Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsib... See more...

Aliases for MAGEL2 Gene

Aliases for MAGEL2 Gene

  • MAGE Family Member L2 2 3 5
  • Melanoma Antigen Family L2 2 3
  • Necdin-Like Protein 1 3 4
  • MAGE-Like Protein 2 3 4
  • Protein NM15 3 4
  • NDNL1 3 4
  • NM15 2 3
  • MAGE-Like 2 2
  • SHFYNG 3
  • MAGEL2 5
  • PWLS 3

External Ids for MAGEL2 Gene

Previous HGNC Symbols for MAGEL2 Gene

  • NDNL1

Previous GeneCards Identifiers for MAGEL2 Gene

  • GC15M021024
  • GC15M016778
  • GC15M021306
  • GC15M021436
  • GC15M021439
  • GC15M023888
  • GC15M002024

Summaries for MAGEL2 Gene

Entrez Gene Summary for MAGEL2 Gene

  • Prader-Willi syndrome (PWS) is caused by the loss of expression of imprinted genes in chromosome 15q11-q13 region. Affected individuals exhibit neonatal hypotonia, developmental delay, and childhood-onset obesity. Necdin (NDN), a gene involved in the terminal differentiation of neurons, localizes to this region of the genome and has been implicated as one of the genes responsible for the etiology of PWS. This gene is structurally similar to NDN, is also localized to the PWS chromosomal region, and is paternally imprinted, suggesting a possible role for it in PWS. [provided by RefSeq, Oct 2010]

GeneCards Summary for MAGEL2 Gene

MAGEL2 (MAGE Family Member L2) is a Protein Coding gene. Diseases associated with MAGEL2 include Schaaf-Yang Syndrome and Prader-Willi Syndrome. Among its related pathways are Circadian rythm related genes. Gene Ontology (GO) annotations related to this gene include ubiquitin-protein transferase activity. An important paralog of this gene is MAGED1.

UniProtKB/Swiss-Prot Summary for MAGEL2 Gene

  • Probably enhances ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases, possibly through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Acts as a regulator of retrograde transport via its interaction with VPS35. Recruited to retromer-containing endosomes and promotes the formation of 'Lys-63'-linked polyubiquitin chains at 'Lys-220' of WASHC1 together with TRIM27, leading to promote endosomal F-actin assembly (PubMed:23452853). Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Significantly promotes the cytoplasmic accumulation of CLOCK (By similarity).

No data available for CIViC Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for MAGEL2 Gene

Genomics for MAGEL2 Gene

GeneHancer (GH) Regulatory Elements Pubs

Promoters and enhancers for MAGEL2 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH15J023647 Promoter/Enhancer 1.1 Ensembl ENCODE CraniofacialAtlas 250.7 +0.2 166 2.2 TAF1 CTCF CHD1 EGR1 SP1 POLR2A HSALNG0104510 MAGEL2 MKRN3
GH15J023685 Promoter/Enhancer 1.1 Ensembl ENCODE CraniofacialAtlas 11.7 -38.9 -38934 2.1 TAF1 NRF1 L3MBTL2 ZFX POLR2A NDN MAGEL2 HSALNG0104511 lnc-NDN-5 lnc-MKRN3-5
GH15J023689 Enhancer 1.1 Ensembl ENCODE CraniofacialAtlas 10.8 -42.9 -42877 2.8 CEBPA HOMEZ THAP11 FOXA2 KDM6A SMAD4 SAP130 ETV4 RARA GABPB1 MAGEL2 MKRN3 NDN HSALNG0104511 lnc-NDN-5 lnc-MKRN3-5 NPAP1
GH15J023870 Promoter 0.8 CraniofacialAtlas 10.4 -221.5 -221487 0.2 HOMEZ SMAD4 SAP130 GABPB1 NRF1 TAF1 RFX1 SP5 USF2 KAT8 MAGEL2 HSALNG0104521 HSALNG0104516 NDN NPAP1
GH15J023869 Enhancer 0.6 ENCODE 10.4 -221.7 -221732 0.1 NFIC TBP HOMEZ SMAD4 SAP130 GABPB1 ZFP91 NRF1 TAF1 RFX1 MAGEL2 HSALNG0104521 HSALNG0104516 NDN NPAP1
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around MAGEL2 on the GeneHancer Hub at the UCSC Golden Path

