Aliases for LRIF1 Gene
Aliases for LRIF1 Gene
- Ligand Dependent Nuclear Receptor Interacting Factor 1 2 3 5
- HP1-Binding Protein Enriched In Inactive X Chromosome Protein 1 3 4
- Ligand-Dependent Nuclear Receptor-Interacting Factor 1 3 4
- Receptor-Interacting Factor 1 3 4
- C1orf103 3 4
- HBiX1 3 4
- RIF1 3 4
- Chromosome 1 Open Reading Frame 103 2
- Receptor Interacting Factor 1 2
External Ids for LRIF1 Gene
- HGNC: 30299
- Entrez Gene: 55791
- Ensembl: ENSG00000121931
- OMIM: 615354
- UniProtKB: Q5T3J3
Previous HGNC Symbols for LRIF1 Gene
- C1orf103
Previous GeneCards Identifiers for LRIF1 Gene
- GC01M111491
- GC01M110877
Summaries for LRIF1 Gene
GeneCards Summary for LRIF1 Gene
LRIF1 (Ligand Dependent Nuclear Receptor Interacting Factor 1) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include retinoic acid receptor binding.
UniProtKB/Swiss-Prot Summary for LRIF1 Gene
-
Together with SMCHD1, involved in chromosome X inactivation in females by promoting the compaction of heterochromatin (PubMed:23542155). Also able to repress the ligand-induced transcriptional activity of retinoic acid receptor alpha (RARA), possibly through direct recruitment of histone deacetylases (PubMed:17455211).
No data available for Entrez Gene Summary , CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for LRIF1 Gene
Genomics for LRIF1 Gene
GeneHancer (GH) Regulatory Elements for LRIF1 Gene
Promoters and enhancers for LRIF1 Gene
- Elite GeneHancer and/or Elite GeneHancer-gene association
Download GeneHancer data from 2017 publication |
Request up-to-date GeneHancer data (full dataset)
GeneHancers around LRIF1 on UCSC Golden Path with GeneCards custom track
Genomic Locations for LRIF1 Gene
Genomic Locations for LRIF1 Gene
- chr1:110,947,190-110,964,197
- (GRCh38/hg38)
- Size:
- 17,008 bases
- Orientation:
- Minus strand
- chr1:111,489,807-111,506,701
- (GRCh37/hg19)
- Size:
- 16,895 bases
- Orientation:
- Minus strand
Genomic View for LRIF1 Gene
Genes around LRIF1 on UCSC Golden Path with GeneCards custom track
- Cytogenetic band:
-
- 1p13.3 by HGNC
- 1p13.3 by Entrez Gene
- 1p13.3 by Ensembl
LRIF1 Gene in genomic location: bands according to
Ensembl, locations according to GeneLoc
(and/or Entrez Gene and/or Ensembl if different)
Genomic Neighborhood
• Exon Structure
• Gene Density
RefSeq DNA sequence for LRIF1 Gene
Proteins for LRIF1 Gene
-
Protein details for LRIF1 Gene (UniProtKB/Swiss-Prot)
- Protein Symbol:
- Q5T3J3-LRIF1_HUMAN
- Recommended name:
- Ligand-dependent nuclear receptor-interacting factor 1
- Protein Accession:
- Q5T3J3
- Q86XS4
- Q8N3B6
- Q96HT4
- Q9NUM5
- Q9NV32
Protein attributes for LRIF1 Gene
- Size:
- 769 amino acids
- Molecular mass:
- 84568 Da
- Quaternary structure:
-
- Interacts with RARA (PubMed:17455211). Interacts with SMCHD1; leading to recruitment to inactivated chromosome X in females (PubMed:23542155). Interacts (via PxVxL motif) with HP1 (CBX1/HP1-beta, CBX3/HP1-gamma and CBX5/HP1-alpha) (PubMed:23542155).
