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This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan o... See more...
Aliases for LUM Gene
Aliases for LUM Gene
External Ids for LUM Gene
- HGNC: 6724
- NCBI Entrez Gene: 4060
- Ensembl: ENSG00000139329
- OMIM®: 600616
- UniProtKB/Swiss-Prot: P51884
Previous HGNC Symbols for LUM Gene
- LDC
Previous GeneCards Identifiers for LUM Gene
- GC12M090819
- GC12M091944
- GC12M091430
- GC12M089999
- GC12M088565
Summaries for LUM Gene
-
This gene encodes a member of the small leucine-rich proteoglycan (SLRP) family that includes decorin, biglycan, fibromodulin, keratocan, epiphycan, and osteoglycin. In these bifunctional molecules, the protein moiety binds collagen fibrils and the highly charged hydrophilic glycosaminoglycans regulate interfibrillar spacings. Lumican is the major keratan sulfate proteoglycan of the cornea but is also distributed in interstitial collagenous matrices throughout the body. Lumican may regulate collagen fibril organization and circumferential growth, corneal transparency, and epithelial cell migration and tissue repair. [provided by RefSeq, Jul 2008]
GeneCards Summary for LUM Gene
LUM (Lumican) is a Protein Coding gene. Diseases associated with LUM include Cornea Plana and Macular Dystrophy, Corneal. Among its related pathways are Defective ST3GAL3 causes MCT12 and EIEE15 and Proteoglycans in cancer. Gene Ontology (GO) annotations related to this gene include collagen binding and extracellular matrix structural constituent. An important paralog of this gene is FMOD.
Additional gene information for LUM Gene
No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for LUM Gene
Genomics for LUM Gene
GeneHancer (GH) Regulatory Elements Pubs
Promoters and enhancers for LUM Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around LUM on the GeneHancer Hub at the UCSC Golden Path
Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for LUM
- Top Transcription factor binding sites by QIAGEN in the LUM gene promoter:
-
- AML1a
- CBF-B
- Meis-1
- Meis-1a
- Meis-1b
- NF-Y
- NF-YA
- NF-YB
- PPAR-gamma1
- PPAR-gamma2
Genomic Locations for LUM Gene
Latest Assembly
- chr12:91,102,629-91,111,494
- (GRCh38/hg38)
- Size:
- 8,866 bases
- Orientation:
- Minus strand
Previous Assembly
- chr12:91,496,406-91,505,271
- (GRCh37/hg19 by Entrez Gene)
- Size:
- 8,866 bases
- Orientation:
- Minus strand
Genomic View for LUM Gene
Genes around LUM on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 12q21.33 by HGNC
- 12q21.33 by Entrez Gene
- 12q21.33 by Ensembl
LUM Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for LUM Gene
Proteins for LUM Gene
-
Protein details for LUM Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- P51884-LUM_HUMAN
- Recommended name:
- Lumican
- Protein Accession:
- P51884
- B2R6R5
- Q96QM7
Protein attributes for LUM Gene
- Size:
- 338 amino acids
- Molecular mass:
- 38429 Da
- Quaternary structure:
-
- Binds to laminin.
