The protein encoded by this gene is a member of the membrane-associated guanylate kinase homologue (MAGUK) family. MAGUK proteins participate in the assembly of multiprotein complexes on the inner surface of the plasma membrane at regions of cell-cell contact. The product of this gene may play a role as scaffolding protein at cell-cell junctions. Alternatively spliced transcrip... See more...

Aliases for MAGI1 Gene

Aliases for MAGI1 Gene

  • Membrane Associated Guanylate Kinase, WW And PDZ Domain Containing 1 2 3 5
  • BAI1-Associated Protein 1 2 3 4
  • MAGI-1 2 3 4
  • TNRC19 2 3 4
  • AIP3 2 3 4
  • BAP1 2 3 4
  • WWP3 2 3 4
  • Membrane-Associated Guanylate Kinase, WW And PDZ Domain-Containing Protein 1 3 4
  • Membrane-Associated Guanylate Kinase Inverted 1 3 4
  • Trinucleotide Repeat-Containing Gene 19 Protein 3 4
  • Atrophin-1-Interacting Protein 3 3 4
  • WW Domain-Containing Protein 3 3 4
  • BAIAP1 3 4
  • AIP-3 3 4
  • BAP-1 3 4
  • MAGI-1b 3
  • Magi1d 3
  • MAGI1 5

External Ids for MAGI1 Gene

Previous HGNC Symbols for MAGI1 Gene

  • BAIAP1

Previous GeneCards Identifiers for MAGI1 Gene

  • GC06M154757
  • GC06M154818
  • GC03M065318

Summaries for MAGI1 Gene

Entrez Gene Summary for MAGI1 Gene

  • The protein encoded by this gene is a member of the membrane-associated guanylate kinase homologue (MAGUK) family. MAGUK proteins participate in the assembly of multiprotein complexes on the inner surface of the plasma membrane at regions of cell-cell contact. The product of this gene may play a role as scaffolding protein at cell-cell junctions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]

GeneCards Summary for MAGI1 Gene

MAGI1 (Membrane Associated Guanylate Kinase, WW And PDZ Domain Containing 1) is a Protein Coding gene. Diseases associated with MAGI1 include Cervical Large Cell Neuroendocrine Carcinoma and Microscopic Colitis. Among its related pathways are Pathways Affected in Adenoid Cystic Carcinoma and G-protein signaling_H-RAS regulation pathway. Gene Ontology (GO) annotations related to this gene include protein C-terminus binding and alpha-actinin binding. An important paralog of this gene is MAGI2.

UniProtKB/Swiss-Prot Summary for MAGI1 Gene

  • May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity).

Gene Wiki entry for MAGI1 Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MAGI1 Gene

Genomics for MAGI1 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MAGI1 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03J066035 Promoter/Enhancer 2.4 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 254.4 +1.1 1077 5.3 ZNF600 SSRP1 ZMYM3 POLR2A CHD4 ZBTB10 YY1 ZNF341 HOMEZ CTCF MAGI1 LOC105377128 lnc-SLC25A26-1 HSALNG0026621
GH03J065594 Promoter/Enhancer 1.8 EPDnew Ensembl ENCODE CraniofacialAtlas 255.6 +442.4 442352 3.9 POLR2A SIN3A YY1 PRDM6 TAF1 GLIS1 L3MBTL2 EGR1 SP1 GATA2 MAGI1 lnc-SLC25A26-9 piR-41306-185 ADAMTS9
GH03J065400 Promoter/Enhancer 1.4 EPDnew Ensembl ENCODE dbSUPER 250 +637.3 637283 3 ZNF600 JUND ATF2 SIN3A MAFK ZNF629 EGR2 RAD21 POLR2A ZFHX2 HSALNG0026608 MAGI1 HSALNG0026607 5MWI_A-108 ADAMTS9
GH03J065907 Promoter/Enhancer 0.8 EPDnew Ensembl 250.1 +131.2 131217 1 CTCF RFX1 RAD21 YY1 MAGI1 MAGI1-AS1 RF00017-3640 HSALNG0026614 MAGI1-IT1
GH03J065951 Promoter/Enhancer 1.8 FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 13.2 +84.5 84465 5.8 SSRP1 JUND ATF3 POLR2A CHD4 YY1 ZNF217 HOMEZ MBD2 ELF1 HSALNG0026614 MAGI1-IT1 MAGI1 RF00017-3640
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MAGI1 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for MAGI1