- SequenceCaution:
-
- Sequence=AAH08115.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=AAO43631.1; Type=Frameshift; Positions=23; Evidence={ECO:0000305}; Sequence=BAA92097.1; Type=Frameshift; Positions=667; Evidence={ECO:0000305};
Protein Expression for LRIF1 Gene
Post-translational modifications for LRIF1 Gene
Other Protein References for LRIF1 Gene
- ENSEMBL proteins:
- REFSEQ proteins:
Antibody Products
- Atlas Antibodies Anti-LRIF1 Antibody
- Novus Biologicals Antibodies for LRIF1
-
Abcam antibodies for LRIF1
- Invitrogen Antibodies for LRIF1 (AFLGC-LRIF1)
Protein Products
- Atlas Antibodies PrEST Antigen LRIF1
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for LRIF1
- Origene Custom Protein Services for LRIF1
-
Abcam proteins for LRIF1
No data available for DME Specific Peptides for LRIF1 Gene
Domains & Families for LRIF1 Gene
Gene Families for LRIF1 Gene
- Human Protein Atlas (HPA):
-
- Predicted intracellular proteins
Suggested Antigen Peptide Sequences for LRIF1 Gene
- GenScript: Design optimal peptide antigens:
-
- Receptor-interacting factor 1 (LRIF1_HUMAN)
Graphical View of Domain Structure for InterPro Entry
Q5T3J3UniProtKB/Swiss-Prot:
LRIF1_HUMAN :- The Pro-Xaa-Val-Xaa-Leu (PxVxL) motif mediates interaction with HP1 (CBX1/HP1-beta, CBX3/HP1-gamma and CBX5/HP1-alpha).
- Belongs to the LRIF1 family.
- Domain:
-
- The Pro-Xaa-Val-Xaa-Leu (PxVxL) motif mediates interaction with HP1 (CBX1/HP1-beta, CBX3/HP1-gamma and CBX5/HP1-alpha).
- Family:
-
- Belongs to the LRIF1 family.
Function for LRIF1 Gene
Molecular function for LRIF1 Gene
- UniProtKB/Swiss-Prot Function:
- Together with SMCHD1, involved in chromosome X inactivation in females by promoting the compaction of heterochromatin (PubMed:23542155). Also able to repress the ligand-induced transcriptional activity of retinoic acid receptor alpha (RARA), possibly through direct recruitment of histone deacetylases (PubMed:17455211).
Phenotypes From GWAS Catalog for LRIF1 Gene
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0005515 | protein binding | IPI | 15383276 |
| GO:0042974 | retinoic acid receptor binding | IEA | -- |
Phenotypes for LRIF1 Gene
Animal Model Products
- Taconic Biosciences: Generate A Custom CRISPR Mouse Model For Your Study
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for LRIF1 - Select products 50% OFF >
- * LRIF1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * LRIF1 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
OriGene CRISPR knockouts for LRIF1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for LRIF1
- genomics-online: gRNA clones - Search results for available C1orf103 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for LRIF1
miRNA for LRIF1 Gene
- miRTarBase miRNAs that target LRIF1
-
- hsa-mir-155-5p (MIRT020641)
- hsa-mir-4310 (MIRT178982)
- hsa-mir-7157-5p (MIRT178984)
- hsa-mir-4668-5p (MIRT544250)
- hsa-mir-3152-5p (MIRT544251)
- hsa-mir-6514-3p (MIRT544252)
- hsa-mir-4774-3p (MIRT544253)
- hsa-mir-6894-3p (MIRT544254)
- hsa-mir-661 (MIRT544255)
- hsa-mir-3116 (MIRT544256)
- hsa-mir-1254 (MIRT544257)
- hsa-mir-107 (MIRT544258)
- hsa-mir-103a-3p (MIRT544259)
- hsa-mir-186-3p (MIRT544260)
- hsa-mir-3613-3p (MIRT544261)
- hsa-mir-5588-3p (MIRT544262)
- hsa-mir-548e-5p (MIRT544263)
- hsa-mir-1258 (MIRT619202)
- hsa-mir-6829-3p (MIRT619203)
- hsa-mir-6791-3p (MIRT619204)
- hsa-mir-1976 (MIRT619205)
- hsa-mir-3653-5p (MIRT619206)
- hsa-mir-6747-3p (MIRT619207)
- hsa-mir-6727-3p (MIRT619208)
