Aliases for LRP12 Gene
External Ids for LRP12 Gene
Previous GeneCards Identifiers for LRP12 Gene
This gene encodes a member of the low-density lipoprotein receptor related protein family. The product of this gene is a transmembrane protein that is differentially expressed in many cancer cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]
GeneCards Summary for LRP12 Gene
LRP12 (LDL Receptor Related Protein 12) is a Protein Coding gene. Diseases associated with LRP12 include Oculopharyngodistal Myopathy 1 and Neuronal Intranuclear Inclusion Disease. Among its related pathways are Signaling by GPCR and Metabolism of fat-soluble vitamins. Gene Ontology (GO) annotations related to this gene include low-density lipoprotein particle receptor activity. An important paralog of this gene is LRP3.
UniProtKB/Swiss-Prot Summary for LRP12 Gene
Probable receptor, which may be involved in the internalization of lipophilic molecules and/or signal transduction. May act as a tumor suppressor.