Protein Expression for LUM Gene
Post-translational modifications for LUM Gene
Other Protein References for LUM Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibodies for research
- LifeSpan BioSciences Lumican Antibody
- G Biosciences Immunotag™ LUM Antibody
- Novus Biologicals Antibodies for LUM
-
Abcam antibodies for LUM
- Invitrogen Antibodies for LUM (AFLGC-LUM)
- antibodies-online: Show 19 available LUM Antibodies ranked by validation data
- Compare Top LUM Antibodies
-
Recommended
- 62 WB Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 6 IHC Antibodies (anti-human)
- 2 IF/ICC Antibodies (anti-human)
- 2 RIA Antibodies (anti-human)
- 1 FACS Antibody (anti-human)
- 1 IHC (p) Antibody (anti-human)
- 38 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 2 IHC Antibodies (anti-mouse)
- 21 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 2 IHC Antibodies (anti-rat)
-
Custom Antibody ServicesProSci Antibodies for LUM
-
Santa Cruz Biotechnology (SCBT) Antibodies for LUM
- Sino Biological Antibodies for LUM
Protein products for research
- G Biosciences Human Lumican/LUM/LDC, Lyophilized
- Search Origene for MassSpec and Protein Over-expression Lysates for LUM
- Origene Custom Protein Services for LUM
- Sino Biological Recombinant Proteins for LUM
- Sino Biological Cell Lysates for LUM
- ProSpec Recombinant Proteins for LUM
- antibodies-online: Show 21 available LUM Proteins ranked by validation data
- Compare Top LUM Proteins
-
ProSci Proteins for LUM
-
Abcam proteins for LUM
Assay products for research
- G Biosciences Immunotag™ Human LUM (Lumican) ELISA and Immunotag™ Lumican ELISA Kit
- RayBiotech Human Lumican ELISA
- antibodies-online: Show 53 available LUM Elisa Kits ranked by validation data
- Compare Top LUM Elisa Kits
-
Quality Products:
- ABIN1115812
- ABIN367235
- ABIN414729
- ABIN1889401
- ABIN1029151
- ABIN5521080
- ABIN2708309
- ABIN4883685
- ABIN2684890
- ABIN5592320
- ABIN1889412
- ABIN843695
- ABIN4993562
- ABIN2708566
- ABIN6719824
- ABIN6205578
- ABIN6205579
- ABIN2684891
- ABIN6730202
- ABIN1141013
- ABIN1889413
- ABIN843696
- ABIN5521081
- ABIN2708668
- ABIN2684892
- ABIN5592321
- ABIN6719780
- ABIN2949194
- ABIN5071049
- ABIN1141014
- ABIN843697
- ABIN1141011
-
Abcam assays for LUM
No data available for DME Specific Peptides for LUM Gene
Domains & Families for LUM Gene
Gene Families for LUM Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Cancer-related genes
- Plasma proteins
- Predicted secreted proteins
Protein Domains for LUM Gene
- InterPro:
- Blocks:
-
- Cysteine-rich flanking region, N-terminal
- Leucine-rich repeat signature
Suggested Antigen Peptide Sequences for LUM Gene
- GenScript: Design optimal peptide antigens:
-
- Keratan sulfate proteoglycan lumican (LUM_HUMAN)
Graphical View of Domain Structure for InterPro Entry
P51884UniProtKB/Swiss-Prot:
LUM_HUMAN :- Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
- Family:
-
- Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class II subfamily.
Function for LUM Gene
Molecular function for LUM Gene
- GENATLAS Biochemistry:
- lumican,keratan sulfate proteoglycan one of the three major constituents of the corneal stroma,playing a role in the regulation of collagen assembly into fibrils in various connective tissues,small-leucine-rich proteoglycans family
Phenotypes From GWAS Catalog for LUM Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005201 | extracellular matrix structural constituent | NAS | 10892350 |
| GO:0005515 | protein binding | IPI | 25304424 |
| GO:0005518 | collagen binding | IDA | 10892350 |
| GO:0030021 | extracellular matrix structural constituent conferring compression resistance | RCA | 20551380 |
Phenotypes for LUM Gene
- MGI mutant phenotypes for LUM:
-
inferred from 3 alleles
- muscle phenotype
- homeostasis/metabolism phenotype
- growth/size/body region phenotype
- cellular phenotype
- cardiovascular system phenotype
- behavior/neurological phenotype
- immune system phenotype
- mortality/aging
- hematopoietic system phenotype
- digestive/alimentary phenotype
- reproductive system phenotype
- vision/eye phenotype
- limbs/digits/tail phenotype
- skeleton phenotype
- integument phenotype
- embryo phenotype
- craniofacial phenotype
- GenomeRNAi human phenotypes for LUM:
Animal Models for LUM Gene
Animal Models for research
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for LUM - Starting at $85 >
- * LUM CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for LUM
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for LUM
-
Santa Cruz Biotechnology (SCBT) CRISPR for LUM
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for LUM
- Browse OriGene Inhibitory RNA Products For LUM
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LUM
Clone products for research
- Applied Biological Materials (abm): Clones for LUM - Starting at $45 >
- * LUM as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for LUM
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for LUM
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , miRNA , Transcription Factor Targets and HOMER Transcription for LUM Gene
Localization for LUM Gene
Subcellular locations from UniProtKB/Swiss-Prot for LUM Gene
- Secreted, extracellular space, extracellular matrix.