Top Transcription factor binding sites by QIAGEN in the MAGI1 gene promoter:
  • c-Rel
  • GATA-1
  • NF-kappaB
  • NF-kappaB1
  • NF-kappaB2
  • STAT1
  • STAT1alpha
  • STAT1beta
  • STAT2
  • TGIF

Genomic Locations for MAGI1 Gene

Latest Assembly
chr3:65,353,525-66,038,918
(GRCh38/hg38)
Size:
685,394 bases
Orientation:
Minus strand

Previous Assembly
chr3:65,339,201-66,024,593
(GRCh37/hg19 by Entrez Gene)
Size:
685,393 bases
Orientation:
Minus strand

chr3:65,339,200-66,024,509
(GRCh37/hg19 by Ensembl)
Size:
685,310 bases
Orientation:
Minus strand

Alternative Locations (GRCh38/hg38)

  • chr3(PATCHES):14,787-15,718 (-)

Genomic View for MAGI1 Gene

Genes around MAGI1 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MAGI1 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MAGI1 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MAGI1 Gene

Proteins for MAGI1 Gene

  • Protein details for MAGI1 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q96QZ7-MAGI1_HUMAN
    Recommended name:
    Membrane-associated guanylate kinase, WW and PDZ domain-containing protein 1
    Protein Accession:
    Q96QZ7
    Secondary Accessions:
    • A8K188
    • O00309
    • O43863
    • O75085
    • Q96QZ8
    • Q96QZ9

    Protein attributes for MAGI1 Gene

    Size:
    1491 amino acids
    Molecular mass:
    164581 Da
    Quaternary structure:
    • Interacts through its WW 2 domain with SYNPO and through its PDZ 5 domain with ACTN4 (PubMed:12042308). Interacts with cytoplasmic domain of ADGRB1 (PubMed:9647739). Interacts via its WW domains with DRPLA (PubMed:9647693). Interacts with ESAM, LRP2 and CXADR (By similarity). May interact with CTNNB1 (By similarity). Interacts through its PDZ 1 domain with NET1 (By similarity). Interacts with ASIC3 and AMOT (PubMed:15317815, PubMed:16043488). Interacts with FCHSD2 (PubMed:14627983). Interacts with IGSF5/JAM4 and through its PDZ 2 and 3 domains with NPHS1 forming a tripartite complex (By similarity) (PubMed:12773569). Interacts with DDN (PubMed:16751601). Isoform 3 (via PDZ domain) interacts with RAPGEF2 (PubMed:11168587). Interacts with DLL1 (By similarity). Interacts with KCNJ10 and possibly with KCNJ10/KCNJ16 heterodimer; this interaction may facilitate KCNJ10/KCNJ16 potassium channel expression at the basolateral membrane in kidney tubular cells. Interacts with PRRG4 (via cytoplasmic domain) (PubMed:23873930).

    Three dimensional structures from OCA and Proteopedia for MAGI1 Gene

    Alternative splice isoforms for MAGI1 Gene

neXtProt entry for MAGI1 Gene

Post-translational modifications for MAGI1 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for MAGI1 Gene

Domains & Families for MAGI1 Gene

Gene Families for MAGI1 Gene

HGNC:
Human Protein Atlas (HPA):
  • Cancer-related genes
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for MAGI1 Gene

Suggested Antigen Peptide Sequences for MAGI1 Gene

GenScript: Design optimal peptide antigens:
  • WW domain-containing protein 3 (MAGI1_HUMAN)
  • Membrane associated guanylate kinase, WW and PDZ domain containing 1 (Q5T4Y8_HUMAN)
genes like me logo Genes that share domains with MAGI1: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MAGI1 Gene

Function for MAGI1 Gene

Molecular function for MAGI1 Gene

UniProtKB/Swiss-Prot Function:
May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity).

