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Aliases for MARCH1 Gene

Aliases for MARCH1 Gene

  • Membrane Associated Ring-CH-Type Finger 1 2 3 5
  • Membrane-Associated Ring Finger (C3HC4) 1, E3 Ubiquitin Protein Ligase 2 3
  • Membrane-Associated RING Finger Protein 1 3 4
  • RING-Type E3 Ubiquitin Transferase MARCH1 3 4
  • Membrane-Associated RING-CH Protein I 3 4
  • RING Finger Protein 171 3 4
  • MARCH-I 3 4
  • RNF171 3 4
  • Membrane-Associated Ring Finger (C3HC4) 1 2
  • E3 Ubiquitin-Protein Ligase MARCH1 3
  • Membrane Associated Ring Finger 1 3
  • EC 4

External Ids for MARCH1 Gene

Previous GeneCards Identifiers for MARCH1 Gene

  • GC04M164806
  • GC04M164668
  • GC04M164448
  • GC04M160199

Summaries for MARCH1 Gene

Entrez Gene Summary for MARCH1 Gene

  • MARCH1 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH1 downregulates the surface expression of major histocompatibility complex (MHC) class II molecules (see MIM 142880) and other glycoproteins by directing them to the late endosomal/lysosomal compartment (Bartee et al., 2004 [PubMed 14722266]; Thibodeau et al., 2008 [PubMed 18389477]; De Gassart et al., 2008 [PubMed 18305173]).[supplied by OMIM, Mar 2010]

GeneCards Summary for MARCH1 Gene

MARCH1 (Membrane Associated Ring-CH-Type Finger 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include ligase activity and MHC protein binding. An important paralog of this gene is MARCH8.

UniProtKB/Swiss-Prot for MARCH1 Gene

  • E3 ubiquitin-protein ligase that mediates ubiquitination of TFRC, CD86, FAS and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. By constitutively ubiquitinating MHC class II proteins in immature dendritic cells, down-regulates their cell surface localization thus sequestering them in the intracellular endosomal system.

Additional gene information for MARCH1 Gene

No data available for CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MARCH1 Gene

Genomics for MARCH1 Gene

GeneHancer (GH) Regulatory Elements for MARCH1 Gene

Promoters and enhancers for MARCH1 Gene
GeneHancer (GH) Identifier GH Type GH
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH04J163610 Promoter/Enhancer 2 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 667 +771.6 771584 3.4 POLR2A JUNB BATF ATF2 IRF4 MARCH1 ENSG00000273449 PIR37872
GH04J164383 Promoter/Enhancer 1.1 EPDnew ENCODE 650.7 +0.3 283 1.3 CTCF MXI1 SUZ12 SIN3A ZNF398 ATF2 ZIC2 ZNF335 ZNF692 POLR2A MARCH1 GC04M163839 ANP32C
GH04J164197 Promoter 0.5 EPDnew 650.1 +186.5 186542 0.1 ANP32C MARCH1 LOC100288073 GC04M163839
GH04J163493 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE 47.3 +889.3 889310 3.4 MLX ZFP64 DMAP1 IRF4 YY1 ZNF213 E2F8 ZNF143 NFYC ZC3H11A TMA16 MARCH1 ENSG00000273449 TKTL2
GH04J163544 Enhancer 1.1 Ensembl ENCODE dbSUPER 48.8 +839.1 839130 1.4 CTCF BACH1 MZF1 RAD21 CC2D1A FOXK2 POLR2A SMC3 ZNF143 ZNF444 MARCH1 TMA16 TKTL2 ENSG00000273449 PIR37872
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MARCH1 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the MARCH1 gene promoter:
  • LCR-F1
  • Pax-4a
  • Nkx6-1
  • GR-beta
  • GR-alpha
  • GR
  • En-1
  • HTF
  • FOXJ2 (long isoform)
  • FOXJ2

Genomic Locations for MARCH1 Gene

Genomic Locations for MARCH1 Gene
859,753 bases
Minus strand
859,753 bases
Minus strand

Genomic View for MARCH1 Gene

Genes around MARCH1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MARCH1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MARCH1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MARCH1 Gene