| Compartment | Confidence |
|---|---|
| extracellular | 5 |
| lysosome | 4 |
| golgi apparatus | 4 |
| plasma membrane | 2 |
| cytoskeleton | 2 |
| mitochondrion | 2 |
| nucleus | 2 |
| endoplasmic reticulum | 2 |
| cytosol | 2 |
| peroxisome | 1 |
| endosome | 1 |
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005576 | extracellular region | HDA,TAS | -- |
| GO:0005583 | fibrillar collagen trimer | IDA | 10734230 |
| GO:0005615 | extracellular space | IBA | 21873635 |
| GO:0005796 | Golgi lumen | TAS | -- |
| GO:0031012 | extracellular matrix | TAS | 7665616 |
No data available for Subcellular locations from the Human Protein Atlas (HPA) for LUM Gene
Pathways & Interactions for LUM Gene
| SuperPathway | Contained pathways | ||
|---|---|---|---|
| 1 | Defective ST3GAL3 causes MCT12 and EIEE15 | ||
| 2 | Keratan sulfate/keratin metabolism | ||
| 3 | Glycosaminoglycan metabolism | ||
| 4 | Proteoglycans in cancer | ||
| 5 | HIV Life Cycle |
.45
|
|
Pathways by source for LUM Gene
1 KEGG pathway for LUM Gene
Interacting Proteins for LUM Gene
Selected Interacting proteins:
P51884-LUM_HUMAN
ENSP00000266718
for LUM Gene via
UniProtKB
STRING
IID
GPS-Prot Interaction Network for LUM
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0007601 | visual perception | TAS,IEA | -- |
| GO:0014070 | response to organic cyclic compound | IEA | -- |
| GO:0018146 | keratan sulfate biosynthetic process | TAS | -- |
| GO:0030198 | extracellular matrix organization | TAS | -- |
| GO:0030199 | collagen fibril organization | NAS | 10892350 |
No data available for SIGNOR curated interactions for LUM Gene
Drugs & Compounds for LUM Gene
| Name | Status | Disease Links | Group | Role | Mechanism of Action | Clinical Trials |
|---|---|---|---|---|---|---|
| Copper | Approved, Investigational | Pharma | Target | 276 |
Drug products for research
- G Biosciences Human Lumican/LUM/LDC, Lyophilized
Transcripts for LUM Gene
mRNA/cDNA for LUM Gene
- 1 REFSEQ mRNAs :
- 10 NCBI additional mRNA sequence :
- 3 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000266718 2671 nts (view in UCSC)
- ENST00000546642 793 nts (view in UCSC)
- ENST00000548071 992 nts (view in UCSC)
CRISPR products for research
- Applied Biological Materials (abm): CRISPR Clones for LUM - Starting at $85 >
- * LUM CRISPR as ready-to-use vector or virus: Non-viral | Lenti- | Adeno- | AAV- | siRNA - Browse All
- * Cas9 Nucleases, Nickases, Null Mutants, and GFP tag also available.
-
OriGene CRISPR knockouts for LUM
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for LUM
-
Santa Cruz Biotechnology (SCBT) CRISPR for LUM
miRNA products for research
Inhibitory RNAs for research
- Origene shrna, sirna, and RNAi products in human, mouse, rat for LUM
- Browse OriGene Inhibitory RNA Products For LUM
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LUM
Clone products for research
- Applied Biological Materials (abm): Clones for LUM - Starting at $45 >
- * LUM as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Retro- | Protein Vector - Browse All
- * Viral Packaging Services and High Titer Production Services also available.
