Aliases for LRRC8D Gene
Aliases for LRRC8D Gene
External Ids for LRRC8D Gene
- HGNC: 16992
- Entrez Gene: 55144
- Ensembl: ENSG00000171492
- OMIM: 612890
- UniProtKB: Q7L1W4
Previous HGNC Symbols for LRRC8D Gene
- LRRC5
Previous GeneCards Identifiers for LRRC8D Gene
- GC01P089999
- GC01P090060
- GC01P090286
- GC01P088403
Summaries for LRRC8D Gene
GeneCards Summary for LRRC8D Gene
LRRC8D (Leucine Rich Repeat Containing 8 VRAC Subunit D) is a Protein Coding gene. An important paralog of this gene is LRRC8A.
UniProtKB/Swiss-Prot for LRRC8D Gene
-
Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition (PubMed:24790029, PubMed:26824658). LRRC8A and LRRC8D are required for the uptake of the drug cisplatin (PubMed:26530471). Mediates the import of the antibiotic blasticidin-S into the cell (PubMed:24782309).
Additional gene information for LRRC8D Gene
- Monarch Initiative
- Search for LRRC8D at DataMed
- Search for LRRC8D at HumanCyc
No data available for Entrez Gene Summary , CIViC summary , Tocris Summary , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LRRC8D Gene
Genomics for LRRC8D Gene
GeneHancer (GH) Regulatory Elements for LRRC8D Gene
Promoters and enhancers for LRRC8D Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)
GeneHancers around LRRC8D on UCSC Golden Path with GeneCards custom track
- Top Transcription factor binding sites by QIAGEN in the LRRC8D gene promoter:
-
- NF-1
- Hlf
- AML1a
- Evi-1
- TBP
Regulatory Element Products
Genomic Locations for LRRC8D Gene
Genomic Locations for LRRC8D Gene
- chr1:89,821,014-89,936,611
- (GRCh38/hg38)
- Size:
- 115,598 bases
- Orientation:
- Plus strand
- chr1:90,286,573-90,402,170
- (GRCh37/hg19)
- Size:
- 115,598 bases
- Orientation:
- Plus strand
Genomic View for LRRC8D Gene
Genes around LRRC8D on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p22.2 by Entrez Gene
- 1p22.2 by HGNC
- 1p22.2 by Ensembl
LRRC8D Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for LRRC8D Gene
Proteins for LRRC8D Gene
-
Protein details for LRRC8D Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q7L1W4-LRC8D_HUMAN
- Recommended name:
- Volume-regulated anion channel subunit LRRC8D
- Protein Accession:
- Q7L1W4
- D3DT29
- Q6UWB2
- Q9NVW3
Protein attributes for LRRC8D Gene
- Size:
- 858 amino acids
- Molecular mass:
- 98201 Da
- Quaternary structure:
-
- Heterooligomer; heterooligomerizes with other LRRC8 proteins (LRRC8A, LRRC8B, LRRC8C and/or LRRC8E), possibly to form a heterohexamer (PubMed:24790029, PubMed:26824658). In vivo, the subunit composition may depend primarily on expression levels, and heterooligomeric channels containing various proportions of the different LRRC8 proteins may coexist (Probable).
- SequenceCaution:
-
- Sequence=AAQ89233.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=BAA91631.1; Type=Erroneous initiation; Evidence={ECO:0000305};
Protein Expression for LRRC8D Gene
Post-translational modifications for LRRC8D Gene
Other Protein References for LRRC8D Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Novus Biologicals Antibodies for LRRC8D
- Search GeneTex for Antibodies for LRRC8D
-
Santa Cruz Biotechnology (SCBT) Antibodies for LRRC8D
- Sino Biological Antibodies for LRRC8D
Protein Products
-
OriGene Purified Proteins for LRRC8D
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- Search GeneTex for Proteins for LRRC8D
-
Abcam proteins for LRRC8D
Assay Products
No data available for DME Specific Peptides for LRRC8D Gene
Domains & Families for LRRC8D Gene
Gene Families for LRRC8D Gene
- HGNC:
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
- Predicted membrane proteins
- Transporters
Protein Domains for LRRC8D Gene
- InterPro:
- ProtoNet:
Suggested Antigen Peptide Sequences for LRRC8D Gene
- GenScript: Design optimal peptide antigens:
Graphical View of Domain Structure for InterPro Entry
Q7L1W4- Family:
-
- Belongs to the LRRC8 family.
