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This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan o... See more...
Aliases for LUM Gene
Aliases for LUM Gene
External Ids for LUM Gene
- HGNC: 6724
- Entrez Gene: 4060
- Ensembl: ENSG00000139329
- OMIM: 600616
- UniProtKB: P51884
Previous HGNC Symbols for LUM Gene
- LDC
Previous GeneCards Identifiers for LUM Gene
- GC12M090819
- GC12M091944
- GC12M091430
- GC12M089999
- GC12M088565
Summaries for LUM Gene
-
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. [provided by RefSeq, Jul 2008]
GeneCards Summary for LUM Gene
LUM (Lumican) is a Protein Coding gene. Diseases associated with LUM include Cornea Plana and Macular Dystrophy, Corneal. Among its related pathways are Degradation of the extracellular matrix and Keratan sulfate/keratin metabolism. Gene Ontology (GO) annotations related to this gene include collagen binding and extracellular matrix structural constituent. An important paralog of this gene is FMOD.
Additional gene information for LUM Gene
- HGNC(6724)
- Entrez Gene(4060)
- Ensembl(ENSG00000139329)
- OMIM(600616)
- UniProtKB(P51884)
- Open Targets Platform(ENSG00000139329)
- Search for LUM at DataMed
- Search for LUM at HumanCyc
No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for LUM Gene
Genomics for LUM Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for LUM Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around LUM on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for LUM
- Top Transcription factor binding sites by QIAGEN in the LUM gene promoter:
-
- AML1a
- CBF-B
- Meis-1
- Meis-1a
- Meis-1b
- NF-Y
- NF-YA
- NF-YB
- PPAR-gamma1
- PPAR-gamma2
Genomic Locations for LUM Gene
Genomic Locations for LUM Gene
- chr12:91,102,629-91,111,494
- (GRCh38/hg38)
- Size:
- 8,866 bases
- Orientation:
- Minus strand
- chr12:91,496,406-91,505,608
- (GRCh37/hg19)
- Size:
- 9,203 bases
- Orientation:
- Minus strand
Genomic View for LUM Gene
Genes around LUM on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12q21.33 by HGNC
- 12q21.33 by Entrez Gene
- 12q21.33 by Ensembl
LUM Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for LUM Gene
Proteins for LUM Gene
-
Protein details for LUM Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P51884-LUM_HUMAN
- Recommended name:
- Lumican
- Protein Accession:
- P51884
- B2R6R5
- Q96QM7
Protein attributes for LUM Gene
- Size:
- 338 amino acids
- Molecular mass:
- 38429 Da
- Quaternary structure:
-
- Binds to laminin.
Protein Expression for LUM Gene
Post-translational modifications for LUM Gene
Other Protein References for LUM Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- LifeSpan BioSciences Lumican Antibody
- G Biosciences Immunotag™ LUM Antibody
- Creative Diagnostics Anti-LUM monoclonal antibody, clone FQS9909(3)
- Novus Biologicals Antibodies for LUM
-
Abcam antibodies for LUM
- Invitrogen Antibodies for LUM (AFLGC-LUM)
- antibodies-online: Show 19 available LUM Antibodies ranked by validation data
- Compare Top LUM Antibodies
-
Recommended
- 62 WB Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 6 IHC Antibodies (anti-human)
- 2 IF/ICC Antibodies (anti-human)
- 2 RIA Antibodies (anti-human)
- 1 FACS Antibody (anti-human)
- 1 IHC (p) Antibody (anti-human)
- 38 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 2 IHC Antibodies (anti-mouse)
- 21 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 2 IHC Antibodies (anti-rat)
-
Santa Cruz Biotechnology (SCBT) Antibodies for LUM
- Sino Biological Antibodies for LUM
Protein Products
- G Biosciences Human Lumican/LUM/LDC, Lyophilized
- Search Origene for MassSpec and Protein Over-expression Lysates for LUM
- Origene Custom Protein Services for LUM
- Sino Biological Recombinant Proteins for LUM
- Sino Biological Cell Lysates for LUM
- ProSpec Recombinant Proteins for LUM
- antibodies-online: Show 21 available LUM Proteins ranked by validation data
- Compare Top LUM Proteins
-
ProSci Proteins for LUM
-
Abcam proteins for LUM
Assay Products
- G Biosciences Immunotag™ Human LUM (Lumican) ELISA and Immunotag™ Lumican ELISA Kit
- RayBiotech Human Lumican ELISA
- antibodies-online: Show 53 available LUM Elisa Kits ranked by validation data
- Compare Top LUM Elisa Kits
-