Proteins for MARCH1 Gene

  • Protein details for MARCH1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Recommended name:
    E3 ubiquitin-protein ligase MARCH1
    Protein Accession:
    Secondary Accessions:
    • D3DP29
    • Q9NWR0

    Protein attributes for MARCH1 Gene

    289 amino acids
    Molecular mass:
    32308 Da
    Quaternary structure:
    No Data Available

    Alternative splice isoforms for MARCH1 Gene


neXtProt entry for MARCH1 Gene

Post-translational modifications for MARCH1 Gene

  • Has a short half-life. Instability/short half-life permits rapid changes that allow efficient induction of antigen presentation once antigen presenting cells, APCs, receive maturation signals. Small changes in protein levels significantly alter the cell surface display of MHC class II proteins (By similarity).
  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for MARCH1 Gene

Domains & Families for MARCH1 Gene

Gene Families for MARCH1 Gene

Human Protein Atlas (HPA):
  • Enzymes
  • Predicted intracellular proteins
  • Predicted membrane proteins

Protein Domains for MARCH1 Gene

Graphical View of Domain Structure for InterPro Entry



  • The RING-CH-type zinc finger domain is required for E3 ligase activity.
  • The RING-CH-type zinc finger domain is required for E3 ligase activity.
genes like me logo Genes that share domains with MARCH1: view

No data available for Suggested Antigen Peptide Sequences for MARCH1 Gene

Function for MARCH1 Gene

Molecular function for MARCH1 Gene

UniProtKB/Swiss-Prot Function:
E3 ubiquitin-protein ligase that mediates ubiquitination of TFRC, CD86, FAS and MHC class II proteins, such as HLA-DR alpha and beta, and promotes their subsequent endocytosis and sorting to lysosomes via multivesicular bodies. By constitutively ubiquitinating MHC class II proteins in immature dendritic cells, down-regulates their cell surface localization thus sequestering them in the intracellular endosomal system.
UniProtKB/Swiss-Prot CatalyticActivity:
S-ubiquitinyl-[E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + N(6)-ubiquitinyl-[acceptor protein]-L-lysine.
UniProtKB/Swiss-Prot Induction:
By IL10/interleukin-10.

Enzyme Numbers (IUBMB) for MARCH1 Gene

Phenotypes From GWAS Catalog for MARCH1 Gene

Gene Ontology (GO) - Molecular Function for MARCH1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004842 ubiquitin-protein transferase activity IDA 14722266
GO:0008270 zinc ion binding IEA --
GO:0016740 transferase activity IEA --
GO:0042287 MHC protein binding IDA 18389477
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with MARCH1: view
genes like me logo Genes that share phenotypes with MARCH1: view

Animal Models for MARCH1 Gene

MGI Knock Outs for MARCH1:

Clone Products

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for MARCH1 Gene

Localization for MARCH1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MARCH1 Gene

Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Cytoplasmic vesicle membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Early endosome membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein.

Subcellular locations from

Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MARCH1 gene
Compartment Confidence
plasma membrane 5
lysosome 5
endosome 5
endoplasmic reticulum 4
golgi apparatus 4
mitochondrion 2
cytosol 2
extracellular 1

Subcellular locations from the

Human Protein Atlas (HPA)

Gene Ontology (GO) - Cellular Components for MARCH1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005764 lysosome IDA,IEA 14722266
GO:0005765 lysosomal membrane ISS --
GO:0005768 endosome IEA,IDA 14722266
GO:0005789 endoplasmic reticulum membrane ISS --
GO:0005794 Golgi apparatus IEA --
genes like me logo Genes that share ontologies with MARCH1: view

Pathways & Interactions for MARCH1 Gene

SuperPathways for MARCH1 Gene

No Data Available

UniProtKB/Swiss-Prot Q8TCQ1-MARH1_HUMAN

  • Pathway: Protein modification; protein ubiquitination.

