The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially ... See more...

Aliases for MAOB Gene

Aliases for MAOB Gene

  • Monoamine Oxidase B 2 3 5
  • Amine Oxidase [Flavin-Containing] B 3 4
  • Monoamine Oxidase Type B 3 4
  • EC 1.4.3.4 4 51
  • MAO-B 3 4
  • Adrenalin Oxidase 3
  • Tyramine Oxidase 3
  • MAO, Platelet 3
  • MAO, Brain 3
  • EC 1.4.3 51
  • MAOB 5

External Ids for MAOB Gene

Previous GeneCards Identifiers for MAOB Gene

  • GC0XM041637
  • GC0XM041886
  • GC0XM042452
  • GC0XM042671
  • GC0XM043383
  • GC0XM043510
  • GC0XM043625
  • GC0XM041355

Summaries for MAOB Gene

Entrez Gene Summary for MAOB Gene

  • The protein encoded by this gene belongs to the flavin monoamine oxidase family. It is a enzyme located in the mitochondrial outer membrane. It catalyzes the oxidative deamination of biogenic and xenobiotic amines and plays an important role in the metabolism of neuroactive and vasoactive amines in the central nervous sysytem and peripheral tissues. This protein preferentially degrades benzylamine and phenylethylamine. [provided by RefSeq, Jul 2008]

GeneCards Summary for MAOB Gene

MAOB (Monoamine Oxidase B) is a Protein Coding gene. Diseases associated with MAOB include Norrie Disease and Pathological Gambling. Among its related pathways are Tyrosine metabolism and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. Gene Ontology (GO) annotations related to this gene include protein homodimerization activity and electron transfer activity. An important paralog of this gene is MAOA.

UniProtKB/Swiss-Prot Summary for MAOB Gene

  • Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.

Tocris Summary for MAOB Gene

  • Monoamine Oxidases (MAO) catalyze the oxidation of monoamines such as dopamine, serotonin and adrenalin. They are found bound to the outer membrane of mitochondria in most cell types in the body. Two subtypes of MAO have been identified: MAO-A and MAO-B.

Gene Wiki entry for MAOB Gene

No data available for CIViC Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MAOB Gene

Genomics for MAOB Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MAOB Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH0XJ043877 Promoter/Enhancer 1.5 EPDnew Ensembl ENCODE 600.7 +1.9 1859 5.6 GATAD2A REST RCOR2 RBFOX2 RXRB IRF2 BRD4 SP1 CEBPA SCRT2 MAOB lnc-NDP-1 RF00017-8347 MAOA
GH0XJ043860 Enhancer 0.8 Ensembl ENCODE 13.9 +20.8 20849 2.4 SP1 SOX13 RFX1 FOXA2 JUND RAD21 FOSL2 HNF4A RXRA NFIA MAOB RF00017-8347 lnc-NDP-1 MAOA
GH0XJ044312 Enhancer 1.3 FANTOM5 Ensembl ENCODE 6.5 -431.8 -431796 4.1 LEF1 IKZF1 JUND MTA2 PHF21A PKNOX1 ZNF24 REST BRD9 DPF2 EFHC2 KDM6A MAOB RRM2P3 RF00017-8348 piR-57460-717 NDP
GH0XJ042939 Enhancer 1.1 FANTOM5 Ensembl ENCODE dbSUPER 5 +937.3 937250 11.2 TCF12 IKZF2 YY1 ARID3A DPF2 RUNX3 CBFB EBF1 JUN POLR2A LOC107985717 MAOB HSALNG0137516 LOC105373188 lnc-PPP1R2C-2 PPP1R2C MAOA
GH0XJ042933 Enhancer 1 Ensembl ENCODE dbSUPER 5 +948.0 948049 2.4 STAT3 RELA IKZF2 TRIM22 EED DPF2 RELB RUNX3 BCLAF1 CBFB MAOB HSALNG0137516 LOC105373188 LOC107985717 PPP1R2C MAOA
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MAOB on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for MAOB