Quality Products:
- ABIN1115812
- ABIN367235
- ABIN414729
- ABIN1889401
- ABIN1029151
- ABIN5521080
- ABIN2708309
- ABIN4883685
- ABIN2684890
- ABIN5592320
- ABIN1889412
- ABIN843695
- ABIN4993562
- ABIN2708566
- ABIN6719824
- ABIN6205578
- ABIN6205579
- ABIN2684891
- ABIN6730202
- ABIN1141013
- ABIN1889413
- ABIN843696
- ABIN5521081
- ABIN2708668
- ABIN2684892
- ABIN5592321
- ABIN6719780
- ABIN2949194
- ABIN5071049
- ABIN1141014
- ABIN843697
- ABIN1141011
-
Signalway ELISA kits for LUM
-
Abcam assays for LUM
No data available for DME Specific Peptides for LUM Gene
Domains & Families for LUM Gene
Gene Families for LUM Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Plasma proteins
- Predicted secreted proteins
Protein Domains for LUM Gene
- InterPro:
- Blocks:
-
- Cysteine-rich flanking region, N-terminal
- Leucine-rich repeat signature
- ProtoNet:
Suggested Antigen Peptide Sequences for LUM Gene
- GenScript: Design optimal peptide antigens:
-
- Keratan sulfate proteoglycan lumican (LUM_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P51884UniProtKB/Swiss-Prot:
LUM_HUMAN :- Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
- Family:
-
- Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
Function for LUM Gene
Molecular function for LUM Gene
- GENATLAS Biochemistry:
- lumican,keratan sulfate proteoglycan one of the three major constituents of the corneal stroma,playing a role in the regulation of collagen assembly into fibrils in various connective tissues,small-leucine-rich proteoglycans family
Phenotypes From GWAS Catalog for LUM Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005201 | extracellular matrix structural constituent | NAS | 10892350 |
| GO:0005515 | protein binding | IPI | 25304424 |
| GO:0005518 | collagen binding | IBA,IDA | 10892350 |
| GO:0030021 | extracellular matrix structural constituent conferring compression resistance | RCA | 20551380 |
Phenotypes for LUM Gene
- MGI mutant phenotypes for LUM:
-
inferred from 3 alleles
- immune system phenotype
- cardiovascular system phenotype
- cellular phenotype
- behavior/neurological phenotype
- mortality/aging
- muscle phenotype
- homeostasis/metabolism phenotype
- growth/size/body region phenotype
- digestive/alimentary phenotype
- reproductive system phenotype
- vision/eye phenotype
- limbs/digits/tail phenotype
- skeleton phenotype
- hematopoietic system phenotype
- integument phenotype
- GenomeRNAi human phenotypes for LUM:
Animal Models for LUM Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for LUM - Select products 50% OFF >
- * LUM CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for LUM
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for LUM
-
Santa Cruz Biotechnology (SCBT) CRISPR for LUM
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for LUM
- Browse OriGene Inhibitory RNA Products For LUM
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LUM
Clone Products
- Applied Biological Materials (abm): Clones for LUM - Select products 50% OFF >
- * LUM as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for LUM
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for LUM
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for LUM Gene
Localization for LUM Gene
Subcellular locations from UniProtKB/Swiss-Prot for LUM Gene
- Secreted, extracellular space, extracellular matrix.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| lysosome | 4 |
| golgi apparatus | 4 |
| plasma membrane | 2 |
| cytoskeleton | 2 |
| mitochondrion | 2 |
| nucleus | 2 |
| endoplasmic reticulum | 2 |
| cytosol | 2 |
| peroxisome | 1 |
| endosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | HDA,TAS | -- |
| GO:0005583 | fibrillar collagen trimer | IDA | 10734230 |
| GO:0005615 | extracellular space | IBA | 21873635 |
| GO:0005796 | Golgi lumen | TAS | -- |
| GO:0031012 | extracellular matrix | TAS | 7665616 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for LUM Gene
Pathways & Interactions for LUM Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Defective B4GALT1 causes B4GALT1-CDG (CDG-2d) | ||
| 2 | Keratan sulfate/keratin metabolism | ||
| 3 | Glycosaminoglycan metabolism | ||
| 4 | Proteoglycans in cancer | ||
| 5 | HIV Life Cycle |
.45
|
|
Pathways by source for LUM Gene
