Aliases for LRRC2 Gene
External Ids for LRRC2 Gene
Previous GeneCards Identifiers for LRRC2 Gene
This gene encodes a member of the leucine-rich repeat-containing family of proteins, which function in diverse biological pathways. This family member may possibly be a nuclear protein. Similarity to the RAS suppressor protein, as well as expression down-regulation observed in tumor cells, suggests that it may function as a tumor suppressor. The gene is located in the chromosome 3 common eliminated region 1 (C3CER1), a 1.4 Mb region that is commonly deleted in diverse tumors. A related pseudogene has been identified on chromosome 2. [provided by RefSeq, Sep 2011]
GeneCards Summary for LRRC2 Gene
LRRC2 (Leucine Rich Repeat Containing 2) is a Protein Coding gene. Diseases associated with LRRC2 include Severe Combined Immunodeficiency and Ullrich Congenital Muscular Dystrophy 1. An important paralog of this gene is LRRC39.