Aliases for MAP1LC3B2 Gene
External Ids for MAP1LC3B2 Gene
Previous GeneCards Identifiers for MAP1LC3B2 Gene
GeneCards Summary for MAP1LC3B2 Gene
MAP1LC3B2 (Microtubule Associated Protein 1 Light Chain 3 Beta 2) is a Protein Coding gene. Among its related pathways are Ferroptosis. Gene Ontology (GO) annotations related to this gene include microtubule binding. An important paralog of this gene is MAP1LC3B.
UniProtKB/Swiss-Prot Summary for MAP1LC3B2 Gene
Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation (By similarity).