Aliases for LYPD6B Gene
Aliases for LYPD6B Gene
External Ids for LYPD6B Gene
- HGNC: 27018
- Entrez Gene: 130576
- Ensembl: ENSG00000150556
- UniProtKB: Q8NI32
Previous GeneCards Identifiers for LYPD6B Gene
- GC02P149604
- GC02P149895
- GC02P141793
Summaries for LYPD6B Gene
GeneCards Summary for LYPD6B Gene
LYPD6B (LY6/PLAUR Domain Containing 6B) is a Protein Coding gene. Diseases associated with LYPD6B include Tobacco Addiction. Among its related pathways are Metabolism of proteins and Post-translational modification- synthesis of GPI-anchored proteins. An important paralog of this gene is LYPD6.
UniProtKB/Swiss-Prot for LYPD6B Gene
-
Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro acts on nAChRs in a subtype- and stoichiometry-dependent manner. Modulates specifically alpha-3(3):beta-4(2) nAChRs by enhancing the sensitivity to ACh, decreasing ACh-induced maximal current response and increasing the rate of desensitization to ACh; has no effect on alpha-7 homomeric nAChRs; modulates alpha-3(2):alpha-5:beta-4(2) nAChRs in the context of CHRNA5/alpha-5 variant Asn-398 but not its wild-type sequence.
Additional gene information for LYPD6B Gene
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LYPD6B Gene
Genomics for LYPD6B Gene
GeneHancer (GH) Regulatory Elements for LYPD6B Gene
Promoters and enhancers for LYPD6B Gene
| GeneHancer (GH) Identifier | GH Type | GH Score |
GH Sources | Gene Association Score | Total Score | TSS distance (kb) | Number of Genes Away | Size (kb) | Transcription Factor Binding Sites |
Gene Targets |
|---|---|---|---|---|---|---|---|---|---|---|
| GH02J149038 | Promoter/Enhancer | 1.7 | EPDnew Ensembl ENCODE | 658.5 | +0.8 | 807 | 1.2 | CTCF ZNF768 MXI1 SIN3A ZMYM3 ZNF335 POLR2A ZNF444 EZH2 SMARCE1 | LYPD6B GC02M149069 | |
| GH02J149126 | Promoter | 0.5 | EPDnew | 650.2 | +88.8 | 88792 | 0.1 | GC02M149098 LYPD6B LOC105373678 | ||
| GH02J149039 | Enhancer | 0.4 | ENCODE | 658.6 | 0.0 | -5 | 0.2 | ZNF335 CTCF ZNF10 | LYPD6B LOC101928553 | |
| GH02J149068 | Enhancer | 1.4 | FANTOM5 Ensembl ENCODE dbSUPER | 23 | +31.5 | 31481 | 2.1 | CLOCK NFIB NEUROD1 SIN3A BMI1 FOS RCOR1 CEBPB GATAD2B ELF1 | TXNP5 GC02M149069 LYPD6B KIF5C GC02M149098 | |
| GH02J149018 | Enhancer | 1.3 | Ensembl ENCODE dbSUPER | 9 | -17.0 | -17041 | 4.3 | FOXA2 SMAD1 NEUROD1 IRF4 ATF7 FOS RUNX3 MCM3 KAT8 SREBF1 | LYPD6 LYPD6B LOC101928553 KIF5C |
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around LYPD6B on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the LYPD6B gene promoter:
-
- AREB6
- HOXA3
- FOXD3
- Tal-1beta
- E47
- YY1
- Pax-4a
- CUTL1
- E2F-1
- FOXO3a
Regulatory Element Products
Genomic Locations for LYPD6B Gene
Genomic Locations for LYPD6B Gene
- chr2:149,038,107-149,215,262
- (GRCh38/hg38)
- Size:
- 177,156 bases
- Orientation:
- Plus strand
- chr2:149,894,621-150,071,776
- (GRCh37/hg19)
- Size:
- 177,156 bases
- Orientation:
- Plus strand
Genomic View for LYPD6B Gene
Genes around LYPD6B on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 2q23.2 by Entrez Gene
- 2q23.2 by HGNC
- 2q23.2 by Ensembl
LYPD6B Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for LYPD6B Gene
Proteins for LYPD6B Gene
-
Protein details for LYPD6B Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q8NI32-LPD6B_HUMAN
- Recommended name:
- Ly6/PLAUR domain-containing protein 6B
- Protein Accession:
- Q8NI32
- D3DP90
- Q53TK0
- Q7Z747
- Q8IXK7
Protein attributes for LYPD6B Gene
- Size:
- 183 amino acids
- Molecular mass:
- 20656 Da
- Quaternary structure:
- No Data Available
- SequenceCaution:
-
- Sequence=AAH18203.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAH18203.1; Type=Frameshift; Positions=150; Evidence={ECO:0000305};
Post-translational modifications for LYPD6B Gene
No Post-translational modifications
Other Protein References for LYPD6B Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for LYPD6B
- Invitrogen Antibodies for LYPD6B
- Search GeneTex for Antibodies for LYPD6B
Protein Products
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for LYPD6B
- Origene Custom Protein Services for LYPD6B
- Novus Biologicals proteins for LYPD6B
- Search GeneTex for Proteins for LYPD6B
Assay Products
No data available for DME Specific Peptides for LYPD6B Gene
Domains & Families for LYPD6B Gene
Gene Families for LYPD6B Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted secreted proteins
- Transporters
Protein Domains for LYPD6B Gene
- Blocks:
- ProtoNet:
Suggested Antigen Peptide Sequences for LYPD6B Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
No data available for UniProtKB/Swiss-Prot for LYPD6B Gene
Function for LYPD6B Gene
Molecular function for LYPD6B Gene
- UniProtKB/Swiss-Prot Function:
- Believed to act as a modulator of nicotinic acetylcholine receptors (nAChRs) activity. In vitro acts on nAChRs in a subtype- and stoichiometry-dependent manner. Modulates specifically alpha-3(3):beta-4(2) nAChRs by enhancing the sensitivity to ACh, decreasing ACh-induced maximal current response and increasing the rate of desensitization to ACh; has no effect on alpha-7 homomeric nAChRs; modulates alpha-3(2):alpha-5:beta-4(2) nAChRs in the context of CHRNA5/alpha-5 variant Asn-398 but not its wild-type sequence.
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0030548 | acetylcholine receptor regulator activity | IDA | 26586467 |
Phenotypes for LYPD6B Gene
- MGI mutant phenotypes for LYPD6B:
- inferred from 1 alleles
- GenomeRNAi human phenotypes for LYPD6B:
Animal Models for LYPD6B Gene
- MGI Knock Outs for LYPD6B:
-
- Lypd6b Lypd6b<tm1b(KOMP)Wtsi>
Animal Model Products
-
Taconic Biosciences Mouse Models for LYPD6B
- Cyagen custom Knockout/knockin (KOKI) mouse models for LYPD6B
-
CRISPR Products
-
OriGene CRISPR knockouts for LYPD6B
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- Applied Biological Materials CRISPR for LYPD6B
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for LYPD6B
- GenScript: Design CRISPR guide RNA sequences for LYPD6B
miRNA for LYPD6B Gene
- miRTarBase miRNAs that target LYPD6B
miRNA Products
Inhibitory RNA Products
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- genomics-online: shRNA clones - Search results for available LYPD6B gene related products
Clone Products
- Sino Biological Human cDNA Clone for LYPD6B
- VectorBuilder custom plasmid, inducible vectors for LYPD6B
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for LYPD6B
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for LYPD6B
- genomics-online: cdna clones - Search results for available LYPD6B gene related products
- orf clones - Search results for available LYPD6B gene related products
- Applied Biological Materials Clones for LYPD6B
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for LYPD6B
No data available for Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Human Phenotype Ontology , Transcription Factor Targets and HOMER Transcription for LYPD6B Gene
Localization for LYPD6B Gene
Subcellular locations from UniProtKB/Swiss-Prot for LYPD6B Gene
- Cell membrane; Lipid-anchor, GPI-anchor.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| extracellular | 5 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | TAS | -- |
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0016020 | membrane | IEA | -- |
| GO:0031225 | anchored component of membrane | IEA | -- |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for LYPD6B Gene
Pathways & Interactions for LYPD6B Gene
Pathways by source for LYPD6B Gene
3 Reactome pathways for LYPD6B Gene
Interacting Proteins for LYPD6B Gene
| Symbol | External ID(s) | Details |
|---|---|---|
| CDK5RAP3 |
GPS-Prot Interaction Network for LYPD6B
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006501 | C-terminal protein lipidation | TAS | -- |
| GO:0099601 | regulation of neurotransmitter receptor activity | IEA | -- |
No data available for SIGNOR curated interactions for LYPD6B Gene
Transcripts for LYPD6B Gene
mRNA/cDNA for LYPD6B Gene
- (16) REFSEQ mRNAs :
- (3) Additional mRNA sequences :
- (58) Selected AceView cDNA sequences:
- (11) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000473800 589 bps (uc061onp.1)
- ENST00000409642 1577 bps (uc002twv.2)
- ENST00000409876 1248 bps (uc061onq.1)
- ENST00000409029 1306 bps (uc002twx.2)
- ENST00000480545 545 bps (uc061onr.1)
Unigene Clusters for LYPD6B Gene
- LY6/PLAUR domain containing 6B:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for LYPD6B
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for LYPD6B
- genomics-online: gRNA clones - Search results for available LYPD6B gene related products
- Applied Biological Materials CRISPR for LYPD6B
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for LYPD6B
- GenScript: Design CRISPR guide RNA sequences for LYPD6B
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for LYPD6B
- Browse OriGene Inhibitory RNA Products For LYPD6B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LYPD6B
- genomics-online: shRNA clones - Search results for available LYPD6B gene related products
Clone Products
- Sino Biological Human cDNA Clone for LYPD6B
- VectorBuilder custom plasmid, inducible vectors for LYPD6B
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for LYPD6B
-
VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for LYPD6B
