Aliases for LRRTM2 Gene
External Ids for LRRTM2 Gene
Previous GeneCards Identifiers for LRRTM2 Gene
GeneCards Summary for LRRTM2 Gene
LRRTM2 (Leucine Rich Repeat Transmembrane Neuronal 2) is a Protein Coding gene. Diseases associated with LRRTM2 include Histrionic Personality Disorder and Tarp Syndrome. Among its related pathways are Protein-protein interactions at synapses and Transmission across Chemical Synapses. Gene Ontology (GO) annotations related to this gene include neurexin family protein binding. An important paralog of this gene is LRIG1.
UniProtKB/Swiss-Prot Summary for LRRTM2 Gene
Involved in the development and maintenance of excitatory synapse in the vertebrate nervous system. Regulates surface expression of AMPA receptors and instructs the development of functional glutamate release sites. Acts as a ligand for the presynaptic receptors NRXN1-A and NRXN1-B (By similarity).