This locus represents a small RNA that is related to tRNA and is localized to the cytoplasm. This RNA is not thought to be transcribed independently; it is instead cleaved by RNase P and RNase Z from the MALAT1 (metastasis associated lung adenocarcinoma transcript 1) long non-coding RNA precursor transcript. [provided by RefSeq, Nov 2016] See more...

Aliases for MASCRNA Gene

Data sources for MASCRNA Gene:

Subcategory (RNA class) for MASCRNA Gene

sRNA

Aliases for MASCRNA Gene

External Ids for MASCRNA Gene

Previous GeneCards Identifiers for MASCRNA Gene

  • GC11U902916
  • GC11P065876

Summaries for MASCRNA Gene

Entrez Gene Summary for MASCRNA Gene

  • This locus represents a small RNA that is related to tRNA and is localized to the cytoplasm. This RNA is not thought to be transcribed independently; it is instead cleaved by RNase P and RNase Z from the MALAT1 (metastasis associated lung adenocarcinoma transcript 1) long non-coding RNA precursor transcript. [provided by RefSeq, Nov 2016]

GeneCards Summary for MASCRNA Gene

MASCRNA (MALAT1-Associated Small Cytoplasmic RNA) is an RNA Gene, and is affiliated with the sRNA class.

Rfam classification for MASCRNA Gene

  • MALAT1-associated small cytoplasmic RNA/MEN beta RNA

Additional gene information for MASCRNA Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary and piRNA Summary for MASCRNA Gene

Genomics for MASCRNA Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MASCRNA Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH11J065470 Promoter/Enhancer 3.2 VISTA EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 0.4 -16.0 -15972 40.1 CHD2 TBP ZBTB10 SP1 BCL11A MXD4 FEZF1 CEBPA NR2C1 MNT MALAT1 HSALNG0084901 LINC02736 SF1 POLA2 ZFPL1 PCNX3 MUS81 EIF1AD SART1
GH11J065510 Promoter/Enhancer 1.4 Ensembl ENCODE dbSUPER 0.7 +4.9 4868 1.1 MNT IKZF1 CTCF ZEB1 THAP11 CEBPB ARNT SIN3A REST VEZF1 TALAM1 piR-50437-081 ENSG00000255478 SLC25A45 FRMD8 MIR612 CDC42EP2 EHBP1L1 KCNK7 SNX32
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MASCRNA on the GeneHancer Hub at the UCSC Golden Path

Genomic Locations for MASCRNA Gene

Latest Assembly
chr11:65,506,117-65,506,174
(GRCh38/hg38)
Size:
58 bases
Orientation:
Plus strand

Previous Assembly
chr11:65,273,588-65,273,645
(GRCh37/hg19 by Entrez Gene)
Size:
58 bases
Orientation:
Plus strand

Genomic View for MASCRNA Gene

Genes around MASCRNA on UCSC Golden Path with GeneCards custom track
MASCRNA in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Cytogenetic band:
MASCRNA Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MASCRNA Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MASCRNA Gene

Proteins for MASCRNA Gene

Post-translational modifications for MASCRNA Gene

No Post-translational modifications

No data available for DME Specific Peptides for MASCRNA Gene

Domains & Families for MASCRNA Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MASCRNA Gene

Function for MASCRNA Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MASCRNA Gene

Localization for MASCRNA Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MASCRNA Gene

Pathways & Interactions for MASCRNA Gene

PathCards logo

SuperPathways for MASCRNA Gene

No Data Available

Gene Ontology (GO) - Biological Process for MASCRNA Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for MASCRNA Gene

Drugs & Compounds for MASCRNA Gene

No Compound Related Data Available

Transcripts for MASCRNA Gene

Non-coding RNA (ncRNA) Transcripts from RNAcentral for MASCRNA Gene

RNAcentral Transcript ID Subcategory Length (nts) # of Sources Source Identifiers and Annotations
URS000064EB37_9606 sRNA 57 2

Ensembl: ENST00000611300 (view in UCSC) ,

Rfam: RF01684,

URS0000812213_9606 scRNA 58 1

RefSeq: NR_144569,

URS00004B92A1_9606 scRNA 58 1

ENA: FJ209302.1:1..61:ncRNA,

URS0001BC6B17_9606 sRNA 57 1

Rfam: RF01684,

URS0001BC7820_9606 sRNA 57 1

Rfam: RF01684,

MASCRNA in the GeneCaRNA (GeneCards ncRNA compendium) hub on the UCSC Golden Path

Additional transcripts not in RNAcentral for MASCRNA Gene

1 NCBI additional mRNA sequence :

Alternative Splicing Database (ASD) splice patterns (SP) for MASCRNA Gene

No ASD Table

Relevant External Links for MASCRNA Gene

GeneLoc Exon Structure for
MASCRNA

Expression for MASCRNA Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MASCRNA Gene

Orthologs for MASCRNA Gene

Evolution for MASCRNA Gene

ENSEMBL:
Gene Tree for MASCRNA (if available)
TreeFam:
Gene Tree for MASCRNA (if available)

No data available for Orthologs for MASCRNA Gene

Paralogs for MASCRNA Gene

No data available for Paralogs for MASCRNA Gene

Variants for MASCRNA Gene

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MASCRNA Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for MASCRNA Gene

Disorders for MASCRNA Gene

No disorders were found for MASCRNA Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for MASCRNA Gene

Publications for MASCRNA Gene

  1. Natural antisense RNA promotes 3' end processing and maturation of MALAT1 lncRNA. (PMID: 26826711) Zong X … Prasanth KV (Nucleic acids research 2016) 3
  2. Long noncoding RNA MALAT1-derived mascRNA is involved in cardiovascular innate immunity. (PMID: 26823496) Gast M … Poller W (Journal of molecular cell biology 2016) 3
  3. 3' end processing of a long nuclear-retained noncoding RNA yields a tRNA-like cytoplasmic RNA. (PMID: 19041754) Wilusz JE … Spector DL (Cell 2008) 3

No data available for Mastermind for MASCRNA Gene

Products for MASCRNA Gene

Sources for MASCRNA Gene