- Sino Biological Human cDNA Clone for LUM
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for LUM
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2a | · | 2b | · | 2c | ^ | 3a | · | 3b | · | 3c |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | |||||||||||||||||
| SP2: | - | - | |||||||||||||||
| SP3: | - |
Relevant External Links for LUM Gene
- GeneLoc Exon Structure for
- LUM
Expression for LUM Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Tendon & Ligament (Muscoskeletal System)
- Tenocytes Limb Tendons and Ligaments
- Early Tenocyte Cells Axial Tendon Primordia
- Tenocytes Axial Tendons and Ligamnets
- Early Tenocyte Cells Limb Tendon Primordia
mRNA differential expression in normal tissues according to GTEx for LUM Gene
This gene is overexpressed in Lung (x4.4), Heart - Atrial Appendage (x4.1), and Adipose - Visceral (Omentum) (x4.0).
This gene is overexpressed in Breast (6.3) and Synovial fluid (6.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB and MOPED for LUM Gene
- Elite partner
Transcriptomic regulation report from SPP (The Signaling Pathways Project) for LUM
SOURCE GeneReport for Unigene cluster for LUM Gene:
Hs.406475mRNA Expression by UniProt/SwissProt for LUM Gene:
P51884-LUM_HUMAN
Tissue specificity:
Cornea and other tissues.
Evidence on tissue expression from TISSUES for LUM Gene
- Lung(4.9)
- Intestine(4.9)
- Eye(4.7)
- Liver(4.5)
- Heart(4.4)
- Bone marrow(4.3)
- Pancreas(4)
- Muscle(3.5)
- Stomach(3.4)
- Bone(3.2)
- Gall bladder(3.1)
- Kidney(3)
- Nervous system(2.8)
- Lymph node(2.8)
- Skin(2.7)
- Adrenal gland(2.5)
- Blood(2.4)
- Thyroid gland(2.1)
Primer products for research
-
OriGene qPCR primer pairs for LUM
-
OriGene qPCR primer pairs and template standards for LUM
Gene Expression Assays for research
No data available for Phenotype-based relationships between genes and organs from Gene ORGANizer for LUM Gene
Orthologs for LUM Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| Chimpanzee (Pan troglodytes) |
Mammalia | LUM 29 30 |
|
OneToOne | |
| Dog (Canis familiaris) |
Mammalia | LUM 29 30 |
|
OneToOne | |
| Cow (Bos Taurus) |
Mammalia | LUM 29 30 |
|
OneToOne | |
| Mouse (Mus musculus) |
Mammalia | Lum 29 16 30 |
|
OneToOne | |
| Rat (Rattus norvegicus) |
Mammalia | Lum 29 |
|
||
| Oppossum (Monodelphis domestica) |
Mammalia | LUM 30 |
|
OneToOne | |
| Platypus (Ornithorhynchus anatinus) |
Mammalia | LUM 30 |
|
OneToOne | |
| Chicken (Gallus gallus) |
Aves | LUM 29 30 |
|
OneToOne | |
| Lizard (Anolis carolinensis) |
Reptilia | LUM 30 |
|
OneToOne | |
| Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | lum 29 |
|
||
| Str.15551 29 |
|
||||
| African clawed frog (Xenopus laevis) |
Amphibia | MGC64527 29 |
|
||
| Zebrafish (Danio rerio) |
Actinopterygii | lum 29 30 |
|
OneToOne | |
| Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 30 |
|
OneToMany |
- Species where no ortholog for LUM was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Eremothecium gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- Alpha proteobacteria (Wolbachia pipientis)
- Amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- Baker's yeast (Saccharomyces cerevisiae)
- Barley (Hordeum vulgare)
- Beta proteobacteria (Neisseria meningitidis)
- Bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- Common water flea (Daphnia pulex)
- Corn (Zea mays)
- E. coli (Escherichia coli)
- Filamentous fungi (Aspergillus nidulans)
- Firmicute Bacteria (Streptococcus pneumoniae)