1 KEGG pathway for LUM Gene
Interacting Proteins for LUM Gene
Selected Interacting proteins:
P51884-LUM_HUMAN
ENSP00000266718
for LUM Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for LUM
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007601 | visual perception | TAS,IEA | -- |
| GO:0014070 | response to organic cyclic compound | IEA | -- |
| GO:0018146 | keratan sulfate biosynthetic process | TAS | -- |
| GO:0030198 | extracellular matrix organization | TAS | -- |
| GO:0030199 | collagen fibril organization | NAS | 10892350 |
No data available for SIGNOR curated interactions for LUM Gene
Drugs & Compounds for LUM Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Copper | Approved, Investigational | Pharma | Target | 249 |
Drug Products
- G Biosciences Human Lumican/LUM/LDC, Lyophilized
Transcripts for LUM Gene
mRNA/cDNA for LUM Gene
- 1 REFSEQ mRNAs :
- 10 NCBI additional mRNA sequence :
- 3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000266718 2671 nts (view in UCSC)
- ENST00000546642 793 nts (view in UCSC)
- ENST00000548071 992 nts (view in UCSC)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for LUM - Select products 50% OFF >
- * LUM CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
-
OriGene CRISPR knockouts for LUM
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for LUM
-
Santa Cruz Biotechnology (SCBT) CRISPR for LUM
miRNA Products
Inhibitory RNA Products
- Origene shrna, sirna, and RNAi products in human, mouse, rat for LUM
- Browse OriGene Inhibitory RNA Products For LUM
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LUM
Clone Products
- Applied Biological Materials (abm): Clones for LUM - Select products 50% OFF >
- * LUM as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * Gene synthesis, site-directed mutagenesis, subcloning, and more services - Browse All
- Sino Biological Human cDNA Clone for LUM
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for LUM
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | · | 3c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||
| SP2: | - | - | |||||||||||||||
| SP3: | - |
Relevant External Links for LUM Gene
- GeneLoc Exon Structure for
- LUM
Expression for LUM Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Tendon & Ligament (Muscoskeletal System)
- Tenocytes Limb Tendons and Ligaments
- Early Tenocyte Cells Axial Tendon Primordia
- Tenocytes Axial Tendons and Ligamnets
- Early Tenocyte Cells Limb Tendon Primordia
mRNA differential expression in normal tissues according to GTEx for LUM Gene
This gene is overexpressed in Lung (x4.4), Heart - Atrial Appendage (x4.1), and Adipose - Visceral (Omentum) (x4.0).
This gene is overexpressed in Breast (6.3) and Synovial fluid (6.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for LUM Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for LUM
SOURCE GeneReport for Unigene cluster for LUM Gene:
Hs.406475mRNA Expression by UniProt/SwissProt for LUM Gene:
P51884-LUM_HUMAN
Tissue specificity:
Cornea and other tissues.
Evidence on tissue expression from TISSUES for LUM Gene
- Lung(4.9)
- Intestine(4.9)
- Eye(4.7)
- Liver(4.6)
- Heart(4.5)
- Bone marrow(4.4)
- Pancreas(4.1)
- Muscle(3.6)
- Stomach(3.6)
- Bone(3.4)
- Gall bladder(3.4)
- Kidney(3.2)
- Nervous system(3.1)
- Lymph node(3.1)
- Skin(3)
- Adrenal gland(3)
- Blood(2.8)
- Spleen(2.4)
- Thyroid gland(2.3)
Primer Products
-
OriGene qPCR primer pairs for LUM
-
OriGene qPCR primer pairs and template standards for LUM
Gene Expression Assay Products
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for LUM Gene
Orthologs for LUM Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | LUM 30 31 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | LUM 30 31 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | LUM 30 31 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Lum 30 17 31 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Lum 30 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | LUM 31 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | LUM 31 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | LUM 30 31 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | LUM 31 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | lum 30 |