- hsa-mir-4722-3p (MIRT619209)
- hsa-mir-6739-3p (MIRT645898)
- hsa-mir-3658 (MIRT645899)
- hsa-mir-4677-5p (MIRT645900)
- hsa-mir-7156-5p (MIRT645901)
- hsa-mir-2117 (MIRT645902)
- hsa-mir-4273 (MIRT645903)
- hsa-mir-5193 (MIRT645904)
- hsa-mir-660-3p (MIRT645905)
- hsa-mir-4279 (MIRT663053)
- hsa-mir-6882-3p (MIRT663054)
- hsa-mir-4524a-3p (MIRT663055)
- hsa-mir-7157-3p (MIRT663056)
- hsa-mir-6737-3p (MIRT663057)
- hsa-mir-5008-3p (MIRT663058)
- hsa-mir-1304-3p (MIRT663059)
- hsa-mir-1208 (MIRT663060)
- hsa-mir-6760-3p (MIRT663061)
- hsa-mir-1182 (MIRT663062)
- hsa-mir-4524b-3p (MIRT663063)
- hsa-mir-5089-5p (MIRT687632)
- hsa-mir-6807-5p (MIRT687633)
- hsa-mir-5589-5p (MIRT687634)
- hsa-mir-4731-5p (MIRT687635)
- hsa-mir-6778-3p (MIRT687636)
- hsa-mir-4252 (MIRT687637)
- hsa-mir-6506-5p (MIRT687638)
- hsa-mir-619-5p (MIRT687639)
- hsa-mir-150-5p (MIRT687640)
- hsa-mir-7107-5p (MIRT687641)
- hsa-mir-1234-3p (MIRT687642)
- hsa-mir-1273g-3p (MIRT687643)
- hsa-mir-520h (MIRT687644)
- hsa-mir-520g-3p (MIRT687645)
- hsa-mir-6504-3p (MIRT687646)
- hsa-mir-512-3p (MIRT687647)
- hsa-mir-576-3p (MIRT687648)
- hsa-mir-5683 (MIRT687649)
- hsa-mir-520e (MIRT687650)
- hsa-mir-520d-3p (MIRT687651)
- hsa-mir-520c-3p (MIRT687652)
- hsa-mir-520b (MIRT687653)
- hsa-mir-520a-3p (MIRT687654)
- hsa-mir-373-3p (MIRT687655)
- hsa-mir-372-3p (MIRT687656)
- hsa-mir-302e (MIRT687657)
- hsa-mir-302d-3p (MIRT687658)
- hsa-mir-302c-3p (MIRT687659)
- hsa-mir-302b-3p (MIRT687660)
- hsa-mir-302a-3p (MIRT687661)
- hsa-mir-93-5p (MIRT687662)
- hsa-mir-526b-3p (MIRT687663)
- hsa-mir-519d-3p (MIRT687664)
- hsa-mir-20b-5p (MIRT687665)
- hsa-mir-20a-5p (MIRT687666)
- hsa-mir-17-5p (MIRT687667)
- hsa-mir-106b-5p (MIRT687668)
- hsa-mir-106a-5p (MIRT687669)
- hsa-mir-195-5p (MIRT728125)
- hsa-mir-16-5p (MIRT728126)
- hsa-mir-15a-5p (MIRT728127)
- hsa-mir-15b-5p (MIRT728128)
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for LRIF1
- Browse OriGene Inhibitory RNA Products For LRIF1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LRIF1
- genomics-online: shRNA clones - Search results for available C1orf103 gene related products
Clone Products
- Applied Biological Materials (abm): Clones for LRIF1 - Select products 50% OFF >
- * LRIF1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * LRIF1 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
-
- MG213437
- MG214341
- MG214420
- MR213437
- MR213437L3
- MR213437L3V
- MR213437L4
- MR213437L4V
- MR214341
- MR214341L3
- MR214341L3V
- MR214341L4
- MR214341L4V
- MR214420
- MR214420L3
- MR214420L3V
- MR214420L4
- MR214420L4V
- MR228702
- RC203729
- RC203729L3
- RC203729L3V
- RC203729L4
- RC203729L4V
- RC213259
- RC213259L3
- RC213259L3V
- RC213259L4
- RC213259L4V
- RG203729
- RG213259
- RR208879
- RR208879L3
- RR208879L3V
- RR208879L4
- RR208879L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for LRIF1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for LRIF1
- genomics-online: cdna clones - Search results for available C1orf103 gene related products
- orf clones - Search results for available C1orf103 gene related products
Cell Line Products
-
Horizon Cell Lines for LRIF1
No data available for Enzyme Numbers (IUBMB) , Human Phenotype Ontology , Animal Models , Transcription Factor Targets and HOMER Transcription for LRIF1 Gene
Localization for LRIF1 Gene
Subcellular locations from UniProtKB/Swiss-Prot for LRIF1 Gene
- Chromosome. Nucleus matrix. Note=Localizes to Barr body; recruited by SMCHD1. {ECO:0000269 PubMed:23542155}.