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for MAGEL2

Top Transcription factor binding sites by QIAGEN in the MAGEL2 gene promoter:
  • AML1a
  • AP-1
  • CREB
  • E47
  • GR
  • GR-alpha
  • Hand1
  • HOXA5
  • MyoD

Genomic Locations for MAGEL2 Gene

Latest Assembly
chr15:23,643,549-23,647,867
(GRCh38/hg38)
Size:
4,319 bases
Orientation:
Minus strand

Previous Assembly
chr15:23,888,696-23,893,014
(GRCh37/hg19 by Entrez Gene)
Size:
4,319 bases
Orientation:
Minus strand

chr15:23,888,691-23,891,175
(GRCh37/hg19 by Ensembl)
Size:
2,485 bases
Orientation:
Minus strand

Alternative Locations (GRCh38/hg38)

  • chr15(PATCHES):4,591,013-4,595,331 (-)

Genomic View for MAGEL2 Gene

Genes around MAGEL2 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
MAGEL2 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for MAGEL2 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for MAGEL2 Gene

Proteins for MAGEL2 Gene

  • Protein details for MAGEL2 Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q9UJ55-MAGL2_HUMAN
    Recommended name:
    MAGE-like protein 2
    Protein Accession:
    Q9UJ55
    Secondary Accessions:
    • H0YDD5

    Protein attributes for MAGEL2 Gene

    Size:
    1249 amino acids
    Molecular mass:
    132822 Da
    Quaternary structure:
    • Interacts with TRIM27. Interacts with VPS35; leading to recruitment at retromer-containing endosomes. Interacts with ARNTL/BMAL1 and PER2 (By similarity).
    SequenceCaution:
    • Sequence=AAG28577.1; Type=Frameshift; Evidence={ECO:0000305}; Sequence=CAB62393.1; Type=Frameshift; Evidence={ECO:0000305};
    Miscellaneous:
    • Imprinted, expressed from the paternal chromosome only.

neXtProt entry for MAGEL2 Gene

Post-translational modifications for MAGEL2 Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

Other Protein References for MAGEL2 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for MAGEL2 Gene

Domains & Families for MAGEL2 Gene

Gene Families for MAGEL2 Gene

HGNC:
Human Protein Atlas (HPA):
  • Disease related genes
  • Predicted intracellular proteins

Protein Domains for MAGEL2 Gene

InterPro:
Blocks:
  • MAGE protein

Suggested Antigen Peptide Sequences for MAGEL2 Gene

GenScript: Design optimal peptide antigens:
  • Protein nM15 (MAGL2_HUMAN)
  • MAGEL2 protein (Q05BN9_HUMAN)
  • MAGEL2 protein (Q2M1Q7_HUMAN)
  • MAGEL2 protein (Q6P3U4_HUMAN)
genes like me logo Genes that share domains with MAGEL2: view

No data available for Graphical View of Domain Structure and UniProtKB/Swiss-Prot for MAGEL2 Gene

Function for MAGEL2 Gene

Molecular function for MAGEL2 Gene

UniProtKB/Swiss-Prot Function:
Probably enhances ubiquitin ligase activity of RING-type zinc finger-containing E3 ubiquitin-protein ligases, possibly through recruitment and/or stabilization of the Ubl-conjugating enzyme (E2) at the E3:substrate complex. Acts as a regulator of retrograde transport via its interaction with VPS35. Recruited to retromer-containing endosomes and promotes the formation of 'Lys-63'-linked polyubiquitin chains at 'Lys-220' of WASHC1 together with TRIM27, leading to promote endosomal F-actin assembly (PubMed:23452853). Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Significantly promotes the cytoplasmic accumulation of CLOCK (By similarity).
GENATLAS Biochemistry:
melanoma antigen (MAGE)-like 2,intronless located in the PWCR region,(paternally) expressed in brain,fetal and adult,maternally imprinted

Phenotypes From GWAS Catalog for MAGEL2 Gene

Gene Ontology (GO) - Molecular Function for MAGEL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0004842 ubiquitin-protein transferase activity IMP 23452853
GO:0005515 protein binding IPI 23452853
genes like me logo Genes that share ontologies with MAGEL2: view
genes like me logo Genes that share phenotypes with MAGEL2: view

Human Phenotype Ontology for MAGEL2 Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for MAGEL2 Gene

MGI Knock Outs for MAGEL2:

