Aliases for MAGI1 Gene
External Ids for MAGI1 Gene
Previous HGNC Symbols for MAGI1 Gene
Previous GeneCards Identifiers for MAGI1 Gene
The protein encoded by this gene is a member of the membrane-associated guanylate kinase homologue (MAGUK) family. MAGUK proteins participate in the assembly of multiprotein complexes on the inner surface of the plasma membrane at regions of cell-cell contact. The product of this gene may play a role as scaffolding protein at cell-cell junctions. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
GeneCards Summary for MAGI1 Gene
MAGI1 (Membrane Associated Guanylate Kinase, WW And PDZ Domain Containing 1) is a Protein Coding gene. Diseases associated with MAGI1 include Cervical Large Cell Neuroendocrine Carcinoma and Microscopic Colitis. Among its related pathways are Pathways Affected in Adenoid Cystic Carcinoma and G-protein signaling_H-RAS regulation pathway. Gene Ontology (GO) annotations related to this gene include protein C-terminus binding and alpha-actinin binding. An important paralog of this gene is MAGI2.
UniProtKB/Swiss-Prot Summary for MAGI1 Gene
May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity).