Aliases for LUZP4 Gene
External Ids for LUZP4 Gene
Previous GeneCards Identifiers for LUZP4 Gene
This gene encodes a leucine-zipper protein that was first defined as a cancer testis antigens. The encoded protein is an RNA binding protein that interacts with the mRNA export receptor nuclear RNA export factor 2. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jan 2016]
GeneCards Summary for LUZP4 Gene
LUZP4 (Leucine Zipper Protein 4) is a Protein Coding gene. Diseases associated with LUZP4 include Parapsoriasis. Among its related pathways are Gene Expression and Transport of Mature Transcript to Cytoplasm.
UniProtKB/Swiss-Prot Summary for LUZP4 Gene
Export adapter involved in mRNA nuclear export in cancer cells. Binds and enhances the RNA-binding activity of the nuclear RNA export factor NXF1. Can restore mRNA export function in cells compromised by loss of mRNA export adapters (PubMed:25662211).