Aliases for LRCH2 Gene
External Ids for LRCH2 Gene
Previous GeneCards Identifiers for LRCH2 Gene
This gene encodes a member of the leucine-rich repeat and calponin homology domain-containing protein family. These family members contain multiple N-terminal leucine-rich repeats, in addition to a C-terminal calponin homology domain, a type of domain that mediates interactions with actin filaments. These proteins are conserved across animal species, and studies of a similar Drosophila protein indicate a function as a cytoskeletal scaffolding protein. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Sep 2011]
GeneCards Summary for LRCH2 Gene
LRCH2 (Leucine Rich Repeats And Calponin Homology Domain Containing 2) is a Protein Coding gene. Diseases associated with LRCH2 include Hermansky-Pudlak Syndrome 3 and Separation Anxiety Disorder. An important paralog of this gene is LRCH1.
UniProtKB/Swiss-Prot Summary for LRCH2 Gene
May play a role in the organization of the cytoskeleton.