Aliases for LYRM4 Gene
External Ids for LYRM4 Gene
Previous HGNC Symbols for LYRM4 Gene
Previous GeneCards Identifiers for LYRM4 Gene
The protein encoded by this gene is found in both mitochondria and the nucleus, where it binds cysteine desulfurase and helps free inorganic sulfur for Fe/S clusters. Disruption of this gene negatively impacts mitochondrial and cytosolic iron homeostasis. [provided by RefSeq, Sep 2016]
GeneCards Summary for LYRM4 Gene
LYRM4 (LYR Motif Containing 4) is a Protein Coding gene. Diseases associated with LYRM4 include Combined Oxidative Phosphorylation Deficiency 19 and Combined Oxidative Phosphorylation Deficiency. Among its related pathways are Mitochondrial iron-sulfur cluster biogenesis and Metabolism. An important paralog of this gene is HMGA2.
UniProtKB/Swiss-Prot Summary for LYRM4 Gene
Required for nuclear and mitochondrial iron-sulfur protein biosynthesis.