Phenotypes From GWAS Catalog for MAGI1 Gene

Gene Ontology (GO) - Molecular Function for MAGI1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0000166 nucleotide binding IEA --
GO:0005515 protein binding IEA,IPI 9647693
GO:0005524 ATP binding IEA --
GO:0008022 protein C-terminus binding TAS 9647739
GO:0051393 alpha-actinin binding IPI 16464232
genes like me logo Genes that share ontologies with MAGI1: view
genes like me logo Genes that share phenotypes with MAGI1: view

Animal Models for MAGI1 Gene

MGI Knock Outs for MAGI1:

miRNA for MAGI1 Gene

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MAGI1

Clone products for research

  • Addgene plasmids for MAGI1

No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for MAGI1 Gene

Localization for MAGI1 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MAGI1 Gene

Cell junction, tight junction. Cell membrane. Peripheral membrane protein. Note=Localizes to epithelial cells tight junctions.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MAGI1 gene
Compartment Confidence
nucleus 5
plasma membrane 4
extracellular 1
cytoskeleton 1
mitochondrion 1
endosome 1
cytosol 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cell Junctions (3)
  • Nucleoplasm (2)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for MAGI1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus IEA --
GO:0005654 nucleoplasm IDA --
GO:0005730 nucleolus IDA --
GO:0005737 cytoplasm IBA,IDA 16464232
GO:0005886 plasma membrane TAS,IDA 20298433
genes like me logo Genes that share ontologies with MAGI1: view

Pathways & Interactions for MAGI1 Gene

PathCards logo

SuperPathways for MAGI1 Gene

genes like me logo Genes that share pathways with MAGI1: view

Pathways by source for MAGI1 Gene

4 GeneGo (Thomson Reuters) pathways for MAGI1 Gene
  • Cell adhesion_Endothelial cell contacts by junctional mechanisms
  • Cell adhesion_Endothelial cell contacts by non-junctional mechanisms
  • G-protein signaling_H-RAS regulation pathway
  • G-protein signaling_Rap1A regulation pathway
1 Qiagen pathway for MAGI1 Gene
  • Epithelial Tight Junctions

Gene Ontology (GO) - Biological Process for MAGI1 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007155 cell adhesion TAS 9647739
GO:0007165 signal transduction IBA 21873635
GO:0007166 cell surface receptor signaling pathway TAS 9647739
GO:0022409 positive regulation of cell-cell adhesion IDA 20298433
GO:0065003 protein-containing complex assembly NAS 9647739
genes like me logo Genes that share ontologies with MAGI1: view

No data available for SIGNOR curated interactions for MAGI1 Gene

Drugs & Compounds for MAGI1 Gene

(1) Additional Compounds for MAGI1 Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with MAGI1: view

Transcripts for MAGI1 Gene

mRNA/cDNA for MAGI1 Gene

6 REFSEQ mRNAs :
17 NCBI additional mRNA sequence :
18 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MAGI1

Clone products for research

  • Addgene plasmids for MAGI1

Alternative Splicing Database (ASD) splice patterns (SP) for MAGI1 Gene

ExUns: 1 ^ 2 ^ 3 ^ 4 ^ 5 ^ 6 ^ 7a · 7b ^ 8a · 8b ^ 9 ^ 10 ^ 11 ^ 12 ^ 13 ^ 14
SP1: - - - -
SP2:
SP3:
SP4:
SP5:

Relevant External Links for MAGI1 Gene

GeneLoc Exon Structure for
MAGI1

Expression for MAGI1 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MAGI1 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

Protein differential expression in normal tissues from HIPED for MAGI1 Gene

This gene is overexpressed in Pancreas (10.1), Fetal Brain (7.6), Amniocyte (6.9), and Plasma (6.2).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MAGI1 Gene



Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MAGI1

SOURCE GeneReport for Unigene cluster for MAGI1 Gene:

Hs.476636

mRNA Expression by UniProt/SwissProt for MAGI1 Gene:

Q96QZ7-MAGI1_HUMAN
Tissue specificity: Widely expressed with the exception of skeletal muscle. Isoform 1, isoform 2 and isoform 6 are highly expressed in colon, kidney, lung, liver, and pancreas. Isoform 5 is predominantly expressed in brain and heart. Isoform 3 and isoform 4 are highly expressed in pancreas and brain.

Evidence on tissue expression from TISSUES for MAGI1 Gene

  • Nervous system(4.8)
  • Liver(4.4)
  • Kidney(3.6)
  • Intestine(3)
  • Lung(2.6)
  • Eye(2.4)
genes like me logo Genes that share expression patterns with MAGI1: view

Primer products for research

No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners and Phenotype-based relationships between genes and organs from Gene ORGANizer for MAGI1 Gene

Orthologs for MAGI1 Gene

This gene was present in the common ancestor of animals.

Orthologs for MAGI1 Gene

Organism Taxonomy Gene Similarity Type Details
Chimpanzee
(Pan troglodytes)
Mammalia MAGI1 29 30
  • 99.7 (n)
OneToOne
Dog
(Canis familiaris)
Mammalia -- 30
  • 97 (a)
OneToMany
MAGI1 29
  • 89.04 (n)
-- 30
  • 80 (a)
OneToMany
Cow
(Bos Taurus)
Mammalia MAGI1 29 30
  • 91.89 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Magi1 29
  • 90.57 (n)
Mouse
(Mus musculus)
Mammalia Magi1 29 16 30
  • 89.44 (n)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia MAGI1 30
  • 87 (a)
OneToOne
Platypus
(Ornithorhynchus anatinus)
Mammalia MAGI1 30
  • 86 (a)
OneToOne
Chicken
(Gallus gallus)
Aves MAGI1 29 30
  • 80.81 (n)
OneToOne
Lizard
(Anolis carolinensis)
Reptilia MAGI1 30
  • 84 (a)
OneToOne
African clawed frog
(Xenopus laevis)
Amphibia Xl.19209 29
Zebrafish
(Danio rerio)
Actinopterygii magi1b 29 30
  • 72.34 (n)
OneToMany
magi1a 30
  • 58 (a)
OneToMany
wufj98f08 29
Fruit Fly
(Drosophila melanogaster)
Insecta Magi 30
  • 30 (a)
OneToMany
Worm
(Caenorhabditis elegans)
Secernentea magi-1 30
  • 33 (a)
OneToMany
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 30
  • 39 (a)
OneToMany
Species where no ortholog for MAGI1 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)

Evolution for MAGI1 Gene

ENSEMBL:
Gene Tree for MAGI1 (if available)
TreeFam:
Gene Tree for MAGI1 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for MAGI1: view image
Alliance of Genome Resources:
Additional Orthologs for MAGI1

Paralogs for MAGI1 Gene

Paralogs for MAGI1 Gene

(10) SIMAP similar genes for MAGI1 Gene using alignment to 5 proteins:

  • MAGI1_HUMAN
  • H7C4S7_HUMAN
  • H7C4U7_HUMAN
  • H7C535_HUMAN
  • H7C5T8_HUMAN

Pseudogenes.org Pseudogenes for MAGI1 Gene

genes like me logo Genes that share paralogs with MAGI1: view

Variants for MAGI1 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MAGI1 Gene

SNP ID Clinical significance and condition Chr 03 pos Variation AA Info Type
rs141859891 Likely Benign: not specified 65,442,805(-) T/C
NM_015520.2(MAGI1):c.1123A>G (p.Ile375Val)
MISSENSE
rs142043619 Benign: not provided 65,439,885(-) T/TCTG
NM_015520.2(MAGI1):c.1234_1236CAG[11] (p.Gln421dup)
INFRAME_INSERTION

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MAGI1 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MAGI1 Gene