- genomics-online: cdna clones - Search results for available LYPD6B gene related products
- orf clones - Search results for available LYPD6B gene related products
- Applied Biological Materials Clones for LYPD6B
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 | ^ | 4a | · | 4b | · | 4c | ^ | 5 | ^ | 6 | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | ^ | 10 | ^ | 11 | ^ | 12a | · | 12b | ^ | 13 | ^ | 14a | · | 14b | ^ | 15a | · | 15b | ^ | 16a | · | 16b | · | 16c | · |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||||
| SP2: | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||
| SP4: | - | - | - | |||||||||||||||||||||||||||||||||||||||||||||||||
| SP5: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP6: | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | |||||||||||||||||||||||||||||||||||||
| SP7: | - | |||||||||||||||||||||||||||||||||||||||||||||||||||
| SP8: | - | - | - | - | - | - | ||||||||||||||||||||||||||||||||||||||||||||||
| SP9: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP10: | ||||||||||||||||||||||||||||||||||||||||||||||||||||
| SP11: |
| ExUns: | 16d |
|---|---|
| SP1: | |
| SP2: | |
| SP3: | |
| SP4: | |
| SP5: | |
| SP6: | |
| SP7: | |
| SP8: | |
| SP9: | |
| SP10: | |
| SP11: |
Expression for LYPD6B Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Kidney (Urinary System)
- Ureteric Bud Cells Ureteric Bud
- Ureteric Bud Tip Cells Ureteric Bud
-
Eye (Sensory Organs)
- GABAergic Amacrine Cells Inner Nuclear Layer
-
Neurons
- GABAergic Amacrine Cells Inner Nuclear Layer
-
Adipose (Muscoskeletal System)
- Visceral White Adipocytes Visceral White Adipose
- Epiblast (Early Embryonic Tissues)
- NULL (Uncategorized)
-
Gall Bladder (Hepatobiliary System)
-
Ovary (Reproductive System)
mRNA differential expression in normal tissues according to GTEx for LYPD6B Gene
This gene is overexpressed in Skin - Not Sun Exposed (Suprapubic) (x12.2), Skin - Sun Exposed (Lower leg) (x11.6), Stomach (x5.8), and Testis (x4.7).
NURSA nuclear receptor signaling pathways regulating expression of LYPD6B Gene:
LYPD6BSOURCE GeneReport for Unigene cluster for LYPD6B Gene:
Hs.357567Evidence on tissue expression from TISSUES for LYPD6B Gene
- Nervous system(4)
Primer Products
-
OriGene qPCR primer pairs and template standards for LYPD6B
-
OriGene qPCR primer pairs for LYPD6B
- genomics-online: primer clones - Search results for available LYPD6B gene related products
Gene Expression Assay Products
No data available for Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for LYPD6B Gene
Orthologs for LYPD6B Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | LYPD6B 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | LYPD6B 34 |
|
OneToOne | |
| LOC616612 33 |
|
||||
| mouse (Mus musculus) |
Mammalia | Lypd6b 16 34 33 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Lypd6b 33 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | LYPD6B 34 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | LYPD6B 34 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | LYPD6B 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | LYPD6B 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | LYPD6B 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | lypd6b 33 |
|
||
| African clawed frog (Xenopus laevis) |
Amphibia | Xl.2791 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | LOC554606 33 |
|
||
| lypd6b 34 |
|
OneToOne |
- Species where no ortholog for LYPD6B was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for LYPD6B Gene
- ENSEMBL:
- Gene Tree for LYPD6B (if available)
- TreeFam:
- Gene Tree for LYPD6B (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for LYPD6B: view image
Paralogs for LYPD6B Gene
Variants for LYPD6B Gene
| SNP ID | Clin | Chr 02 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000000215 | -- | 149,118,843(+) | T/C | genic_upstream_transcript_variant, intron_variant | |
| rs1000004078 | -- | 149,160,470(+) | G/T | genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000018741 | -- | 149,062,153(+) | A/G | genic_upstream_transcript_variant, intron_variant | |
| rs1000030037 | -- | 149,062,327(+) | T/C | genic_upstream_transcript_variant, intron_variant | |
| rs1000048572 | -- | 149,118,352(+) | A/T | genic_upstream_transcript_variant, intron_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| dgv230n21 | CNV | loss | 19592680 |
| esv2674737 | CNV | deletion | 23128226 |
| esv2751831 | CNV | gain | 17911159 |
| esv33162 | CNV | loss | 17666407 |
| esv3387934 | CNV | insertion | 20981092 |
| esv33982 | CNV | gain | 17666407 |
| esv3592854 | CNV | loss | 21293372 |
| esv3592855 | CNV | loss | 21293372 |
| esv3592856 | CNV | loss | 21293372 |
| esv3592858 | CNV | loss | 21293372 |
| esv3592859 | CNV | loss | 21293372 |
| nsv459718 | CNV | gain | 19166990 |
| nsv515662 | CNV | loss | 19592680 |
| nsv583291 | CNV | gain | 21841781 |
| nsv834407 | CNV | loss | 17160897 |
| nsv834408 | CNV | gain | 17160897 |
Residual Variation Intolerance Score:
66.5% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
2.46;
43.29% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for LYPD6B Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- LYPD6B
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LYPD6B Gene
Disorders for LYPD6B Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| tobacco addiction |
|
|
Search LYPD6B in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for LYPD6B
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No data available for UniProtKB/Swiss-Prot and Genatlas for LYPD6B Gene
Publications for LYPD6B Gene
- The prototoxin LYPD6B modulates heteromeric α3β4-containing nicotinic acetylcholine receptors, but not α7 homomers. (PMID: 26586467) Ochoa V … Whiteaker P (FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2016) 3 4 58
- Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score. (PMID: 20379614) Rose JE … Uhl GR (Molecular medicine (Cambridge, Mass.) 2010) 3 44 58
- Cloning and characterization of a human LYPD7, a new member of the Ly-6 superfamily. (PMID: 18360792) Ni J … Yu L (Molecular biology reports 2009) 2 3 58
- Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. (PMID: 23453885) Cross-Disorder Group of the Psychiatric Genomics Consortium (Lancet (London, England) 2013) 3 58
- A novel LZAP-binding protein, NLBP, inhibits cell invasion. (PMID: 20164180) Kwon J … Kim H (The Journal of biological chemistry 2010) 3 58
Products for LYPD6B Gene
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- GenScript: Design CRISPR guide RNA sequences for LYPD6B
- Design optimal peptide antigens
- CloneReady with Over 120,000 Genes
- Gene Synthesis: Any Gene in Any Vector
- Vector-based siRNA and miRNA, Ready for Transfection
- Gene Mutant Library, Variants up to 10^11
- Plasmid Preparation
- GenScript Custom Peptide Services for LYPD6B
- Sino Biological Human cDNA Clone for LYPD6B
- Browse Sino Biological Recombinant Proteins
- Browse Sino Biological Cell Lysates
- Browse Sino Biological Antibodies
- Browse Sino Biological Assays
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for LYPD6B
- Novus Biologicals proteins for LYPD6B
- Novus Biologicals
- Novus Biologicals Tissue Microarrays
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Taconic Biosciences Mouse Models for LYPD6B
- Find your next knockout model in the Taconic Knockout Repository
- Genetically Engineered Models Available Immediately
- Humanized Mice
- Invitrogen Antibodies for LYPD6B
- Cyagen custom Knockout/knockin (KOKI) mouse models for LYPD6B
- VectorBuilder custom plasmid, inducible vectors for LYPD6B
- VectorBuilder custom lentivirus, adenovirus, AAV vector/virus packaging for LYPD6B
- VectorBuilder Other custom vectors
- Mammalian expression: PiggyBac
- Mammalian Tet-on expression: plasmid
- Mammalian conditional (Cre-Lox): plasmid and PiggyBac
- Mammalian shRNA knockdown: lentiviral, adenoviral, AAV, and PiggyBac
- CRISPR: plasmid gRNA, lentiviral gRNA, and donor plasmid
- Bacterial expression: pET, pBAD, and pCS
- Yeast expression
- antibodies-online: Search results for available LYPD6B related products ranked by validation data
- antibodies-online: Search results for available LYPD6B related products ranked by validation data
- antibodies-online: Search results for available LYPD6B related products ranked by validation data
- Search GeneTex for Antibodies for LYPD6B
- Search GeneTex for Proteins for LYPD6B
- Horizon Cell Lines for LYPD6B
- genomics-online: cdna clones - Search results for available LYPD6B gene related products
- orf clones - Search results for available LYPD6B gene related products
- genomics-online: gRNA clones - Search results for available LYPD6B gene related products
- genomics-online: primer clones - Search results for available LYPD6B gene related products
- genomics-online: shRNA clones - Search results for available LYPD6B gene related products
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for LYPD6B
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for LYPD6B
- GeneCopoeia miRNA 3'UTR Target clone products for LYPD6B
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LYPD6B
Sources for LYPD6B Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt