Aliases for MAP7 Gene
External Ids for MAP7 Gene
Previous GeneCards Identifiers for MAP7 Gene
The product of this gene is a microtubule-associated protein that is predominantly expressed in cells of epithelial origin. Microtubule-associated proteins are thought to be involved in microtubule dynamics, which is essential for cell polarization and differentiation. This protein has been shown to be able to stabilize microtubules, and may serve to modulate microtubule functions. Studies of the related mouse protein also suggested an essential role in microtubule function required for spermatogenesis. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
GeneCards Summary for MAP7 Gene
MAP7 (Microtubule Associated Protein 7) is a Protein Coding gene. Diseases associated with MAP7 include Esophagus Adenocarcinoma. Gene Ontology (GO) annotations related to this gene include receptor binding and structural molecule activity. An important paralog of this gene is MAP7D1.
UniProtKB/Swiss-Prot for MAP7 Gene
Microtubule-stabilizing protein that may play an important role during reorganization of microtubules during polarization and differentiation of epithelial cells. Associates with microtubules in a dynamic manner. May play a role in the formation of intercellular contacts. Colocalization with TRPV4 results in the redistribution of TRPV4 toward the membrane and may link cytoskeletal microfilaments.