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MAGEL2

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for MAGEL2 Gene

Localization for MAGEL2 Gene

Subcellular locations from UniProtKB/Swiss-Prot for MAGEL2 Gene

Early endosome. Cytoplasm. Nucleus. Note=Recruited to retromer-containing endosomes via interaction with VPS35. Colocalizes with CLOCK and ARNTL/BMLA1 in the cytoplasm, and with PER2 in the cytoplasm and nucleus (By similarity). {ECO:0000250 UniProtKB:Q9QZ04, ECO:0000269 PubMed:23452853}.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for MAGEL2 gene
Compartment Confidence
endosome 5
nucleus 4
cytosol 2
plasma membrane 1
extracellular 1
cytoskeleton 1
mitochondrion 1
peroxisome 1
endoplasmic reticulum 1
lysosome 1
golgi apparatus 1

Gene Ontology (GO) - Cellular Components for MAGEL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005634 nucleus ISS --
GO:0005737 cytoplasm IEA --
GO:0005768 endosome IEA,IDA 23452853
GO:0005769 early endosome IEA --
GO:0005829 cytosol IEA --
genes like me logo Genes that share ontologies with MAGEL2: view

No data available for Subcellular locations from the Human Protein Atlas (HPA) for MAGEL2 Gene

Pathways & Interactions for MAGEL2 Gene

PathCards logo

SuperPathways for MAGEL2 Gene

SuperPathway Contained pathways
1 Circadian rythm related genes
genes like me logo Genes that share pathways with MAGEL2: view

Pathways by source for MAGEL2 Gene

1 BioSystems pathway for MAGEL2 Gene

Interacting Proteins for MAGEL2 Gene

SIGNOR curated interactions for MAGEL2 Gene

Activates:
Is inactivated by:

Gene Ontology (GO) - Biological Process for MAGEL2 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0034314 Arp2/3 complex-mediated actin nucleation IDA 23452853
GO:0042147 retrograde transport, endosome to Golgi IDA 23452853
GO:0042752 regulation of circadian rhythm IEA,ISS --
GO:0045892 negative regulation of transcription, DNA-templated IEA,ISS --
GO:0048511 rhythmic process IEA --
genes like me logo Genes that share ontologies with MAGEL2: view

Drugs & Compounds for MAGEL2 Gene

No Compound Related Data Available

Transcripts for MAGEL2 Gene

mRNA/cDNA for MAGEL2 Gene

1 REFSEQ mRNAs :
5 NCBI additional mRNA sequence :
1 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Inhibitory RNAs for research

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for MAGEL2

Alternative Splicing Database (ASD) splice patterns (SP) for MAGEL2 Gene

No ASD Table

Relevant External Links for MAGEL2 Gene

GeneLoc Exon Structure for
MAGEL2

Expression for MAGEL2 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for MAGEL2 Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for MAGEL2 Gene

This gene is overexpressed in Brain - Hypothalamus (x12.3), Pituitary (x7.4), and Brain - Nucleus accumbens (basal ganglia) (x4.9).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for MAGEL2 Gene



Transcriptomic regulation report from SPP (The Signaling Pathways Project) for MAGEL2

SOURCE GeneReport for Unigene cluster for MAGEL2 Gene:

Hs.141496

mRNA Expression by UniProt/SwissProt for MAGEL2 Gene:

Q9UJ55-MAGL2_HUMAN
Tissue specificity: Expressed in placenta, fetal and adult brain. Not detected in heart and small intestine, very low levels in fibroblasts. Not expressed in brain of a Prader-Willi patient.

Evidence on tissue expression from TISSUES for MAGEL2 Gene

  • Nervous system(4.4)

Phenotype-based relationships between genes and organs from Gene ORGANizer for MAGEL2 Gene

Germ Layers:
  • ectoderm
  • endoderm
  • mesoderm
Systems:
  • cardiovascular
  • digestive
  • endocrine
  • integumentary
  • nervous
  • reproductive
  • respiratory
  • skeletal muscle
  • skeleton
Regions:
Head and neck:
  • brain
  • cranial nerve
  • ear
  • eye
  • face
  • forehead
  • head
  • jaw
  • lip
  • mandible
  • maxilla
  • mouth
  • pharynx
  • pituitary gland
  • skull
Thorax:
  • breast
  • heart
Abdomen:
  • intestine
  • large intestine
Pelvis:
  • ovary
  • penis
  • prostate
  • rectum
  • testicle
  • uterus
  • vagina
  • vulva
Limb:
  • ankle
  • digit
  • elbow
  • finger
  • foot
  • hand
  • hip
  • knee
  • lower limb
  • shoulder
  • toe
  • upper limb
  • wrist
General:
  • blood vessel
  • hair
  • peripheral nerve
  • peripheral nervous system
  • skin
  • spinal cord
genes like me logo Genes that share expression patterns with MAGEL2: view

Primer products for research

No data available for Protein differential expression in normal tissues and Protein tissue co-expression partners for MAGEL2 Gene

Orthologs for MAGEL2 Gene

This gene was present in the common ancestor of chordates.