Gene Ontology (GO) - Biological Process for MARCH1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000209 protein polyubiquitination IDA 19117940
GO:0002376 immune system process IEA --
GO:0002495 antigen processing and presentation of peptide antigen via MHC class II IDA 18389477
GO:0006955 immune response IDA 18305173
GO:0016567 protein ubiquitination IEA --
genes like me logo Genes that share ontologies with MARCH1: view

No data available for Pathways by source and SIGNOR curated interactions for MARCH1 Gene

Drugs & Compounds for MARCH1 Gene

(3) Drugs for MARCH1 Gene - From: HMDB

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Phosphoric acid Approved Pharma 0
Adenosine monophosphate Approved, Investigational Nutra 0
ATP Investigational Nutra Agonist, Activator, Full agonist, Antagonist, Potentiation, Pore Blocker 0

(1) Additional Compounds for MARCH1 Gene - From: HMDB

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
  • [(ho)2P(O)OP(O)(OH)2]
  • Acide diphosphorique
  • Diphosphorsaeure
  • H4P2O7
  • PYROphosphATE
genes like me logo Genes that share compounds with MARCH1: view

Transcripts for MARCH1 Gene

Unigene Clusters for MARCH1 Gene

Membrane-associated ring finger (C3HC4) 1, E3 ubiquitin protein ligase:
Representative Sequences:

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for MARCH1 Gene

No ASD Table

Relevant External Links for MARCH1 Gene

GeneLoc Exon Structure for
ECgene alternative splicing isoforms for

Expression for MARCH1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MARCH1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for MARCH1 Gene

This gene is overexpressed in Retina (69.0).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for MARCH1 Gene

Protein tissue co-expression partners for MARCH1 Gene

SOURCE GeneReport for Unigene cluster for MARCH1 Gene:


mRNA Expression by UniProt/SwissProt for MARCH1 Gene:

Tissue specificity: Expressed in antigen presenting cells, APCs, located in lymph nodes and spleen. Also expressed in lung. Expression is high in follicular B-cells, moderate in dendritic cells and low in splenic T-cells.

Evidence on tissue expression from TISSUES for MARCH1 Gene

  • Nervous system(4.6)
  • Intestine(4.2)
  • Lymph node(2.7)
  • Spleen(2.7)
genes like me logo Genes that share expression patterns with MARCH1: view

No data available for mRNA differential expression in normal tissues and Phenotype-based relationships between genes and organs from Gene ORGANizer for MARCH1 Gene

Orthologs for MARCH1 Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for MARCH1 Gene

Organism Taxonomy Gene Similarity Type Details
(Pan troglodytes)
Mammalia MARCH1 34 33
  • 99.08 (n)
(Ornithorhynchus anatinus)
Mammalia MARCH1 34
  • 93 (a)
(Canis familiaris)
Mammalia MARCH1 34 33
  • 91.46 (n)
(Mus musculus)
Mammalia March1 16 34 33
  • 91.35 (n)
(Bos Taurus)
Mammalia MARCH1 34 33
  • 81.38 (n)
(Monodelphis domestica)
Mammalia MARCH1 34
  • 44 (a)
(Gallus gallus)
Aves MARCH1 34
  • 89 (a)
(Anolis carolinensis)
Reptilia MARCH1 34
  • 87 (a)
(Danio rerio)
Actinopterygii march1 34
  • 36 (a)
fruit fly
(Drosophila melanogaster)
Insecta CG4080 34
  • 16 (a)
baker's yeast
(Saccharomyces cerevisiae)
Saccharomycetes SSM4 34
  • 3 (a)
sea squirt
(Ciona savignyi)
Ascidiacea -- 34
  • 55 (a)
Species where no ortholog for MARCH1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • tropical clawed frog (Silurana tropicalis)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for MARCH1 Gene

Gene Tree for MARCH1 (if available)
Gene Tree for MARCH1 (if available)
Evolutionary constrained regions (ECRs) for MARCH1: view image

Paralogs for MARCH1 Gene

Paralogs for MARCH1 Gene

(4) SIMAP similar genes for MARCH1 Gene using alignment to 4 proteins:

  • B7Z739_HUMAN
genes like me logo Genes that share paralogs with MARCH1: view

Variants for MARCH1 Gene

Sequence variations from dbSNP and Humsavar for MARCH1 Gene

SNP ID Clin Chr 04 pos Variation AA Info Type
rs1000010873 -- 164,361,804(-) T/C genic_upstream_transcript_variant, intron_variant
rs1000011408 -- 164,316,677(-) G/A genic_upstream_transcript_variant, intron_variant
rs1000011628 -- 163,956,607(-) G/A genic_upstream_transcript_variant, intron_variant
rs1000014017 -- 164,275,599(-) T/A genic_upstream_transcript_variant, intron_variant
rs1000019147 -- 163,724,277(-) C/T genic_upstream_transcript_variant, intron_variant

Structural Variations from Database of Genomic Variants (DGV) for MARCH1 Gene

Variant ID Type Subtype PubMed ID
dgv1539e212 CNV loss 25503493
dgv1540e212 CNV loss 25503493
dgv1541e212 CNV loss 25503493
dgv1542e212 CNV loss 25503493
dgv2931n106 CNV deletion 24896259
dgv5458n100 CNV gain 25217958
dgv5459n100 CNV loss 25217958
dgv5460n100 CNV gain 25217958
dgv9367n54 CNV loss 21841781
dgv9368n54 CNV loss 21841781
esv1002929 CNV deletion 20482838
esv1471717 CNV insertion 17803354
esv1594178 CNV deletion 17803354
esv1773945 CNV deletion 17803354
esv2184592 CNV deletion 18987734
esv2224163 CNV deletion 18987734
esv22863 CNV loss 19812545
esv2293577 CNV deletion 18987734
esv2453665 CNV deletion 19546169
esv26379 CNV loss 19812545
esv2663902 CNV deletion 23128226
esv2665160 CNV deletion 23128226
esv2665814 CNV deletion 23128226
esv2671056 CNV deletion 23128226
esv2671614 CNV deletion 23128226
esv2672728 CNV deletion 23128226
esv2674636 CNV deletion 23128226
esv2676542 CNV deletion 23128226
esv2677589 CNV deletion 23128226
esv2728666 CNV deletion 23290073
esv2728667 CNV deletion 23290073
esv2728668 CNV deletion 23290073
esv2728669 CNV deletion 23290073
esv2728670 CNV deletion 23290073
esv2728671 CNV deletion 23290073
esv2728672 CNV deletion 23290073
esv2728674 CNV deletion 23290073
esv2728675 CNV deletion 23290073
esv2728676 CNV deletion 23290073
esv2728677 CNV deletion 23290073
esv2728678 CNV deletion 23290073
esv2728679 CNV deletion 23290073
esv2760839 CNV loss 21179565
esv2762472 CNV loss 21179565
esv29373 CNV loss 19812545
esv29511 CNV gain 19812545
esv3297829 CNV deletion 24192839
esv3303597 CNV mobile element insertion 20981092
esv3304345 CNV mobile element insertion 20981092
esv3308638 CNV mobile element insertion 20981092
esv3309308 CNV mobile element insertion 20981092
esv3329057 CNV insertion 20981092
esv3339212 CNV insertion 20981092
esv3371675 CNV insertion 20981092
esv3375283 CNV insertion 20981092
esv3564916 CNV deletion 23714750
esv3564917 CNV deletion 23714750
esv3564918 CNV deletion 23714750
esv3564919 CNV deletion 23714750
esv3564928 CNV deletion 23714750
esv3564929 CNV deletion 23714750
esv3569797 CNV loss 25503493
esv3569801 CNV loss 25503493
esv3575787 CNV gain 25503493
esv3575788 CNV gain 25503493
esv3575789 CNV gain 25503493
esv3602962 CNV loss 21293372
esv3602964 CNV loss 21293372
esv3602966 CNV loss 21293372
esv3602967 CNV loss 21293372
esv3602968 CNV loss 21293372
esv3602969 CNV loss 21293372
esv3602970 CNV loss 21293372
esv3602974 CNV loss 21293372
esv3602975 CNV gain 21293372
esv3602976 CNV loss 21293372
esv3602979 CNV loss 21293372
esv3602980 CNV loss 21293372
esv3602982 CNV loss 21293372
esv3602984 CNV loss 21293372
esv3602985 CNV loss 21293372
esv3602988 CNV loss 21293372
esv3602991 CNV loss 21293372
esv3894065 CNV loss 25118596
esv4777 CNV loss 18987735
esv6963 CNV loss 19470904
esv992191 CNV deletion 20482838
esv993008 CNV deletion 20482838
esv995521 CNV deletion 20482838
nsv1019140 CNV gain 25217958
nsv1019387 CNV gain 25217958
nsv1026744 CNV gain 25217958
nsv1029451 CNV loss 25217958
nsv1030184 CNV loss 25217958
nsv1074233 CNV deletion 25765185
nsv1074234 CNV deletion 25765185
nsv1114594 CNV deletion 24896259
nsv1117401 CNV tandem duplication 24896259
nsv1123861 CNV deletion 24896259
nsv1126049 CNV deletion 24896259
nsv1131837 CNV deletion 24896259
nsv1139326 CNV deletion 24896259
nsv1139822 CNV duplication 24896259
nsv1148331 CNV deletion 26484159
nsv1152187 CNV insertion 26484159
nsv1153533 CNV deletion 26484159
nsv292001 CNV deletion 16902084
nsv293053 CNV deletion 16902084
nsv436419 CNV deletion 17901297
nsv4586 CNV insertion 18451855
nsv4588 CNV deletion 18451855
nsv474278 CNV novel sequence insertion 20440878
nsv476552 CNV novel sequence insertion 20440878
nsv477493 CNV novel sequence insertion 20440878
nsv509943 OTHER sequence alteration 20534489
nsv513174 CNV loss 21212237
nsv521840 CNV loss 19592680
nsv525419 CNV loss 19592680
nsv526583 CNV gain 19592680
nsv596024 CNV loss 21841781
nsv596025 CNV loss 21841781
nsv818295 CNV loss 17921354
nsv819593 CNV gain 19587683
nsv821217 CNV deletion 20802225
nsv822813 CNV loss 20364138
nsv822814 CNV gain+loss 20364138
nsv830138 CNV gain 17160897
nsv955647 CNV deletion 24416366
nsv956381 CNV deletion 24416366
nsv958227 CNV deletion 24416366
nsv964107 CNV duplication 23825009
nsv964108 CNV duplication 23825009
nsv966334 CNV duplication 23825009
nsv966335 CNV duplication 23825009
nsv966375 CNV duplication 23825009
nsv966562 CNV deletion 23825009
nsv967846 CNV duplication 23825009
nsv980269 CNV duplication 23825009
nsv980270 CNV duplication 23825009
nsv980497 CNV deletion 23825009