- Fission Yeast (Schizosaccharomyces pombe)
- Fruit Fly (Drosophila melanogaster)
- Green Algae (Chlamydomonas reinhardtii)
- Honey Bee (Apis mellifera)
- K. Lactis Yeast (Kluyveromyces lactis)
- Loblloly Pine (Pinus taeda)
- Malaria Parasite (Plasmodium falciparum)
- Medicago Trunc (Medicago Truncatula)
- Moss (Physcomitrella patens)
- Orangutan (Pongo pygmaeus)
- Pig (Sus scrofa)
- Rainbow Trout (Oncorhynchus mykiss)
- Rice (Oryza sativa)
- Rice Blast Fungus (Magnaporthe grisea)
- Schistosome Parasite (Schistosoma mansoni)
- Sea Anemone (Nematostella vectensis)
- Sea Vase (Ciona intestinalis)
- Sea Urchin (Strongylocentrotus purpuratus)
- Sorghum (Sorghum bicolor)
- Soybean (Glycine max)
- Stem Rust Fungus (Puccinia graminis)
- Sugarcane (Saccharum officinarum)
- Thale Cress (Arabidopsis thaliana)
- Tomato (Lycopersicon esculentum)
- Toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- Wheat (Triticum aestivum)
- Worm (Caenorhabditis elegans)
Evolution for LUM Gene
- ENSEMBL:
- Gene Tree for LUM (if available)
- TreeFam:
- Gene Tree for LUM (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for LUM: view image
- Alliance of Genome Resources:
- Additional Orthologs for LUM
Paralogs for LUM Gene
Variants for LUM Gene
Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for LUM Gene
| SNP ID | Clinical significance and condition | Chr 12 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs147975710 | -- |
p.Leu199Pro |
All consequence types are included: molecular consequences (e.g. missense, synonymous), and location-based (e.g. intron, upstream).
Residual Variation Intolerance Score:
35.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.08;
22.07% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for LUM Gene
SNP Genotyping and Copy Number Assays for research
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LUM Gene
Disorders for LUM Gene
| Disorder | Aliases | PubMed IDs |
|---|---|---|
| cornea plana |
|
|
| macular dystrophy, corneal |
|
|
| corneal dystrophy, posterior amorphous |
|
|
| degenerative myopia |
|
|
| stromal dystrophy |
|
|
Search LUM in MalaCards
View complete list of genes associated with diseases
Additional Disease Information for LUM
- Human Genome Epidemiology Navigator
- (HuGE)
- Atlas
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
- Open Targets Platform
- Open Targets Platform
No data available for UniProtKB/Swiss-Prot and Genatlas for LUM Gene
Publications for LUM Gene
- Primary structure of human lumican (keratan sulfate proteoglycan) and localization of the gene (LUM) to chromosome 12q21.3-q22. (PMID: 7558030) Chakravarti S … Hassell JR (Genomics 1995) 2 3 4 22
- Association of the lumican gene functional 3'-UTR polymorphism with high myopia. (PMID: 19643966) Lin HJ … Tsai FJ (Investigative ophthalmology & visual science 2010) 3 22 40
- Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. (PMID: 20628086) Bailey SD … DREAM investigators (Diabetes care 2010) 3 40
- The association between lumican gene polymorphisms and high myopia. (PMID: 20010793) Lin HJ … Tsai FJ (Eye (London, England) 2010) 3 40
- High myopia is not associated with the SNPs in the TGIF, lumican, TGFB1, and HGF genes. (PMID: 19060265) Wang P … Zhang Q (Investigative ophthalmology & visual science 2009) 3 40
ExternalLinks
Products for LUM Gene
- View all 9 R&D Systems LUM (Lumican) Products
- View all R&D Systems LUM (Lumican) Proteins and Enzymes