Top Transcription factor binding sites by QIAGEN in the MAOB gene promoter:
  • AP-1
  • AREB6
  • ATF-2
  • c-Fos
  • c-Jun
  • Sox5

Genomic Locations for MAOB Gene

Genomic Locations for MAOB Gene
chrX:43,766,610-43,882,450
(GRCh38/hg38)
Size:
115,841 bases
Orientation:
Minus strand
chrX:43,625,857-43,741,721
(GRCh37/hg19)
Size:
115,865 bases
Orientation:
Minus strand

Genomic View for MAOB Gene

Genes around MAOB on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MAOB Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MAOB Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MAOB Gene

Proteins for MAOB Gene

  • Protein details for MAOB Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    P27338-AOFB_HUMAN
    Recommended name:
    Amine oxidase [flavin-containing] B
    Protein Accession:
    P27338
    Secondary Accessions:
    • B2R6R3
    • B7Z5H3
    • D3DWC3
    • Q7Z6S2

    Protein attributes for MAOB Gene

    Size:
    520 amino acids
    Molecular mass:
    58763 Da
    Cofactor:
    Name=FAD; Xref=ChEBI:CHEBI:57692;
    Quaternary structure:
    • Monomer, homo- or heterodimer (containing two subunits of similar size). Each subunit contains a covalently bound flavin. Enzymatically active as monomer (By similarity).

    Three dimensional structures from OCA and Proteopedia for MAOB Gene

    Alternative splice isoforms for MAOB Gene

    UniProtKB/Swiss-Prot:

neXtProt entry for MAOB Gene

Selected DME Specific Peptides for MAOB Gene

P27338:
  • AGERAARE
  • EPESVDVPA
  • DLGGSYVGPTQN
  • SATALGFLAHK
  • GCYTTYFPPGI
  • RVPLGSVIKCIVYYK
  • RNQKVKY
  • RVGGRTYT
  • GPTQNRILR
  • EIPSDAPWKAPLAEEWD
  • WSGYMEGAV
  • LPSVPGLL
  • YEAKYVISA
  • VSALWFLWYVKQCGGTTRI
  • KELGLETYKVNEVERLIH
  • FPPVWNP
  • FAGTETAT
  • LGDRVKL
  • VLEARDRVGGRT
  • IHHVKGKSYPFRGPFPP
  • LFVNLCVTAE
  • RLTKEERL
  • HEVSALWFLWYV
  • PVHYEEKNWC
  • CELYAKVLGS
  • DDMGREIPSDAPWKAPLAE
  • IWQSEPES
  • VGGRTYTLRNQ
  • YVISAIPP

Post-translational modifications for MAOB Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MAOB Gene

Domains & Families for MAOB Gene

Gene Families for MAOB Gene

Human Protein Atlas (HPA):
  • Enzymes
  • FDA approved drug targets
  • Predicted membrane proteins

Protein Domains for MAOB Gene

InterPro:
Blocks:
  • Flavin-containing amine oxidase signature
ProtoNet:

Suggested Antigen Peptide Sequences for MAOB Gene

GenScript: Design optimal peptide antigens:
  • Monoamine oxidase type B (AOFB_HUMAN)
  • cDNA FLJ51821, highly similar to Amine oxidase (flavin-containing) B (EC 1.4.3.4) (B7Z242_HUMAN)
  • cDNA FLJ52418, highly similar to Amine oxidase (flavin-containing) B (EC 1.4.3.4) (B7Z5H3_HUMAN)
  • Monoamine oxidase B (Q8TBI1_HUMAN)

Graphical View of Domain Structure for InterPro Entry

P27338

UniProtKB/Swiss-Prot:

AOFB_HUMAN :
  • Belongs to the flavin monoamine oxidase family.
Family:
  • Belongs to the flavin monoamine oxidase family.
genes like me logo Genes that share domains with MAOB: view

Function for MAOB Gene

Molecular function for MAOB Gene

UniProtKB/Swiss-Prot Function:
Catalyzes the oxidative deamination of biogenic and xenobiotic amines and has important functions in the metabolism of neuroactive and vasoactive amines in the central nervous system and peripheral tissues. MAOB preferentially degrades benzylamine and phenylethylamine.
UniProtKB/Swiss-Prot CatalyticActivity:
Reaction=a secondary aliphatic amine + H2O + O2 = a primary amine + an aldehyde + H2O2; Xref=Rhea:RHEA:26414, ChEBI:CHEBI:15377, ChEBI:CHEBI:15379, ChEBI:CHEBI:16240, ChEBI:CHEBI:17478, ChEBI:CHEBI:58855, ChEBI:CHEBI:65296; EC=1.4.3.4;.
GENATLAS Biochemistry:
monoamine oxidase B

Enzyme Numbers (IUBMB) for MAOB Gene

Phenotypes From GWAS Catalog for MAOB Gene

Gene Ontology (GO) - Molecular Function for MAOB Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 28514442
GO:0008131 primary amine oxidase activity IEA --
GO:0009055 electron transfer activity TAS 8602220
GO:0016491 oxidoreductase activity IEA --
GO:0042802 identical protein binding IEA --
genes like me logo Genes that share ontologies with MAOB: view
genes like me logo Genes that share phenotypes with MAOB: view

Animal Models for MAOB Gene

MGI Knock Outs for MAOB:
  • Maob Maob<tm1Shih>

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MAOB

No data available for Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for MAOB Gene

Localization for MAOB Gene

Subcellular locations from UniProtKB/Swiss-Prot for MAOB Gene

Mitochondrion outer membrane. Single-pass type IV membrane protein. Cytoplasmic side.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MAOB gene
Compartment Confidence
mitochondrion 5
nucleus 3
cytosol 3
plasma membrane 2
extracellular 2
cytoskeleton 2
peroxisome 2
endoplasmic reticulum 2
lysosome 2
endosome 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for MAOB Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005739 mitochondrion IEA,HDA 20833797
GO:0005740 mitochondrial envelope TAS 7063850
GO:0005741 mitochondrial outer membrane TAS 24252804
GO:0016020 membrane IEA --
GO:0016021 integral component of membrane IEA --
genes like me logo Genes that share ontologies with MAOB: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for MAOB Gene

Pathways & Interactions for MAOB Gene

genes like me logo Genes that share pathways with MAOB: view

SIGNOR curated interactions for MAOB Gene

Is activated by:
Is inactivated by:

Gene Ontology (GO) - Biological Process for MAOB Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0009636 response to toxic substance IEA --
GO:0010044 response to aluminum ion IEA --
GO:0010269 response to selenium ion IEA --
GO:0014063 negative regulation of serotonin secretion IEA --
GO:0021762 substantia nigra development HEP 22926577
genes like me logo Genes that share ontologies with MAOB: view

Drugs & Compounds for MAOB Gene

(129) Drugs for MAOB Gene - From: DrugBank, ApexBio, DGIdb, HMDB, Tocris, and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Methamphetamine Approved, Illicit Pharma Target, inhibitor, antagonist 242
Moclobemide Approved, Investigational Pharma Target, Target, Enzyme, antagonist, inhibitor 7
Phenelzine Approved Pharma Target, Enzyme, antagonist, substrate, inhibitor 10
Rasagiline Approved Pharma Target, inhibitor 59
Selegiline Approved, Investigational, Vet_approved Pharma Target, inhibitor 28

(87) Additional Compounds for MAOB Gene - From: HMDB, Novoseek, and Tocris

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
1-Methylhistamine
  • 1-Methyl-1H-imidazole-4-ethanamine
  • 1-Methyl-4-(2-aminoethyl)imidazole
  • 3-Methylhistamine
  • 4-(1-Aminoethyl)-1-methyl-1H-imidazole
  • Methylhistamine
501-75-7
1-Phenylethylamine
  • 1-amino-1-Phenylethane
  • 1-Phenethylamine
  • alpha-Aminoethylbenzene
  • alpha-Methylbenzenemethanamine
  • alpha-Methylbenzylamine
98-84-0
3,4-Dihydroxymandelaldehyde
  • 3,4-Dihydroxymandelic aldehyde
  • 3,4-Dihydroxyphenylglycolaldehyde
  • 3,4-Dihydroxyphenylglycolic aldehyde
  • alpha,3,4-Trihydroxybenzeneacetaldehyde
  • alpha,3,4-Trihydroxyphenylacetaldehyde
13023-73-9
3,4-Dihydroxyphenylacetaldehyde
  • 2-(3,4-Dihydroxyphenyl)ethanal
  • DOPAL
  • Protocatechuatealdehyde
  • 3,4-Dihydroxy-benzeneacetaldehyde
  • DHPAA aldehyde
5707-55-1
3-Hydroxykynurenamine