Variation tolerance for MARCH1 Gene

Residual Variation Intolerance Score: 38.4% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for MARCH1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MARCH1 Gene

Disorders for MARCH1 Gene

Additional Disease Information for MARCH1

Genetic Association Database
Human Genome Epidemiology Navigator
ATLAS of Genetics and Cytogenetics in Oncology and Haematology

No disorders were found for MARCH1 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for MARCH1 Gene

Publications for MARCH1 Gene

  1. Interleukin-10-induced MARCH1 mediates intracellular sequestration of MHC class II in monocytes. (PMID: 18389477) Thibodeau J … Steimle V (European journal of immunology 2008) 3 4 22 58
  2. MHC class II stabilization at the surface of human dendritic cells is the result of maturation-dependent MARCH I down-regulation. (PMID: 18305173) De Gassart A … Gatti E (Proceedings of the National Academy of Sciences of the United States of America 2008) 3 4 22 58
  3. Downregulation of major histocompatibility complex class I by human ubiquitin ligases related to viral immune evasion proteins. (PMID: 14722266) Bartee E … Früh K (Journal of virology 2004) 2 3 4 58
  4. Transferability of type 2 diabetes implicated loci in multi-ethnic cohorts from Southeast Asia. (PMID: 21490949) Sim X … Tai ES (PLoS genetics 2011) 3 44 58
  5. Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58

Products for MARCH1 Gene

Sources for MARCH1 Gene

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