Orthologs for MAGEL2 Gene

Organism Taxonomy Gene Similarity Type Details
Dog
(Canis familiaris)
Mammalia LOC100684492 29
  • 85.69 (n)
MAGEL2 30
  • 44 (a)
OneToOne
Cow
(Bos Taurus)
Mammalia MAGEL2 29 30
  • 80.83 (n)
OneToOne
Rat
(Rattus norvegicus)
Mammalia Magel2 29
  • 76.15 (n)
Mouse
(Mus musculus)
Mammalia Magel2 29 16 30
  • 73.89 (n)
OneToOne
Oppossum
(Monodelphis domestica)
Mammalia -- 30
  • 45 (a)
ManyToMany
-- 30
  • 33 (a)
ManyToMany
Platypus
(Ornithorhynchus anatinus)
Mammalia -- 30
  • 41 (a)
OneToMany
Chicken
(Gallus gallus)
Aves MAGE 30
  • 43 (a)
OneToMany
Lizard
(Anolis carolinensis)
Reptilia -- 30
  • 39 (a)
OneToMany
Zebrafish
(Danio rerio)
Actinopterygii ndnl2 30
  • 39 (a)
OneToMany
Sea Squirt
(Ciona savignyi)
Ascidiacea -- 30
  • 36 (a)
OneToMany
Species where no ortholog for MAGEL2 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Eremothecium gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • Alpha proteobacteria (Wolbachia pipientis)
  • Amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • Baker's yeast (Saccharomyces cerevisiae)
  • Barley (Hordeum vulgare)
  • Beta proteobacteria (Neisseria meningitidis)
  • Bread mold (Neurospora crassa)
  • Chimpanzee (Pan troglodytes)
  • Chromalveolata (Phytophthora infestans)
  • Common water flea (Daphnia pulex)
  • Corn (Zea mays)
  • E. coli (Escherichia coli)
  • Filamentous fungi (Aspergillus nidulans)
  • Firmicute Bacteria (Streptococcus pneumoniae)
  • Fission Yeast (Schizosaccharomyces pombe)
  • Fruit Fly (Drosophila melanogaster)
  • Green Algae (Chlamydomonas reinhardtii)
  • Honey Bee (Apis mellifera)
  • K. Lactis Yeast (Kluyveromyces lactis)
  • Loblloly Pine (Pinus taeda)
  • Malaria Parasite (Plasmodium falciparum)
  • Medicago Trunc (Medicago Truncatula)
  • Moss (Physcomitrella patens)
  • Orangutan (Pongo pygmaeus)
  • Pig (Sus scrofa)
  • Rainbow Trout (Oncorhynchus mykiss)
  • Rice (Oryza sativa)
  • Rice Blast Fungus (Magnaporthe grisea)
  • Schistosome Parasite (Schistosoma mansoni)
  • Sea Anemone (Nematostella vectensis)
  • Sea Vase (Ciona intestinalis)
  • Sea Urchin (Strongylocentrotus purpuratus)
  • Sorghum (Sorghum bicolor)
  • Soybean (Glycine max)
  • Stem Rust Fungus (Puccinia graminis)
  • Sugarcane (Saccharum officinarum)
  • Thale Cress (Arabidopsis thaliana)
  • Tomato (Lycopersicon esculentum)
  • Toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • Tropical Clawed Frog (Silurana tropicalis)
  • Wheat (Triticum aestivum)
  • Worm (Caenorhabditis elegans)

Evolution for MAGEL2 Gene

ENSEMBL:
Gene Tree for MAGEL2 (if available)
TreeFam:
Gene Tree for MAGEL2 (if available)
Aminode:
Evolutionary constrained regions (ECRs) for MAGEL2: view image
Alliance of Genome Resources:
Additional Orthologs for MAGEL2

