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LRRC8D (Leucine Rich Repeat Containing 8 VRAC Subunit D) is a Protein Coding gene. An important paralog of this gene is LRRC8A.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005225 | contributes_to volume-sensitive anion channel activity | IMP | 28193731 |
GO:0005515 | protein binding | IPI | 24790029 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005737 | cytoplasm | IDA | 24790029 |
GO:0005783 | endoplasmic reticulum | IEA | -- |
GO:0005789 | endoplasmic reticulum membrane | IEA | -- |
GO:0005886 | plasma membrane | TAS | -- |
GO:0005887 | integral component of plasma membrane | IMP | 26824658 |
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0006811 | ion transport | IEA | -- |
GO:0015698 | inorganic anion transport | IEA | -- |
GO:0015734 | taurine transport | IMP | 28193731 |
GO:0015810 | aspartate transmembrane transport | IMP | 28193731 |
GO:0055085 | transmembrane transport | TAS | -- |
ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | · | 9c | · | 9d | · | 9e |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
SP1: | - | - | - | - | - | - | - | ||||||||||||||||||||||
SP2: | - | - | - | ||||||||||||||||||||||||||
SP3: | - | - | - | - | - | - | - | - | |||||||||||||||||||||
SP4: | |||||||||||||||||||||||||||||
SP5: | - | - | - | - | - | - | |||||||||||||||||||||||
SP6: | - | - | |||||||||||||||||||||||||||
SP7: | - |
This gene was present in the common ancestor of chordates.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | LRRC8D 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | LRRC8D 30 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | LRRC8D 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Lrrc8d 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Lrrc8d 30 17 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | LRRC8D 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | LRRC8D 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | LRRC8D 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | lrrc8d 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | lrrc8db 30 31 |
|
OneToOne | |
Dr.19720 30 |
|
SNP ID | Clinical significance and condition | Chr 01 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs11552246 | - |
p.Ser371Tyr |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
esv3303537 | CNV | mobile element insertion | 20981092 |
esv3331862 | CNV | insertion | 20981092 |
esv3388679 | CNV | insertion | 20981092 |
esv3586772 | CNV | gain | 21293372 |
nsv1000666 | CNV | gain | 25217958 |
nsv1832 | CNV | deletion | 18451855 |
No disorders were found for LRRC8D Gene.