Function for LRRC8D Gene
Molecular function for LRRC8D Gene
- UniProtKB/Swiss-Prot Function:
- Non-essential component of the volume-regulated anion channel (VRAC, also named VSOAC channel), an anion channel required to maintain a constant cell volume in response to extracellular or intracellular osmotic changes. The VRAC channel conducts iodide better than chloride and may also conduct organic osmolytes like taurine. Channel activity requires LRRC8A plus at least one other family member (LRRC8B, LRRC8C, LRRC8D or LRRC8E); channel characteristics depend on the precise subunit composition (PubMed:24790029, PubMed:26824658). LRRC8A and LRRC8D are required for the uptake of the drug cisplatin (PubMed:26530471). Mediates the import of the antibiotic blasticidin-S into the cell (PubMed:24782309).
Phenotypes From GWAS Catalog for LRRC8D Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005225 | volume-sensitive anion channel activity | TAS | -- |
| GO:0005515 | protein binding | IPI | 24790029 |
Phenotypes for LRRC8D Gene
Animal Model Products
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-
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-
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miRNA for LRRC8D Gene
- miRTarBase miRNAs that target LRRC8D
-
- hsa-mir-1-3p (MIRT023944)
- hsa-mir-26b-5p (MIRT029937)
- hsa-mir-454-3p (MIRT039220)
- hsa-mir-615-3p (MIRT040025)
- hsa-mir-30a-5p (MIRT149112)
- hsa-mir-30c-5p (MIRT149115)
- hsa-mir-30d-5p (MIRT149116)
- hsa-mir-181a-5p (MIRT149117)
- hsa-mir-181b-5p (MIRT149118)
- hsa-mir-181c-5p (MIRT149119)
- hsa-mir-30b-5p (MIRT149121)
- hsa-mir-30e-5p (MIRT149122)
- hsa-mir-181d-5p (MIRT149123)
miRNA Products
Inhibitory RNA Products
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-
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-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
Cell Line Products
-
Horizon Cell Lines for LRRC8D
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for LRRC8D Gene
Localization for LRRC8D Gene
Subcellular locations from UniProtKB/Swiss-Prot for LRRC8D Gene
- Cell membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane. Note=In the absence of LRRC8A, resides primarily in a cytoplasmic compartment, probably the endoplasmic reticulum (PubMed:24782309, PubMed:24790029). Requires LRRC8A for expression at the cell membrane (PubMed:24790029). {ECO:0000269 PubMed:24782309, ECO:0000269 PubMed:24790029}.
| Compartment | Confidence |
|---|---|
| plasma membrane | 5 |
| endoplasmic reticulum | 4 |
| nucleus | 3 |
| mitochondrion | 2 |
| peroxisome | 1 |
| cytosol | 1 |
- Mitochondria (2)
- Nucleoplasm (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005737 | cytoplasm | IDA | 24790029 |
| GO:0005783 | endoplasmic reticulum | IEA | -- |
| GO:0005789 | endoplasmic reticulum membrane | IEA | -- |
| GO:0005886 | plasma membrane | TAS | -- |
| GO:0005887 | integral component of plasma membrane | IMP | 26824658 |
Pathways & Interactions for LRRC8D Gene
No Data Available
Interacting Proteins for LRRC8D Gene
Selected Interacting proteins:
ENSP00000338887
Q7L1W4-LRC8D_HUMAN
for LRRC8D Gene via
STRING
UniProtKB
IID
GPS-Prot Interaction Network for LRRC8D
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006811 | ion transport | IEA | -- |
| GO:0007165 | signal transduction | IBA | -- |
| GO:0015698 | inorganic anion transport | IEA | -- |
| GO:0055085 | transmembrane transport | TAS | -- |
| GO:0098656 | anion transmembrane transport | IMP | 24790029 |
No data available for Pathways by source and SIGNOR curated interactions for LRRC8D Gene
Transcripts for LRRC8D Gene
mRNA/cDNA for LRRC8D Gene
- (5) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (126) Selected AceView cDNA sequences:
- (7) Ensembl transcripts including schematic representations, and UCSC links where relevant :
-
- ENST00000525774 588 bps (uc057ifb.1)
- ENST00000337338 3950 bps (uc001dnm.4)
- ENST00000394593 3345 bps (uc001dnn.4)
- ENST00000532201 597 bps (uc057ifc.1)
- ENST00000414841 666 bps (uc057ifd.1)
Unigene Clusters for LRRC8D Gene
- Leucine rich repeat containing 8 family, member D:
- Representative Sequences:
CRISPR Products
-
OriGene CRISPR knockouts for LRRC8D