| Compartment | Confidence |
|---|---|
| nucleus | 5 |
| cytoskeleton | 4 |
| cytosol | 2 |
- Nucleus (3)
- Microtubule organizing center (2)
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0000784 | colocalizes_with nuclear chromosome, telomeric region | IDA | 24270157 |
| GO:0001740 | Barr body | IDA | 23542155 |
| GO:0005634 | nucleus | IDA,IBA | -- |
| GO:0005694 | chromosome | IEA | -- |
| GO:0005815 | microtubule organizing center | IDA | -- |
Pathways & Interactions for LRIF1 Gene
Interacting Proteins for LRIF1 Gene
Selected Interacting proteins:
Q5T3J3-LRIF1_HUMAN
ENSP00000358778
for LRIF1 Gene via
UniProtKB
MINT
STRING
IID
GPS-Prot Interaction Network for LRIF1
| GO ID | Qualified GO term | Evidence | PubMed IDs |
|---|---|---|---|
| GO:0006355 | regulation of transcription, DNA-templated | IEA | -- |
| GO:0009048 | dosage compensation by inactivation of X chromosome | IMP | 23542155 |
No data available for Pathways by source and SIGNOR curated interactions for LRIF1 Gene
Drugs & Compounds for LRIF1 Gene
No Compound Related Data Available
Drug Products
- Atlas Antibodies PrEST Antigen LRIF1
Transcripts for LRIF1 Gene
mRNA/cDNA for LRIF1 Gene
- (2) REFSEQ mRNAs :
- (9) Additional mRNA sequences :
- (144) Selected AceView cDNA sequences:
- (3) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :
-
- ENST00000369763 3313 bps (ENST00000369763.4)
- ENST00000494675 1912 bps (ENST00000494675.5)
- ENST00000485275 1796 bps (ENST00000485275.2)
CRISPR Products
- Applied Biological Materials (abm): CRISPR Clones for LRIF1 - Select products 50% OFF >
- * LRIF1 CRISPR as ready-to-use vector or virus: ORF | Lenti- | Adeno- | AAV- | Protein Vector - Browse All
- * LRIF1 CRISPR applications: KO, Activation, Repression, and more - Browse All
-
OriGene CRISPR knockouts for LRIF1
- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for LRIF1
- genomics-online: gRNA clones - Search results for available C1orf103 gene related products
-
Santa Cruz Biotechnology (SCBT) CRISPR for LRIF1
miRNA Products
Inhibitory RNA Products
- Origene sirna, shrna, and RNAi products in human, mouse, rat for LRIF1
- Browse OriGene Inhibitory RNA Products For LRIF1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LRIF1
- genomics-online: shRNA clones - Search results for available C1orf103 gene related products
Clone Products
- Applied Biological Materials (abm): Clones for LRIF1 - Select products 50% OFF >
- * LRIF1 as ready-to-use vector or virus: ORF | Lenti- | Retro- | Adeno- | AAV- | Protein Vector - Browse All
- * LRIF1 tags and reporters available: His, HA, Myc, Flag, GFP, RFP, Luciferase - Browse All
-
- MG213437
- MG214341
- MG214420
- MR213437
- MR213437L3
- MR213437L3V
- MR213437L4
- MR213437L4V
- MR214341
- MR214341L3
- MR214341L3V
- MR214341L4
- MR214341L4V
- MR214420
- MR214420L3
- MR214420L3V
- MR214420L4
- MR214420L4V
- MR228702
- RC203729
- RC203729L3
- RC203729L3V
- RC203729L4
- RC203729L4V
- RC213259
- RC213259L3
- RC213259L3V
- RC213259L4
- RC213259L4V
- RG203729
- RG213259
- RR208879
- RR208879L3
- RR208879L3V
- RR208879L4
- RR208879L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Sino Biological Human cDNA Clone for LRIF1
- Search GeneCopoeia for ORF cDNA, lentivirus, AAV viral particles and/or promoter clone products for LRIF1
- genomics-online: cdna clones - Search results for available C1orf103 gene related products
- orf clones - Search results for available C1orf103 gene related products
| ExUns: | 1a | · | 1b | · | 1c | ^ | 2 | ^ | 3 |
|---|---|---|---|---|---|---|---|---|---|
| SP1: | - | ||||||||
| SP2: |
Expression for LRIF1 Gene
This gene is overexpressed in Testis (19.9), Retina (13.0), Blymphocyte (11.8), Spinal cord (9.2), and CD8 Tcells (8.2).
Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for LRIF1 Gene
NURSA nuclear receptor signaling pathways regulating expression of LRIF1 Gene:
LRIF1SOURCE GeneReport for Unigene cluster for LRIF1 Gene:
Hs.25245mRNA Expression by UniProt/SwissProt for LRIF1 Gene:
Q5T3J3-LRIF1_HUMAN
Tissue specificity:
Widely expressed, with the highest expression levels in heart, liver and placenta.
Primer Products
-
OriGene qPCR primer pairs for LRIF1
- genomics-online: primer clones - Search results for available C1orf103 gene related products
Gene Expression Assay Products
No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LRIF1 Gene
Orthologs for LRIF1 Gene
This gene was present in the common ancestor of chordates.
| Organism | Taxonomy | Gene | Similarity | Type | Details |
|---|---|---|---|---|---|
| chimpanzee (Pan troglodytes) |
Mammalia | LRIF1 33 32 |
|
OneToOne | |
| dog (Canis familiaris) |
Mammalia | LRIF1 33 32 |
|
OneToOne | |
| cow (Bos Taurus) |
Mammalia | LRIF1 33 32 |
|
OneToOne | |
| mouse (Mus musculus) |
Mammalia | Lrif1 17 33 32 |
|
||
| rat (Rattus norvegicus) |
Mammalia | Lrif1 32 |
|
||
| oppossum (Monodelphis domestica) |
Mammalia | LRIF1 33 |
|
OneToOne | |
| platypus (Ornithorhynchus anatinus) |
Mammalia | LRIF1 33 |
|
OneToOne | |
| chicken (Gallus gallus) |
Aves | LRIF1 33 32 |
|
OneToOne | |
| lizard (Anolis carolinensis) |
Reptilia | LRIF1 33 |
|
OneToOne | |
| tropical clawed frog (Silurana tropicalis) |
Amphibia | LOC100492192 32 |
|
||
| zebrafish (Danio rerio) |
Actinopterygii | LRIF1 (1 of 2) 33 |
|
OneToMany | |
| LRIF1 (2 of 2) 33 |
|
OneToMany |
- Species where no ortholog for LRIF1 was found in the sources mined by GeneCards:
-
- A. gosspyii yeast (Ashbya gossypii)
- Actinobacteria (Mycobacterium tuberculosis)
- African clawed frog (Xenopus laevis)
- African malaria mosquito (Anopheles gambiae)
- Alicante grape (Vitis vinifera)
- alpha proteobacteria (Wolbachia pipientis)
- amoeba (Dictyostelium discoideum)
- Archea (Pyrococcus horikoshii)
- baker's yeast (Saccharomyces cerevisiae)
- barley (Hordeum vulgare)
- beta proteobacteria (Neisseria meningitidis)
- bread mold (Neurospora crassa)
- Chromalveolata (Phytophthora infestans)
- common water flea (Daphnia pulex)
- corn (Zea mays)
- E. coli (Escherichia coli)
- filamentous fungi (Aspergillus nidulans)
- Firmicute bacteria (Streptococcus pneumoniae)
- fission yeast (Schizosaccharomyces pombe)
- fruit fly (Drosophila melanogaster)
- green algae (Chlamydomonas reinhardtii)
- honey bee (Apis mellifera)
- K. lactis yeast (Kluyveromyces lactis)
- loblloly pine (Pinus taeda)
- malaria parasite (Plasmodium falciparum)
- medicago trunc (Medicago Truncatula)
- moss (Physcomitrella patens)
- orangutan (Pongo pygmaeus)
- pig (Sus scrofa)
- rainbow trout (Oncorhynchus mykiss)
- rice (Oryza sativa)
- rice blast fungus (Magnaporthe grisea)
- schistosome parasite (Schistosoma mansoni)
- sea anemone (Nematostella vectensis)
- sea squirt (Ciona intestinalis)
- sea squirt (Ciona savignyi)
- sea urchin (Strongylocentrotus purpuratus)
- sorghum (Sorghum bicolor)
- soybean (Glycine max)
- stem rust fungus (Puccinia graminis)
- sugarcane (Saccharum officinarum)
- thale cress (Arabidopsis thaliana)
- tomato (Lycopersicon esculentum)
- toxoplasmosis (Toxoplasma gondii)
- Trichoplax (Trichoplax adhaerens)
- wheat (Triticum aestivum)
- worm (Caenorhabditis elegans)
Evolution for LRIF1 Gene
