External Ids for LYRM1 Gene
Previous GeneCards Identifiers for LYRM1 Gene
The protein encoded by this gene belongs to the mitochondrial leucine/tyrosine/arginine motif family of proteins. Proteins of this family are short polypeptides that contain a leucine/tyrosine/arginine motif near the N-terminus. This gene is widely expressed with high levels in omental adipose tissue of obese individuals. In adipose tissue, the protein is localized to the nucleus where it promotes preadipocyte proliferation and lowers the rate of apoptosis to regulate adipose tissue homeostasis. Overexpression of this gene in adipocytes causes abnormal mitochondrial morphology and mitochondrial dysfunction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
GeneCards Summary for LYRM1 Gene
LYRM1 (LYR Motif Containing 1) is a Protein Coding gene. Diseases associated with LYRM1 include Central Hypoventilation Syndrome, Congenital.
UniProtKB/Swiss-Prot Summary for LYRM1 Gene
May promote cell proliferation and inhibition of apoptosis of preadipocytes.