Aliases for LYPLA2 Gene
External Ids for LYPLA2 Gene
Previous GeneCards Identifiers for LYPLA2 Gene
Lysophospholipases are enzymes that act on biological membranes to regulate the multifunctional lysophospholipids. There are alternatively spliced transcript variants described for this gene but the full length nature is not known yet. [provided by RefSeq, Jul 2008]
GeneCards Summary for LYPLA2 Gene
LYPLA2 (Lysophospholipase 2) is a Protein Coding gene. Among its related pathways are Developmental Biology and L1CAM interactions. Gene Ontology (GO) annotations related to this gene include hydrolase activity. An important paralog of this gene is LYPLA1.
UniProtKB/Swiss-Prot Summary for LYPLA2 Gene
Hydrolyzes fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins, GAP43, ZDHHC6 or HRAS (PubMed:21152083, PubMed:28826475). Deacylates GAP43 (PubMed:21152083). Mediates depalmitoylation of ZDHHC6 (PubMed:28826475). Has lysophospholipase activity (By similarity).