Aliases for MAST2 Gene
External Ids for MAST2 Gene
Previous GeneCards Identifiers for MAST2 Gene
GeneCards Summary for MAST2 Gene
MAST2 (Microtubule Associated Serine/Threonine Kinase 2) is a Protein Coding gene. Diseases associated with MAST2 include Breast Mucinous Carcinoma and Mega-Corpus-Callosum Syndrome With Cerebellar Hypoplasia And Cortical Malformations. Gene Ontology (GO) annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is MAST4.
UniProtKB/Swiss-Prot Summary for MAST2 Gene
Appears to link the dystrophin/utrophin network with microtubule filaments via the syntrophins. Phosphorylation of DMD or UTRN may modulate their affinities for associated proteins. Functions in a multi-protein complex in spermatid maturation. Regulates lipopolysaccharide-induced IL-12 synthesis in macrophages by forming a complex with TRAF6, resulting in the inhibition of TRAF6 NF-kappa-B activation (By similarity).