Aliases for MARS2 Gene
External Ids for MARS2 Gene
Previous GeneCards Identifiers for MARS2 Gene
This gene produces a mitochondrial methionyl-tRNA synthetase protein that is encoded by the nuclear genome and imported to the mitochondrion. This protein likely functions as a monomer and is predicted to localize to the mitochondrial matrix. Mutations in this gene are associated with the autosomal recessive neurodegenerative disease spastic ataxia-3 (SPAX3). [provided by RefSeq, Apr 2014]
GeneCards Summary for MARS2 Gene
MARS2 (Methionyl-TRNA Synthetase 2, Mitochondrial) is a Protein Coding gene. Diseases associated with MARS2 include Combined Oxidative Phosphorylation Deficiency 25 and Spastic Ataxia 3, Autosomal Recessive. Among its related pathways are Gene Expression and tRNA Aminoacylation. Gene Ontology (GO) annotations related to this gene include nucleotide binding and methionine-tRNA ligase activity.