Variant ID Type Subtype PubMed ID
dgv4769n100 CNV gain 25217958
esv1335536 CNV insertion 17803354
esv2202487 CNV deletion 18987734
esv2302597 CNV deletion 18987734
esv2562385 CNV insertion 19546169
esv2661867 CNV deletion 23128226
esv2663523 CNV deletion 23128226
esv2725361 CNV deletion 23290073
esv2725364 CNV deletion 23290073
esv2725365 CNV deletion 23290073
esv2725366 CNV deletion 23290073
esv2760793 CNV loss 21179565
esv29286 CNV loss 19812545
esv3035021 CNV deletion 24192839
esv3391109 CNV insertion 20981092
esv3562002 CNV deletion 23714750
esv3568825 CNV loss 25503493
esv3575576 CNV gain 25503493
esv3596419 CNV loss 21293372
esv3596421 CNV gain 21293372
esv3596424 CNV loss 21293372
esv3596425 CNV loss 21293372
esv3596426 CNV loss 21293372
esv3596427 CNV gain 21293372
esv3596428 CNV gain 21293372
esv3596429 CNV loss 21293372
esv3596430 CNV loss 21293372
esv3596431 CNV loss 21293372
esv992084 CNV insertion 20482838
nsv1000606 CNV gain 25217958
nsv1000854 CNV loss 25217958
nsv1006381 CNV gain 25217958
nsv1011668 CNV gain 25217958
nsv1012099 CNV gain 25217958
nsv1014307 CNV loss 25217958
nsv1114388 CNV deletion 24896259
nsv1123659 CNV deletion 24896259
nsv1141433 CNV duplication 24896259
nsv1148399 CNV duplication 26484159
nsv1152480 CNV duplication 26484159
nsv3856 CNV insertion 18451855
nsv3857 CNV insertion 18451855
nsv3858 CNV deletion 18451855
nsv460696 CNV loss 19166990
nsv460697 CNV loss 19166990
nsv472140 CNV novel sequence insertion 20440878
nsv473450 CNV novel sequence insertion 20440878
nsv476874 CNV novel sequence insertion 20440878
nsv507099 OTHER sequence alteration 20534489
nsv507100 OTHER sequence alteration 20534489
nsv522932 CNV loss 19592680
nsv526223 CNV loss 19592680
nsv526343 CNV loss 19592680
nsv590546 CNV gain 21841781
nsv590547 CNV loss 21841781
nsv590548 CNV loss 21841781
nsv590549 CNV loss 21841781
nsv954875 CNV duplication 24416366

Variation tolerance for MAGI1 Gene

Residual Variation Intolerance Score: 2.73% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 4.89; 67.56% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for MAGI1 Gene

Human Gene Mutation Database (HGMD)
MAGI1
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MAGI1
Leiden Open Variation Database (LOVD)
MAGI1

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MAGI1 Gene

Disorders for MAGI1 Gene

MalaCards: The human disease database

(2) MalaCards diseases for MAGI1 Gene - From: COP and GCD

Disorder Aliases PubMed IDs
cervical large cell neuroendocrine carcinoma
microscopic colitis
  • colitis, microscopic
- elite association - COSMIC cancer census association via MalaCards
Search MAGI1 in MalaCards View complete list of genes associated with diseases

Additional Disease Information for MAGI1

Human Genome Epidemiology Navigator
(HuGE)
Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with MAGI1: view

No data available for UniProtKB/Swiss-Prot and Genatlas for MAGI1 Gene

Publications for MAGI1 Gene

  1. Cloning and characterization of BAI-associated protein 1: a PDZ domain-containing protein that interacts with BAI1. (PMID: 9647739) Shiratsuchi T … Tokino T (Biochemical and biophysical research communications 1998) 2 3 4 22
  2. JAM4, a junctional cell adhesion molecule interacting with a tight junction protein, MAGI-1. (PMID: 12773569) Hirabayashi S … Hata Y (Molecular and cellular biology 2003) 3 4 22
  3. MAGI-1: a widely expressed, alternatively spliced tight junction protein. (PMID: 11969287) Laura RP … Lasky LA (Experimental cell research 2002) 3 4 22
  4. Membrane-associated guanylate kinase with inverted orientation (MAGI)-1/brain angiogenesis inhibitor 1-associated protein (BAP1) as a scaffolding molecule for Rap small G protein GDP/GTP exchange protein at tight junctions. (PMID: 11168587) Mino A … Takai Y (Genes to cells : devoted to molecular & cellular mechanisms 2000) 3 4 22
  5. Cellular localization and characterization of cytosolic binding partners for Gla domain-containing proteins PRRG4 and PRRG2. (PMID: 23873930) Yazicioglu MN … High KA (The Journal of biological chemistry 2013) 3 4

Products for MAGI1 Gene

Sources for MAGI1 Gene