Paralogs for MAGEL2 Gene

(30) SIMAP similar genes for MAGEL2 Gene using alignment to 5 proteins:

  • MAGL2_HUMAN
  • H0YDD5_HUMAN
  • Q05BN9_HUMAN
  • Q2M1Q7_HUMAN
  • Q6P3U4_HUMAN
genes like me logo Genes that share paralogs with MAGEL2: view

Variants for MAGEL2 Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for MAGEL2 Gene

SNP ID Clinical significance and condition Chr 15 pos Variation AA Info Type
1005655 Uncertain Significance: not provided 23,646,806(-) C/A
NM_019066.5(MAGEL2):c.937G>T (p.Ala313Ser)
MISSENSE
1008609 Uncertain Significance: not provided 23,645,897(-) C/T
NM_019066.5(MAGEL2):c.1846G>A (p.Ala616Thr)
MISSENSE
1010641 Uncertain Significance: not provided 23,646,704(-) C/G
NM_019066.5(MAGEL2):c.1039G>C (p.Ala347Pro)
MISSENSE
1028137 Uncertain Significance: Schaaf-Yang syndrome 23,646,595(-) T/TGCC
NM_019066.5(MAGEL2):c.1145_1147dup (p.Gln383_Ala384insArg)
INFRAME_INSERTION
1028138 Uncertain Significance: Schaaf-Yang syndrome 23,646,555(-) C/T
NM_019066.5(MAGEL2):c.1188G>A (p.Trp396Ter)
NONSENSE

dbSNP identifiers (rs#s) for variants without ClinVar clinical significance for MAGEL2 Gene

All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).

Structural Variations from Database of Genomic Variants (DGV) for MAGEL2 Gene

Variant ID Type Subtype PubMed ID
esv3892632 CNV gain 25118596
nsv1038443 CNV gain 25217958
nsv1042668 CNV loss 25217958
nsv568341 CNV gain 21841781

Variation tolerance for MAGEL2 Gene

Gene Damage Index Score: 5.13; 69.29% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for MAGEL2 Gene

Human Gene Mutation Database (HGMD)
MAGEL2
SNPedia medical, phenotypic, and genealogical associations of SNPs for
MAGEL2
Leiden Open Variation Database (LOVD)
MAGEL2

SNP Genotyping and Copy Number Assays for research

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for MAGEL2 Gene

Disorders for MAGEL2 Gene

MalaCards: The human disease database

(20) MalaCards diseases for MAGEL2 Gene - From: OMI, CVR, GTR, ORP, COP, and GCD

UniProtKB/Swiss-Prot

MAGL2_HUMAN
  • Schaaf-Yang syndrome (SHFYNG) [MIM:615547]: A disease characterized by clinical features of Prader-Willi syndrome, including neonatal hypotonia with poor suck, feeding problems in infancy, obesity, developmental delay, short stature, and hypogonadism. Additionally, patients manifest autism spectrum disorder. Some patients have dysmorphic facial features. {ECO:0000269 PubMed:24076603}. Note=The disease is caused by variants affecting the gene represented in this entry. All mutations occurred on the paternal allele.

Additional Disease Information for MAGEL2

Human Genome Epidemiology Navigator
(HuGE)
Atlas
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
Open Targets Platform
Open Targets Platform
genes like me logo Genes that share disorders with MAGEL2: view

No data available for Genatlas for MAGEL2 Gene

Publications for MAGEL2 Gene

  1. Truncating mutations of MAGEL2 cause Prader-Willi phenotypes and autism. (PMID: 24076603) Schaaf CP … Yang Y (Nature genetics 2013) 3 4 72
  2. The human MAGEL2 gene and its mouse homologue are paternally expressed and mapped to the Prader-Willi region. (PMID: 10556298) Boccaccio I … Muscatelli F (Human molecular genetics 1999) 2 3 4
  3. Regulation of WASH-dependent actin polymerization and protein trafficking by ubiquitination. (PMID: 23452853) Hao YH … Potts PR (Cell 2013) 3 4
  4. Lack of association between MAGEL2 and schizophrenia and mood disorders in the Japanese population. (PMID: 20467835) Fukuo Y … Iwata N (Neuromolecular medicine 2010) 3 40
  5. MAGE-RING protein complexes comprise a family of E3 ubiquitin ligases. (PMID: 20864041) Doyle JM … Potts PR (Molecular cell 2010) 3 4

Products for MAGEL2 Gene

Sources for MAGEL2 Gene