Aliases for MAN2C1 Gene
External Ids for MAN2C1 Gene
Previous HGNC Symbols for MAN2C1 Gene
Previous GeneCards Identifiers for MAN2C1 Gene
GeneCards Summary for MAN2C1 Gene
MAN2C1 (Mannosidase Alpha Class 2C Member 1) is a Protein Coding gene. Diseases associated with MAN2C1 include Cholestasis, Intrahepatic, Of Pregnancy 3 and Mannosidosis, Alpha B, Lysosomal. Among its related pathways are Glycosaminoglycan metabolism and Metabolism. Gene Ontology (GO) annotations related to this gene include carbohydrate binding and alpha-mannosidase activity. An important paralog of this gene is MAN2A2.
UniProtKB/Swiss-Prot Summary for MAN2C1 Gene
Cleaves alpha 1,2-, alpha 1,3-, and alpha 1,6-linked mannose residues from glycoproteins. Involved in the degradation of free oligosaccharides in the cytoplasm.
Glycosylases are a group of enzymes that includes glucosidases, mannosidases and heparanases. There are two glucosidase subtypes, both found in the gut. They hydrolyze terminal (1,4)alpha-glucosidic linkages and (1,6)beta-glucosidic linkages, liberating alpha-glucose and beta-glucose.