Aliases for LRRC6 Gene
External Ids for LRRC6 Gene
Previous GeneCards Identifiers for LRRC6 Gene
The protein encoded by this gene contains several leucine-rich repeat domains and appears to be involved in the motility of cilia. Defects in this gene are a cause of primary ciliary dyskinesia-19 (CILD19). Alternative splicing of this gene results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 4, 11 and 22. [provided by RefSeq, Apr 2016]
GeneCards Summary for LRRC6 Gene
LRRC6 (Leucine Rich Repeat Containing 6) is a Protein Coding gene. Diseases associated with LRRC6 include Ciliary Dyskinesia, Primary, 19 and Ciliary Dyskinesia, Primary, 1. An important paralog of this gene is LRRC9.
UniProtKB/Swiss-Prot Summary for LRRC6 Gene
May play a role in dynein arm assembly, hence essential for proper axoneme building for cilia motility.