- View all 5 R&D Systems LUM (Lumican) Primary Antibodies
- View all R&D Systems LUM (Lumican) ELISAs
- View all R&D Systems LUM (Lumican) Luminex Assays
- View all R&D Systems LUM (Lumican) Proteome Profiler Antibody Arrays
- Learn more about R&D Systems custom LUM antibody, protein, and immunoassay development services
- Custom Antibody Services
- Custom Assay Services
- Search Origene for MassSpec and Protein Over-expression Lysates for LUM
- Origene Custom Protein Services for LUM
- Origene shrna, sirna, and RNAi products in human, mouse, rat for LUM
- Browse OriGene Inhibitory RNA Products For LUM
- OriGene qPCR primer pairs for LUM
- OriGene qPCR primer pairs and template standards for LUM
- OriGene CRISPR knockouts for LUM
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For LUM
- Sino Biological Human cDNA Clone for LUM
- Sino Biological Recombinant Proteins for LUM
- Sino Biological Cell Lysates for LUM
- Sino Biological Antibodies for LUM
- Browse Sino Biological Assays
- Browse Recombinant Proteins
- Browse Antibodies
- Browse cDNA Clones
- Browse ELISA Kits
- Browse CRO Services
- High-throughput Antibody Production Service
- Protein Production Service
- Epitope Tag Antibodies & Reporter Protein Antibodies
- Lentiviral ORF Clones
- Novus Biologicals Antibodies for LUM
- Novus Biologicals proteins and lysates for LUM
- Browse Antibodies
- Browse Peptides and Proteins
- Browse Lysates
- Browse ELISA Kits
- Abcam antibodies for LUM
- Abcam proteins for LUM
- Abcam assays for LUM
- Find your target
- Browse Primary Antibodies
- Browse Conjugated Primary Antibodies
- Browse Secondary Antibodies
- Browse ELISA Kits
- Browse Matched Antibody Pairs
- Browse Proteins and Peptides
- Search Knockout (KO) Validated Antibodies
- Browse Monoclonal Antibodies
- Browse Recombinant Antibodies
- ProSpec Recombinant Proteins for LUM
- ESI BIO PureStem Z11, Meso Progenitor for LUM
- Invitrogen Antibodies for LUM (AFLGC-LUM)
- VectorBuilder Custom and pre-made DNA vectors for LUM (ie. gene expression, shRNA knockdown, CRISPR)
- VectorBuilder Viral vectors for LUM (ie. lentivirus, AAV, adenovirus)
- VectorBuilder CRISPR vectors for LUM (ie. knockout, knockin, CRISPRa, CRISPRi)
- VectorBuilder Virus packaging for LUM CRISPR vectors (ie. lentivirus, AAV, adenovirus)
- VectorBuilder Stable cell line generation for LUM
- antibodies-online: Show 19 available LUM Antibodies ranked by validation data
- Compare Top LUM Antibodies
- Recommended
- 62 WB Antibodies (anti-human)
- 12 IF (p) Antibodies (anti-human)
- 6 IHC Antibodies (anti-human)
- 2 IF/ICC Antibodies (anti-human)
- 2 RIA Antibodies (anti-human)
- 1 FACS Antibody (anti-human)
- 1 IHC (p) Antibody (anti-human)
- 38 WB Antibodies (anti-mouse)
- 12 IF (p) Antibodies (anti-mouse)
- 2 IHC Antibodies (anti-mouse)
- 21 WB Antibodies (anti-rat)
- 12 IF (p) Antibodies (anti-rat)
- 2 IHC Antibodies (anti-rat)
- antibodies-online: Show 53 available LUM Elisa Kits ranked by validation data
- Compare Top LUM Elisa Kits
- Quality Products:
- ABIN1115812
- ABIN367235
- ABIN414729
- ABIN1889401
- ABIN1029151
- ABIN5521080
- ABIN2708309
- ABIN4883685
- ABIN2684890
- ABIN5592320
- ABIN1889412
- ABIN843695
- ABIN4993562
- ABIN2708566
- ABIN6719824
- ABIN6205578
- ABIN6205579
- ABIN2684891
- ABIN6730202
- ABIN1141013
- ABIN1889413
- ABIN843696
- ABIN5521081
- ABIN2708668
- ABIN2684892
- ABIN5592321
- ABIN6719780
- ABIN2949194
- ABIN5071049
- ABIN1141014
- ABIN843697
- ABIN1141011
