A Gene
Catalyzes the formation of S-adenosylmethionine from methionine and ATP. The reaction comprises two steps that are both catalyzed by the same enzyme: formation of S-adenosylmethionine (AdoMet) and triphosphate, and subsequent hydrolysis of the triphosphate.