|
||
| Str.15551 30 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | MGC64527 30 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | lum 30 31 |
|
OneToOne | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
- Species where no ortholog for LUM was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for LUM Gene
- ENSEMBL:
- Gene Tree for LUM (if available)
- TreeFam:
- Gene Tree for LUM (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for LUM: view image
Paralogs for LUM Gene
Variants for LUM Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for LUM Gene
| SNP ID | Clinical significance and condition | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs147975710 | - | p.Leu199Pro |
Residual Variation Intolerance Score:
35.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.08;
22.07% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for LUM Gene
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LUM Gene
Disorders for LUM Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| cornea plana |
|
|
| macular dystrophy, corneal |
|
|
| corneal dystrophy, posterior amorphous |
|
|
| degenerative myopia |
|
|
| corneal dystrophy |
|
|
Search LUM in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for LUM
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for LUM Gene
Publications for LUM Gene
- Primary structure of human lumican (keratan sulfate proteoglycan) and localization of the gene (LUM) to chromosome 12q21.3-q22. (PMID: 7558030) Chakravarti S … Hassell JR (Genomics 1995) 2 3 4 23
- Association of the lumican gene functional 3'-UTR polymorphism with high myopia. (PMID: 19643966) Lin HJ … Tsai FJ (Investigative ophthalmology & visual science 2010) 3 23 41
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 41
- The association between lumican gene polymorphisms and high myopia. (PMID: 20010793) Lin HJ … Tsai FJ (Eye (London, England) 2010) 3 41
- Association of breast cancer susceptibility variants with risk of pancreatic cancer. (PMID: 19843670) Couch FJ … Petersen GM (Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2009) 3 41
ExternalLinks
Products for LUM Gene
- View all 9 R&D Systems LUM (Lumican) Products
- View all R&D Systems LUM (Lumican) Proteins and Enzymes
- View all 5 R&D Systems LUM (Lumican) Primary Antibodies
- View all R&D Systems LUM (Lumican) ELISAs
- View all R&D Systems LUM (Lumican) Luminex Assays
- View all R&D Systems LUM (Lumican) Proteome Profiler Antibody Arrays
- Learn more about R&D Systems custom LUM antibody, protein, and immunoassay development services
- Custom Antibody Services
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for LUM
- Origene Custom Protein Services for LUM
- Origene shrna, sirna, and RNAi products in human, mouse, rat for LUM
- Browse OriGene Inhibitory RNA Products For LUM
- OriGene qPCR primer pairs for LUM
- OriGene qPCR primer pairs and template standards for LUM
- OriGene CRISPR knockouts for LUM
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For LUM
- Sino Biological Human cDNA Clone for LUM
- Sino Biological Recombinant Proteins for LUM
- Sino Biological Cell Lysates for LUM
- Sino Biological Antibodies for LUM
- Browse Sino Biological Assays
- Browse Recombinant Proteins
- Browse Antibodies
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for LUM
- Novus Biologicals proteins and lysates for LUM
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for LUM
- Abcam proteins for LUM
- Abcam assays for LUM
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- ProSpec Recombinant Proteins for LUM
- ESI BIO PureStem Z11, Meso Progenitor for LUM
- Invitrogen Antibodies for LUM (AFLGC-LUM)
- VectorBuilder Custom and pre-made DNA vectors for LUM (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for LUM (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for LUM (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for LUM CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for LUM
- antibodies-online: Show 19 available LUM Antibodies ranked by validation data
- Compare Top LUM Antibodies
- Recommended
- 62 WB Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 6 IHC Antibodies (anti-human)
- 2 IF/ICC Antibodies (anti-human)
- 2 RIA Antibodies (anti-human)