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- Applied Biological Materials CRISPR for LRRC8D
-
Vectors and viruses for KO, Activation, Repression, and more
-
Santa Cruz Biotechnology (SCBT) CRISPR for LRRC8D
- GenScript: Design CRISPR guide RNA sequences for LRRC8D
miRNA Products
Inhibitory RNA Products
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Clone Products
-
OriGene ORF clones in human for LRRC8D
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- Applied Biological Materials Clones for LRRC8D
-
Vectors and viruses for ORF, Lenti, Retro, Adenovirus, AAV, and more
| ExUns: | 1 | ^ | 2a | · | 2b | ^ | 3 | ^ | 4 | ^ | 5 | ^ | 6a | · | 6b | ^ | 7 | ^ | 8 | ^ | 9a | · | 9b | · | 9c | · | 9d | · | 9e |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | - | - | - | - | - | - | ||||||||||||||||||||||
| SP2: | - | - | - | ||||||||||||||||||||||||||
| SP3: | - | - | - | - | - | - | - | - | |||||||||||||||||||||
| SP4: | |||||||||||||||||||||||||||||
| SP5: | - | - | - | - | - | - | |||||||||||||||||||||||
| SP6: | - | - | |||||||||||||||||||||||||||
| SP7: | - |
Expression for LRRC8D Gene
mRNA expression in embryonic tissues and stem cells from LifeMap Discovery
-
Placenta (Extraembryonic Tissues)
- Primordial Germ Cells Allantois
-
Gonad
- Primordial Germ Cells Allantois
This gene is overexpressed in Adrenal (43.8), Lung (13.5), and Peripheral blood mononuclear cells (7.1).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for LRRC8D Gene
NURSA nuclear receptor signaling pathways regulating expression of LRRC8D Gene:
LRRC8DSOURCE GeneReport for Unigene cluster for LRRC8D Gene:
Hs.482087Evidence on tissue expression from TISSUES for LRRC8D Gene
- Nervous system(2.5)
Primer Products
-
OriGene qPCR primer pairs for LRRC8D
-
OriGene qPCR primer pairs and template standards for LRRC8D
Gene Expression Assay Products
No data available for mRNA differential expression in normal tissues , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt and Phenotype-based relationships between genes and organs from Gene ORGANizer for LRRC8D Gene
Orthologs for LRRC8D Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | LRRC8D 34 33 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | LRRC8D 34 33 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | LRRC8D 34 33 |
|
OneToOne | |
| rat (Rattus norvegicus) |
Mammalia | Lrrc8d 33 |
|
||
| mouse (Mus musculus) |
Mammalia | Lrrc8d 16 34 33 |
|
||
| platypus (Ornithorhynchus anatinus) |
Mammalia | LRRC8D 34 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | LRRC8D 34 33 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | LRRC8D 34 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | lrrc8d 33 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | lrrc8db 34 33 |
|
OneToOne | |
| Dr.19720 33 |
|
- Species where no ortholog for LRRC8D was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- oppossum (Monodelphis domestica)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for LRRC8D Gene
- ENSEMBL:
- Gene Tree for LRRC8D (if available)
- TreeFam:
- Gene Tree for LRRC8D (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for LRRC8D: view image
Paralogs for LRRC8D Gene
Paralogs for LRRC8D Gene
(7) SIMAP similar genes for LRRC8D Gene using alignment to 7 proteins:
- LRC8D_HUMAN
- E9PJ89_HUMAN
- E9PJS7_HUMAN
- E9PL08_HUMAN
- E9PMF9_HUMAN
- Q5VWA0_HUMAN
- Q96GG5_HUMAN
Variants for LRRC8D Gene
| SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000025483 | -- | 89,821,379(+) | C/G | 5_prime_UTR_variant, genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant | |
| rs1000037636 | -- | 89,864,004(+) | A/G | intron_variant | |
| rs1000053139 | -- | 89,877,600(+) | G/A | intron_variant | |
| rs1000056223 | -- | 89,906,691(+) | A/G | intron_variant | |
| rs1000056682 | -- | 89,821,482(+) | T/G | 5_prime_UTR_variant, genic_upstream_transcript_variant, intron_variant, upstream_transcript_variant |
| Variant ID | Type | Subtype | PubMed ID |
|---|---|---|---|
| esv3303537 | CNV | mobile element insertion | 20981092 |
| esv3331862 | CNV | insertion | 20981092 |
| esv3388679 | CNV | insertion | 20981092 |
| esv3586772 | CNV | gain | 21293372 |
| nsv1000666 | CNV | gain | 25217958 |
| nsv1832 | CNV | deletion | 18451855 |
Residual Variation Intolerance Score:
8.35% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
1.68;
32.01% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for LRRC8D Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- LRRC8D
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LRRC8D Gene
Disorders for LRRC8D Gene
Additional Disease Information for LRRC8D
- Genetic Association Database
- (GAD)
- Human Genome Epidemiology Navigator
- (HuGE)
- ATLAS of Genetics and Cytogenetics in Oncology and Haematology
No disorders were found for LRRC8D Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for LRRC8D Gene
Publications for LRRC8D Gene
- Identification of LRRC8 heteromers as an essential component of the volume-regulated anion channel VRAC. (PMID: 24790029) Voss FK … Jentsch TJ (Science (New York, N.Y.) 2014) 2 3 4 58
- LRRC8 Proteins Form Volume-Regulated Anion Channels that Sense Ionic Strength. (PMID: 26824658) Syeda R … Patapoutian A (Cell 2016) 3 4 58
- The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4 58
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 58
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 58
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- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for LRRC8D
- GeneCopoeia miRNA 3'UTR Target clone products for LRRC8D
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LRRC8D
Sources for LRRC8D Gene
- (1) GeneCards
- (2) HGNC
- (3) EntrezGene
- (4) Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
- (9) UCSC
- (10) PhosphoSitePlus
- (11) GO
- (12) TrEMBL
- (13) InterPro
- (14) ProtoNet
- (15) Blocks
- (16) MGI
- (17) IUBMB
- (18) KEGG
- (19) MINT
- (20) STRING
- (21) IntAct
- (22) Novoseek
- (23) PharmGKB
- (24) DrugBank
- (25) HMDB
- (26) UniGene
- (27) AceView
- (28) ASD
- (29) ECgene
- (30) GeneAnnot
- (31) CGAP SAGE
- (32) SOURCE
- (33) HomoloGene
- (34) PanEnsembl
- (35) euGenes
- (36) SGD
- (37) FlyBase
- (38) WormBase
- (39) Pseudogene
- (40) DGV
- (41) dbSNP
- (42) GenAtlas
- (43) HGMD
- (44) GAD
- (45) BGMUT
- (46) HuGE
- (47) Atlas
- (48) Cell Signaling Technology
- (49) GenBank
- (50) H-invDB
- (51) HORDE
- (52) HUGE
- (53) IMGT
- (54) Leiden
- (55) miRBase
- (56) DME
- (57) OriGene
- (58) PubMed
- (59) R&D Systems
- (60) TGDB
- (61) Tocris
- (62) Abcam
- (63) Novus Biologicals
- (64) ProSpec
- (65) Sino Biological
- (66) GenScript
- (67) Qiagen
- (68) Cloud-Clone Corp.
- (69) OCA
- (70) Proteopedia
- (71) MOPED
- (72) neXtProt
- (73) Reactome
- (74) GeneGo (Thomson Reuters)
- (75) fRNAdb
- (76) DISEASES
- (77) SIMAP
- (78) GenomeRNAi
- (79) LifeMap
- (80) miRTarBase
- (81) MalaCards
- (82) Invitrogen
- (83) BitterDB
- (84) Vector BioLabs
- (85) ESI-BIO
- (86) RefSeq
- (87) BioSystems
- (88) MaxQB
- (89) IUPHAR
- (90) BioGPS
- (91) Illumina
- (92) COMPARTMENTS
- (93) HOMER
- (94) PaxDb
- (95) ApexBio
- (96) Addgene
- (97) antibodies-online
- (98) CYP
- (99) NONCODE
- (100) SwitchGear Genomics
- (101) TreeFam
- (102) PathCards
- (103) GeneReviews
- (104) GeneTex
- (105) Taconic Biosciences
- (106) GTEx
- (107) ProteomicsDB
- (108) SCBT
- (109) DGIdb
- (110) ClinicalTrials
- (111) FDA Approved Drugs
- (112) RVIS
- (113) SIGNOR
- (114) diseasecard
- (115) NIH Rare Diseases
- (116) Orphanet
- (117) UMLS
- (118) GTR
- (119) Disease Ontology
- (120) Genetics Home Reference
- (121) MeSH
- (122) MedlinePlus
- (123) CDC
- (124) NINDS
- (125) NCBI Bookshelf
- (126) ClinVar
- (127) Gene Damage Index
- (128) ViGene Biosciences
- (129) HPO
- (130) UDN
- (131) VISTA
- (132) FANTOM5
- (133) ENCODE
- (134) ProSci
- (135) Horizon
- (136) NURSA
- (137) IID
- (138) Cyagen
- (139) VectorBuilder
- (140) SNPedia
- (141) BRCA Exchange
- (142) St John's Lab
- (143) CIViC
- (144) ProteoGenix
- (145) dbSUPER
- (146) TISSUES
- (147) Gene ORGANizer
- (148) abm
- (149) CrownBio
- (150) Human Protein Atlas
- (151) GWAS Catalog
- (152) Monarch Initiative
- (153) DataMed
- (154) HumanCyc
- (155) genomics-online
- (156) UCNEbase
- (157) EPDnew
- (158) Applied Biosystems
- (159) GlyConnect
- (160) Aminode
- (161) GeneCopoeia
- (162) GPS-Prot
- (163) RNACentral
- (164) LncRNADisease
- (165) LOVD
- (166) miR2Disease
- (167) DiseaseEnhancer
- (168) Boster Bio
- (169) Biorbyt