Aliases for LSG1 Gene
External Ids for LSG1 Gene
Previous GeneCards Identifiers for LSG1 Gene
This gene encodes a protein related to the yeast large subunit GTPase 1. The encoded protein is necessary for cell viability and may localize in the endoplasmic reticulum, nucleus and cytoplasm.[provided by RefSeq, Feb 2009]
GeneCards Summary for LSG1 Gene
LSG1 (Large 60S Subunit Nuclear Export GTPase 1) is a Protein Coding gene. Diseases associated with LSG1 include Parasitic Ectoparasitic Infectious Disease. Among its related pathways are Ribosome biogenesis in eukaryotes. Gene Ontology (GO) annotations related to this gene include GTP binding and GTPase activity. An important paralog of this gene is GNL1.
UniProtKB/Swiss-Prot for LSG1 Gene
GTPase required for the XPO1/CRM1-mediated nuclear export of the 60S ribosomal subunit. Probably acts by mediating the release of NMD3 from the 60S ribosomal subunit after export into the cytoplasm (Probable).