(5) Tocris Compounds for MAOB Gene

Compound Action Cas Number
(R)-(-)-Deprenyl hydrochloride MAO-B inhibitor 14611-52-0
Bifemelane hydrochloride MAO-A and MAO-B inhibitor 62232-46-6
Lazabemide hydrochloride Selective MAO-B inhibitor 103878-83-7
Pirlindole mesylate MAO-A inhibitor 207572-66-5
Tetrindole mesylate MAO-A inhibitor 170964-68-8

(13) ApexBio Compounds for MAOB Gene

Compound Action Cas Number
2-BFI hydrochloride
BU 224 hydrochloride Antagonist of I2 Imidazoline receptor,potent and selective 205437-64-5
BU 226 hydrochloride Ligand at I2 imidazoline sites,high affinity and selectivity 1186195-56-1
BU 239 hydrochloride Ligand of imidazoline I2 receptor,potent and selective 1217041-98-9
Paeonol MAO inhibitor;multi-functional phenolic compound 552-41-0
Pirlindole mesylate 207572-66-5
Procarbazine HCl Antineoplastic chemotherapy drug 366-70-1
Rasagiline Mesylate Irreversible MAO-B inhibitor 161735-79-1
RS 45041-190 hydrochloride 204274-74-8
Safinamide Mesylate MAO-B inhibitor,potent,selective and reversible 202825-46-5
Sennoside A Irritant laxative;mild MAO inhibitor 81-27-6
Tetrindole mesylate 170964-68-8
Tranylcypromine hydrochloride 1986-47-6
genes like me logo Genes that share compounds with MAOB: view

Transcripts for MAOB Gene

mRNA/cDNA for MAOB Gene

1 REFSEQ mRNAs :
12 NCBI additional mRNA sequence :
3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MAOB

Alternative Splicing Database (ASD) splice patterns (SP) for MAOB Gene

No ASD Table

Relevant External Links for MAOB Gene

GeneLoc Exon Structure for
MAOB

Expression for MAOB Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MAOB Gene

Protein differential expression in normal tissues from HIPED for MAOB Gene

This gene is overexpressed in Spinal cord (7.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MAOB Gene



Protein tissue co-expression partners for MAOB Gene

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MAOB

SOURCE GeneReport for Unigene cluster for MAOB Gene:

Hs.654473

Evidence on tissue expression from TISSUES for MAOB Gene

  • Liver(4.7)
  • Nervous system(4.6)
  • Heart(3.8)
  • Adrenal gland(3.1)
  • Blood(3)
  • Kidney(3)
  • Muscle(3)
  • Intestine(2.7)
  • Skin(2.6)
  • Eye(2.4)
  • Pancreas(2.3)
  • Stomach(2.2)
  • Lung(2.1)
genes like me logo Genes that share expression patterns with MAOB: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for MAOB Gene

Orthologs for MAOB Gene

This gene was present in the common ancestor of animals and fungi.

Orthologs for MAOB Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia MAOB 30 31
  • 99.29 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia MAOB 30 31
  • 91.79 (n)
OneToOne
Cow
(Bos Taurus)
Mammalia MAOB 30 31
  • 90.64 (n)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia MAOB 31
  • 88 (a)
OneToOne
Mouse
(Mus musculus)
Mammalia Maob 30 17 31
  • 87.58 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Maob 30
  • 86.64 (n)
Platypus
(Ornithorhynchus anatinus)
Mammalia MAOB 31
  • 75 (a)
OneToOne
Chicken
(Gallus gallus)
Aves MAOB 30 31
  • 74.57 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia MAOB 31
  • 73 (a)
OneToOne
Tropical Clawed Frog
(Silurana tropicalis)
Amphibia LOC100494267 30
  • 72.96 (n)
Zebrafish
(Danio rerio)
Actinopterygii mao 30 31
  • 68.53 (n)
OneToMany
Rainbow Trout
(Oncorhynchus mykiss)
Actinopterygii Omy.11797 30
Bread mold
(Neurospora crassa)
Ascomycetes NCU05933 30
  • 42.47 (n)
Species where no ortholog for MAOB was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Squirt (Ciona savignyi)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for MAOB Gene

ENSEMBL:
Gene Tree for MAOB (if available)
TreeFam:
Gene Tree for MAOB (if available)
Aminode:
Evolutionary constrained regions (ECRs) for MAOB: view image

Paralogs for MAOB Gene

Paralogs for MAOB Gene

(1) SIMAP similar genes for MAOB Gene using alignment to 4 proteins:

  • AOFB_HUMAN
  • B7Z242_HUMAN
  • B7Z5H3_HUMAN
  • Q8TBI1_HUMAN
genes like me logo Genes that share paralogs with MAOB: view

Variants for MAOB Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MAOB Gene

SNP ID Clinical significance and condition Chr 0X pos Variation AA Info Type
711252 Benign: not provided 43,843,727(-) C/A SYNONYMOUS_VARIANT
713666 Likely Benign: not provided 43,775,281(-) T/C INTRON_VARIANT
716258 Benign: not provided 43,793,510(-) T/C SYNONYMOUS_VARIANT
717563 Benign: not provided 43,802,246(-) T/C SYNONYMOUS_VARIANT
728050 Likely Benign: not provided 43,767,565(-) G/A SYNONYMOUS_VARIANT

Additional dbSNP identifiers (rs#s) for MAOB Gene

Variation tolerance for MAOB Gene

Residual Variation Intolerance Score: 16% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 0.71; 15.00% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for MAOB Gene

Human Gene Mutation Database (HGMD)
MAOB
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MAOB

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for MAOB Gene

Disorders for MAOB Gene

MalaCards: The human disease database

(46) MalaCards diseases for MAOB Gene - From: DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
norrie disease
  • nd
pathological gambling
  • compulsive gambling
antisocial personality disorder
  • asocial personality
post-traumatic stress disorder
  • traumatic neurosis
parkinson disease, late-onset
  • pd
- elite association - COSMIC cancer census association via MalaCards
Search MAOB in MalaCards View complete list of genes associated with diseases

Genatlas disease for MAOB Gene

monoamine oxidase deficiency

Additional Disease Information for MAOB

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
genes like me logo Genes that share disorders with MAOB: view

No data available for UniProtKB/Swiss-Prot for MAOB Gene

Publications for MAOB Gene

  1. A common variant in DRD3 gene is associated with risperidone-induced extrapyramidal symptoms. (PMID: 19506579) Gassó P … Lafuente A (The pharmacogenomics journal 2009) 3 23 41
  2. Polymorphisms in SLC6A4, PAH, GABRB3, and MAOB and modification of psychotic disorder features. (PMID: 19268543) Bergen SE … Kendler KS (Schizophrenia research 2009) 3 23 41
  3. Negative emotionality: monoamine oxidase B gene variants modulate personality traits in healthy humans. (PMID: 19657584) Dlugos AM … de Wit H (Journal of neural transmission (Vienna, Austria : 1996) 2009) 3 23 41
  4. Gene-gene interaction between FGF20 and MAOB in Parkinson disease. (PMID: 18205889) Gao X … Martin ER (Annals of human genetics 2008) 3 23 41
  5. Association of A/G polymorphism in intron 13 of the monoamine oxidase B gene with schizophrenia in a Spanish population. (PMID: 18832861) Gassó P … Lafuente A (Neuropsychobiology 2008) 3 23 41

Products for MAOB Gene

Sources for MAOB Gene