- ENSEMBL:
- Gene Tree for LRIF1 (if available)
- TreeFam:
- Gene Tree for LRIF1 (if available)
- Aminode:
- Evolutionary constrained regions (ECRs) for LRIF1: view image
Paralogs for LRIF1 Gene
No data available for Paralogs for LRIF1 Gene
Variants for LRIF1 Gene
| SNP ID | Clin | Chr 01 pos | Variation | AA Info | Type |
|---|---|---|---|---|---|
| rs1000001229 | -- | 110,944,713(-) | A/C | genic_downstream_transcript_variant, intron_variant | |
| rs1000028461 | -- | 110,933,323(-) | T/C | genic_downstream_transcript_variant, intron_variant | |
| rs1000044035 | -- | 110,943,622(-) | G/A | genic_downstream_transcript_variant, intron_variant | |
| rs1000097644 | -- | 110,908,889(-) | C/A/T | genic_downstream_transcript_variant, intron_variant | |
| rs1000132727 | -- | 110,927,021(-) | T/C | genic_downstream_transcript_variant, intron_variant |
Residual Variation Intolerance Score:
19.3% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score:
6.77;
78.97% of all genes are more intolerant (likely to be disease-causing)
Additional Variant Information for LRIF1 Gene
- SNPedia medical, phenotypic, and genealogical associations of SNPs for
- LRIF1
SNP Genotyping and Copy Number Assay Products
No data available for Polymorphic Variants from UniProtKB/Swiss-Prot and Structural Variations from Database of Genomic Variants (DGV) for LRIF1 Gene
Disorders for LRIF1 Gene
Additional Disease Information for LRIF1
No disorders were found for LRIF1 Gene.
No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for LRIF1 Gene
Publications for LRIF1 Gene
- RIF-1, a novel nuclear receptor corepressor that associates with the nuclear matrix. (PMID: 17455211) Li HJ … Mendelsohn M (Journal of cellular biochemistry 2007) 2 3 4 56
- Human inactive X chromosome is compacted through a PRC2-independent SMCHD1-HBiX1 pathway. (PMID: 23542155) Nozawa RS … Obuse C (Nature structural & molecular biology 2013) 3 4 56
- The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 3 4 56
- Complete sequencing and characterization of 21,243 full-length human cDNAs. (PMID: 14702039) Ota T … Sugano S (Nature genetics 2004) 3 4 56
- The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). (PMID: 15489334) Gerhard DS … MGC Project Team (Genome research 2004) 3 4 56
ExternalLinks
Products for LRIF1 Gene
- Custom Antibody Services
- Browse OriGene ELISA Kits
- Custom Assay Services
- Search Origene for Purified Proteins, MassSpec and Protein Over-expression Lysates for LRIF1
- Origene Custom Protein Services for LRIF1
- Origene sirna, shrna, and RNAi products in human, mouse, rat for LRIF1
- Browse OriGene Inhibitory RNA Products For LRIF1
- OriGene qPCR primer pairs for LRIF1
- OriGene CRISPR knockouts for LRIF1
- MG213437
- MG214341
- MG214420
- MR213437
- MR213437L3
- MR213437L3V
- MR213437L4
- MR213437L4V
- MR214341
- MR214341L3
- MR214341L3V
- MR214341L4
- MR214341L4V
- MR214420
- MR214420L3
- MR214420L3V
- MR214420L4
- MR214420L4V
- MR228702
- RC203729
- RC203729L3
- RC203729L3V
- RC203729L4
- RC203729L4V
- RC213259
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- RC213259L3V
- RC213259L4
- RC213259L4V
- RG203729
- RG213259
- RR208879
- RR208879L3
- RR208879L3V
- RR208879L4
- RR208879L4V
- Custom cloning services - gene synthesis, subcloning, mutagenesis, variant library, vector shuttling
- Browse OriGene miRNA Products For LRIF1