- antibodies-online: Show 21 available LUM Proteins ranked by validation data
- Compare Top LUM Proteins
- Santa Cruz Biotechnology (SCBT) Antibodies for LUM
- Search Santa Cruz Biotechnology (SCBT) for LUM siRNA/shRNA
- Santa Cruz Biotechnology (SCBT) CRISPR for LUM
- Custom Antibody ServicesProSci Antibodies for LUM
- ProSci Proteins for LUM
- Horizon Cell Lines for LUM
- Browse GeneCopoeia Cell Lines
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for LUM
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for LUM
- Search GeneCopoeia for miRNA 3'UTR Target clone products for LUM
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LUM
Sources for LUM Gene
- (1) GeneCards
- (2) HGNC
- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM® (Updated: 05-Apr-2021)
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) Cell Signaling Technology
- (12) GO
- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) ASD
- (27) SAGE
- (28) SOURCE
- (29) HomoloGene
- (30) PanEnsembl
- (31) euGenes
- (32) SGD
- (33) FlyBase
- (34) WormBase
- (35) Pseudogene
- (36) DGV
- (37) dbSNP
- (38) GenAtlas
- (39) HGMD
- (40) GAD
- (41) BGMUT
- (42) HuGE
- (43) Atlas
- (44) GenBank
- (45) HORDE
- (46) HUGE
- (47) IMGT
- (48) Leiden
- (49) miRBase
- (50) DME
- (51) OriGene
- (52) PubMed
- (53) R&D Systems
- (54) Tocris
- (55) Abcam
- (56) Novus Biologicals
- (57) ProSpec
- (58) Sino Biological
- (59) GenScript
- (60) Qiagen
- (61) OCA
- (62) Proteopedia
- (63) MOPED
- (64) neXtProt
- (65) Reactome
- (66) GeneGo (Thomson Reuters)
- (67) DISEASES
- (68) SIMAP
- (69) GenomeRNAi
- (70) LifeMap
- (71) miRTarBase
- (72) MalaCards
- (73) Invitrogen
- (74) BitterDB
- (75) ESI-BIO
- (76) RefSeq
- (77) BioSystems
- (78) MaxQB
- (79) IUPHAR
- (80) BioGPS
- (81) Illumina
- (82) COMPARTMENTS
- (83) HOMER
- (84) PaxDb
- (85) ApexBio
- (86) Addgene
- (87) antibodies-online
- (88) CYP
- (89) NONCODE
- (90) TreeFam
- (91) PathCards
- (92) GeneReviews
- (93) GeneTex
- (94) Taconic Biosciences
- (95) GTEx
- (96) ProteomicsDB
- (97) SCBT
- (98) DGIdb
- (99) ClinicalTrials
- (100) RVIS
- (101) SIGNOR
- (102) diseasecard
- (103) NIH Rare Diseases
- (104) Orphanet
- (105) UMLS
- (106) GTR
- (107) Disease Ontology
- (108) MedlinePlus Genetics
- (109) MeSH
- (110) MedlinePlus
- (111) CDC
- (112) NINDS
- (113) NCBI Bookshelf
- (114) ClinVar
- (115) Gene Damage Index
- (116) HPO
- (117) UDN
- (118) VISTA
- (119) FANTOM5
- (120) ENCODE
- (121) ProSci
- (122) Horizon
- (123) The Signaling Pathways Project (SPP)
- (124) IID
- (125) VectorBuilder
- (126) SNPedia
- (127) BRCA Exchange
- (128) CIViC
- (129) ProteoGenix
- (130) dbSUPER
- (131) TISSUES
- (132) Gene ORGANizer
- (133) abm
- (134) Human Protein Atlas
- (135) GWAS Catalog
- (136) Monarch Initiative
- (137) DataMed
- (138) HumanCyc
- (139) UCNEbase
- (140) EPDnew
- (141) Applied Biosystems
- (142) GlyConnect
- (143) Aminode
- (144) GeneCopoeia
- (145) GPS-Prot
- (146) RNAcentral
- (147) LncRNADisease
- (148) LOVD
- (149) miR2Disease
- (150) DiseaseEnhancer
- (151) Boster Bio
- (152) Biorbyt
- (153) Biocompare
- (154) Mastermind
- (155) CTD^2 Dashboard
- (156) CraniofacialAtlas
- (157) GeneImprint
- (158) Synthego
- (159) ENA
- (160) GtRNAdb
- (161) LncBase
- (162) LncBook
- (163) LNCipedia
- (164) Modomics
- (165) PDBe
- (166) Rfam
- (167) SILVA
- (168) snOPY
- (169) SRPDB
- (170) GENCODE
- (171) TarBase
- (172) Open Targets Platform
- (173) 5SRRNADB
- (174) snoDB
- (175) MirGeneDB
- (176) Alliance of Genome Resources