- 1 FACS Antibody (anti-human)
- 1 IHC (p) Antibody (anti-human)
- 38 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 2 IHC Antibodies (anti-mouse)
- 21 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 2 IHC Antibodies (anti-rat)
- antibodies-online: Show 53 available LUM Elisa Kits ranked by validation data
- Compare Top LUM Elisa Kits
- Quality Products:
- ABIN1115812
- ABIN367235
- ABIN414729
- ABIN1889401
- ABIN1029151
- ABIN5521080
- ABIN2708309
- ABIN4883685
- ABIN2684890
- ABIN5592320
- ABIN1889412
- ABIN843695
- ABIN4993562
- ABIN2708566
- ABIN6719824
- ABIN6205578
- ABIN6205579
- ABIN2684891
- ABIN6730202
- ABIN1141013
- ABIN1889413
- ABIN843696
- ABIN5521081
- ABIN2708668
- ABIN2684892
- ABIN5592321
- ABIN6719780
- ABIN2949194
- ABIN5071049
- ABIN1141014
- ABIN843697
- ABIN1141011
- antibodies-online: Show 21 available LUM Proteins ranked by validation data
- Compare Top LUM Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for LUM
- Search Santa Cruz Biotechnology (SCBT) for LUM siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for LUM
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- ProSci Proteins for LUM
- Horizon Cell Lines for LUM
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for LUM
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for LUM
- Search GeneCopoeia for miRNA 3'UTR Target clone products for LUM
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LUM
Sources for LUM Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
- (16) Blocks
- (17) MGI
- (18) IUBMB
- (19) KEGG
- (20) MINT
- (21) STRING
- (22) IntAct
- (23) Novoseek
- (24) PharmGKB
- (25) DrugBank
- (26) HMDB
- (27) ASD
- (28) SAGE
- (29) SOURCE
- (30) HomoloGene
- (31) PanEnsembl
- (32) euGenes
- (33) SGD
- (34) FlyBase
- (35) WormBase
- (36) Pseudogene
- (37) DGV
- (38) dbSNP
- (39) GenAtlas
- (40) HGMD
- (41) GAD
- (42) BGMUT
- (43) HuGE
- (44) Atlas
- (45) GenBank
- (46) HORDE
- (47) HUGE
- (48) IMGT
- (49) Leiden
- (50) miRBase
- (51) DME
- (52) OriGene
- (53) PubMed
- (54) R&D Systems
- (55) TGDB
- (56) Tocris
- (57) Abcam
- (58) Novus Biologicals
- (59) ProSpec
- (60) Sino Biological
- (61) GenScript
- (62) Qiagen
- (63) OCA
- (64) Proteopedia
- (65) MOPED
- (66) neXtProt
- (67) Reactome
- (68) GeneGo (Thomson Reuters)
- (69) DISEASES
- (70) SIMAP
- (71) GenomeRNAi
- (72) LifeMap
- (73) miRTarBase
- (74) MalaCards
- (75) Invitrogen
- (76) BitterDB
- (77) ESI-BIO
- (78) RefSeq
- (79) BioSystems
- (80) MaxQB
- (81) IUPHAR
- (82) BioGPS
- (83) Illumina
- (84) COMPARTMENTS
- (85) HOMER
- (86) PaxDb
- (87) ApexBio
- (88) Addgene
- (89) antibodies-online
- (90) CYP
- (91) NONCODE
- (92) TreeFam
- (93) PathCards
- (94) GeneReviews
- (95) GeneTex
- (96) Taconic Biosciences
- (97) GTEx
- (98) ProteomicsDB
- (99) SCBT
- (100) DGIdb
- (101) ClinicalTrials
- (102) RVIS
- (103) SIGNOR
- (104) diseasecard
- (105) NIH Rare Diseases
- (106) Orphanet
- (107) UMLS
- (108) GTR
- (109) Disease Ontology
- (110) Genetics Home Reference
- (111) MeSH
- (112) MedlinePlus
- (113) CDC
- (114) NINDS
- (115) NCBI Bookshelf
- (116) ClinVar
- (117) Gene Damage Index
- (118) HPO
- (119) UDN
- (120) VISTA
- (121) FANTOM5
- (122) ENCODE
- (123) ProSci
- (124) Horizon
- (125) The Signaling Pathways Project (SPP)
- (126) IID
- (127) VectorBuilder
- (128) SNPedia
- (129) BRCA Exchange
- (130) CIViC
- (131) ProteoGenix
- (132) dbSUPER
- (133) TISSUES
- (134) Gene ORGANizer
- (135) abm
- (136) Human Protein Atlas
- (137) GWAS Catalog
- (138) Monarch Initiative
- (139) DataMed
- (140) HumanCyc
- (141) UCNEbase
- (142) EPDnew
- (143) Applied Biosystems
- (144) GlyConnect
- (145) Aminode
- (146) GeneCopoeia
- (147) GPS-Prot
- (148) RNACentral
- (149) LncRNADisease
- (150) LOVD
- (151) miR2Disease
- (152) DiseaseEnhancer
- (153) Boster Bio
- (154) Biorbyt
- (155) Biocompare
- (156) Mastermind
- (157) CTD^2 Dashboard
- (158) CraniofacialAtlas
- (159) GeneImprint
- (160) Synthego
- (161) ENA
- (162) GtRNAdb
- (163) LncBase
- (164) LncBook
- (165) LNCipedia
- (166) Modomics
- (167) PDBe
- (168) Rfam
- (169) SILVA
- (170) snOPY
- (171) SRPDB
- (172) GENCODE
- (173) TarBase
- (174) Signalway Antibody
- (175) Open Targets Platform
- (176) 5SRRNADB
- (177) snoDB
- (178) MirGeneDB