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- Invitrogen Antibodies for LRIF1 (AFLGC-LRIF1)
- antibodies-online: Show 4 available C1orf103 Antibodies ranked by validation data
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- antibodies-online: Search results for available C1orf103 related products ranked by validation data
- antibodies-online: Show 4 available C1orf103 Proteins ranked by validation data
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- Horizon Cell Lines for LRIF1
- genomics-online: cdna clones - Search results for available C1orf103 gene related products
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- Search GeneCopoeia for CRISPR/Cas9 clones, lentivirus and AAV products for LRIF1
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- Search GeneCopoeia for miRNA 3'UTR Target clone products for LRIF1
- Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LRIF1
Sources for LRIF1 Gene
- (1) GeneCards
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- (3) NCBI Entrez Gene
- (4) UniProtKB/Swiss-Prot
- (5) Ensembl
- (6) OMIM
- (7) GeneLoc
- (8) Gene Wiki
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- (13) UniProtKB/TrEMBL
- (14) InterPro
- (15) ProtoNet
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- (24) PharmGKB
- (25) DrugBank
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- (27) AceView
- (28) ASD
- (29) ECgene
- (30) CGAP SAGE
- (31) SOURCE
- (32) HomoloGene
- (33) PanEnsembl
- (34) euGenes
- (35) SGD
- (36) FlyBase
- (37) WormBase
- (38) Pseudogene
- (39) DGV
- (40) dbSNP
- (41) GenAtlas
- (42) HGMD
- (43) GAD
- (44) BGMUT
- (45) HuGE
- (46) Atlas
- (47) GenBank
- (48) H-invDB
- (49) HORDE
- (50) HUGE
- (51) IMGT
- (52) Leiden
- (53) miRBase
- (54) DME
- (55) OriGene
- (56) PubMed
- (57) R&D Systems
- (58) TGDB
- (59) Tocris
- (60) Abcam
- (61) Novus Biologicals
- (62) ProSpec
- (63) Sino Biological
- (64) GenScript
- (65) Qiagen
- (66) OCA
- (67) Proteopedia
- (68) MOPED
- (69) neXtProt
- (70) Reactome
- (71) GeneGo (Thomson Reuters)
- (72) DISEASES
- (73) SIMAP
- (74) GenomeRNAi
- (75) LifeMap
- (76) miRTarBase
- (77) MalaCards
- (78) Invitrogen
- (79) BitterDB
- (80) ESI-BIO
- (81) RefSeq
- (82) BioSystems
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- (84) IUPHAR
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- (86) Illumina
- (87) COMPARTMENTS
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- (89) PaxDb
- (90) ApexBio
- (91) Addgene
- (92) antibodies-online
- (93) CYP
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- (95) TreeFam
- (96) PathCards
- (97) GeneReviews
- (98) GeneTex
- (99) Taconic Biosciences
- (100) GTEx
- (101) ProteomicsDB
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- (103) DGIdb
- (104) ClinicalTrials
- (105) RVIS
- (106) SIGNOR
- (107) diseasecard
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- (138) abm
- (139) Human Protein Atlas
- (140) GWAS Catalog
- (141) Monarch Initiative
- (142) DataMed
- (143) HumanCyc
- (144) genomics-online
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- (152) RNACentral
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- (156) DiseaseEnhancer
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- (164) Synthego
- (165) Bio Basic
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- (168) LncBase
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- (170) LNCipedia
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