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Aliases for MAPT-AS1 Gene

Subcategory (RNA class) for MAPT-AS1 Gene

non-coding RNA

Quality Score for this RNA gene is

13

Aliases for MAPT-AS1 Gene

  • MAPT Antisense RNA 1 2 3 5
  • MAPT Antisense RNA 1 (Non-Protein Coding) 2 3

External Ids for MAPT-AS1 Gene

Previous GeneCards Identifiers for MAPT-AS1 Gene

  • GC17M043921
  • GC17M045843

Summaries for MAPT-AS1 Gene

GeneCards Summary for MAPT-AS1 Gene

MAPT-AS1 (MAPT Antisense RNA 1) is an RNA Gene, and is affiliated with the non-coding RNA class. Diseases associated with MAPT-AS1 include Parkinson Disease, Late-Onset.

Additional gene information for MAPT-AS1 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for MAPT-AS1 Gene

Genomics for MAPT-AS1 Gene

GeneHancer (GH) Regulatory Elements for MAPT-AS1 Gene

Promoters and enhancers for MAPT-AS1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH17J045893 Promoter/Enhancer 2 EPDnew Ensembl ENCODE 650.7 +0.4 382 2.9 HDGF ARNT SIN3A FEZF1 DMAP1 ZNF2 YY1 ZNF766 ZNF213 ZNF143 GC17P045896 MAPT-IT1 MAPT-AS1 MAPT LINC02210 MAPK8IP1P1 ENSG00000262372 KANSL1 ARL17A ARL17B
GH17J045873 Enhancer 0.7 FANTOM5 ENCODE 0.3 +21.8 21794 0.7 MEIS2 PKNOX1 POLR2A FOXP2 RCOR1 TRIM28 LINC02210 SPPL2C MAPT MAPT-AS1 PIRC95
GH17J045852 Enhancer 0.7 ENCODE 0.3 +42.8 42760 0.2 ELF3 CTCF AHR RB1 RAD21 TEAD3 ZFHX2 GLIS2 EGR1 SMC3 LINC02210 SPPL2C MAPT MAPT-AS1 PIRC95
GH17J045834 Enhancer 0.8 ENCODE 0.2 +63.3 63320 0.2 HDGF ARNT INSM2 ZNF2 ZSCAN9 RAD21 ZNF121 ZNF143 RCOR1 SMARCA5 LOC105371801 SPPL2C CRHR1 MAPT-AS1 LINC02210-CRHR1 PIRC95
GH17J045832 Enhancer 0.7 ENCODE 0.2 +63.1 63130 0.1 CTCF TEAD4 ZNF2 ZSCAN9 RAD21 ZNF143 RCOR1 KLF8 CHD2 ZNF362 LOC105371801 SPPL2C CRHR1 MAPT-AS1 LINC02210-CRHR1 PIRC95
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MAPT-AS1 on UCSC Golden Path with GeneCards custom track

Genomic Locations for MAPT-AS1 Gene

Genomic Locations for MAPT-AS1 Gene
chr17:45,799,390-45,895,630
(GRCh38/hg38)
Size:
96,241 bases
Orientation:
Minus strand
chr17:43,920,722-43,972,966
(GRCh37/hg19)
Size:
52,245 bases
Orientation:
Minus strand

Genomic View for MAPT-AS1 Gene

Genes around MAPT-AS1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MAPT-AS1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MAPT-AS1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MAPT-AS1 Gene

Function for MAPT-AS1 Gene

Phenotypes From GWAS Catalog for MAPT-AS1 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for MAPT-AS1 Gene

Localization for MAPT-AS1 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for MAPT-AS1 Gene

Pathways & Interactions for MAPT-AS1 Gene

SuperPathways for MAPT-AS1 Gene

No Data Available

Interacting Proteins for MAPT-AS1 Gene

Gene Ontology (GO) - Biological Process for MAPT-AS1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0031047 gene silencing by RNA IMP 27336847
GO:1905642 negative regulation of DNA methylation IMP 27336847
genes like me logo Genes that share ontologies with MAPT-AS1: view

No data available for Pathways by source and SIGNOR curated interactions for MAPT-AS1 Gene

Drugs & Compounds for MAPT-AS1 Gene

No Compound Related Data Available

Transcripts for MAPT-AS1 Gene

mRNA/cDNA for MAPT-AS1 Gene

(2) Additional mRNA sequences :
(4) Ensembl transcripts including schematic representations, and UCSC links where relevant :
(9) RNA Central transcripts :

Unigene Clusters for MAPT-AS1 Gene

MAPT antisense RNA 1:
Representative Sequences:

Alternative Splicing Database (ASD) splice patterns (SP) for MAPT-AS1 Gene

No ASD Table

Relevant External Links for MAPT-AS1 Gene

GeneLoc Exon Structure for
MAPT-AS1
ECgene alternative splicing isoforms for
MAPT-AS1

Expression for MAPT-AS1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for MAPT-AS1 Gene

mRNA differential expression in normal tissues according to GTEx for MAPT-AS1 Gene

This gene is overexpressed in Testis (x5.4), Brain - Hypothalamus (x5.1), and Brain - Amygdala (x4.5).

SOURCE GeneReport for Unigene cluster for MAPT-AS1 Gene:

Hs.666302
genes like me logo Genes that share expression patterns with MAPT-AS1: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for MAPT-AS1 Gene

Orthologs for MAPT-AS1 Gene

Evolution for MAPT-AS1 Gene

ENSEMBL:
Gene Tree for MAPT-AS1 (if available)
TreeFam:
Gene Tree for MAPT-AS1 (if available)

No data available for Orthologs for MAPT-AS1 Gene

Paralogs for MAPT-AS1 Gene

No data available for Paralogs for MAPT-AS1 Gene

Variants for MAPT-AS1 Gene

Sequence variations from dbSNP and Humsavar for MAPT-AS1 Gene

SNP ID Clin Chr 17 pos Variation AA Info Type
rs1019760885 uncertain-significance, MAPT-Related Spectrum Disorders 45,894,678(-) G/T intron_variant
rs1044833240 uncertain-significance, MAPT-Related Spectrum Disorders 45,894,390(-) G/A intron_variant
rs11575895 benign, MAPT-Related Spectrum Disorders 45,894,419(-) A/G intron_variant
rs144722105 benign, MAPT-Related Spectrum Disorders 45,894,660(-) CCC/CC intron_variant
rs62056779 benign, MAPT-Related Spectrum Disorders 45,894,571(-) C/A intron_variant

Structural Variations from Database of Genomic Variants (DGV) for MAPT-AS1 Gene

Variant ID Type Subtype PubMed ID
dgv3178n100 CNV gain 25217958
esv2662666 CNV deletion 23128226
esv2669509 CNV deletion 23128226
esv2762433 CNV gain+loss 21179565
esv3554471 CNV deletion 23714750
esv3582706 CNV loss 25503493
esv3640674 CNV loss 21293372
nsv1146669 OTHER inversion 26484159
nsv518110 CNV loss 19592680
nsv522515 CNV loss 19592680
nsv575141 CNV loss 21841781
nsv833460 CNV loss 17160897
nsv953909 CNV deletion 24416366

Additional Variant Information for MAPT-AS1 Gene

SNPedia medical, phenotypic, and genealogical associations of SNPs for
MAPT-AS1

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Variation tolerance for MAPT-AS1 Gene

Disorders for MAPT-AS1 Gene

MalaCards: The human disease database

(1) MalaCards diseases for MAPT-AS1 Gene - From: LncRNADisease and DISEASES

Disorder Aliases PubMed IDs
parkinson disease, late-onset
  • pd
- elite association - COSMIC cancer census association via MalaCards

Additional Disease Information for MAPT-AS1

genes like me logo Genes that share disorders with MAPT-AS1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MAPT-AS1 Gene

Publications for MAPT-AS1 Gene

  1. Role of the Long Non-Coding RNA MAPT-AS1 in Regulation of Microtubule Associated Protein Tau (MAPT) Expression in Parkinson's Disease. (PMID: 27336847) Coupland KG … Kwok JB (PloS one 2016) 2 3 58
  2. Genetic variants associated with idiopathic pulmonary fibrosis susceptibility and mortality: a genome-wide association study. (PMID: 24429156) Noth I … Garcia JGN (The Lancet. Respiratory medicine 2013) 3 58
  3. Six novel susceptibility Loci for early-onset androgenetic alopecia and their unexpected association with common diseases. (PMID: 22693459) Li R … Richards JB (PLoS genetics 2012) 3 58
  4. Web-based genome-wide association study identifies two novel loci and a substantial genetic component for Parkinson's disease. (PMID: 21738487) Do CB … Eriksson N (PLoS genetics 2011) 3 58
  5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. (PMID: 12477932) Strausberg RL … Mammalian Gene Collection Program Team (Proceedings of the National Academy of Sciences of the United States of America 2002) 3 58

Products for MAPT-AS1 Gene

Sources for MAPT-AS1 Gene

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