Aliases for LTO1 Gene
External Ids for LTO1 Gene
Previous HGNC Symbols for LTO1 Gene
GeneCards Summary for LTO1 Gene
LTO1 (LTO1 Maturation Factor Of ABCE1) is a Protein Coding gene. Diseases associated with LTO1 include Oral Cancer.
UniProtKB/Swiss-Prot Summary for LTO1 Gene
The complex LTO1:YAE1 functions as a target specific adapter that probably recruits apo-ABCE1 to the cytosolic iron-sulfur protein assembly (CIA) complex machinery (PubMed:26182403). May be required for biogenesis of the large ribosomal subunit and initiation of translation (PubMed:23318452). May play a role in the regulation of proline metabolism and ROS production (PubMed:24930674).