This gene encodes a member of a subfamily of LIM domain proteins that are characterized by an N-terminal proline-rich region and three C-terminal LIM domains. The encoded protein localizes to the cell periphery in focal adhesions and may be involved in cell-cell adhesion and cell motility. This protein also shuttles through the nucleus and may function as a transcriptional co-a... See more...

Aliases for LPP Gene

Aliases for LPP Gene

  • LIM Domain Containing Preferred Translocation Partner In Lipoma 2 3 5
  • LIM Domain-Containing Preferred Translocation Partner In Lipoma 2 4
  • Lipoma-Preferred Partner 3 4
  • Lipoma Preferred Partner Gene 2
  • Lipoma Preferred Partner 3
  • LIM Protein 3

External Ids for LPP Gene

Previous GeneCards Identifiers for LPP Gene

  • GC03P184748
  • GC03P189132
  • GC03P189272
  • GC03P189191
  • GC03P189251
  • GC03P189413
  • GC03P187871
  • GC03P185276

Summaries for LPP Gene

Entrez Gene Summary for LPP Gene

  • This gene encodes a member of a subfamily of LIM domain proteins that are characterized by an N-terminal proline-rich region and three C-terminal LIM domains. The encoded protein localizes to the cell periphery in focal adhesions and may be involved in cell-cell adhesion and cell motility. This protein also shuttles through the nucleus and may function as a transcriptional co-activator. This gene is located at the junction of certain disease-related chromosomal translocations, which result in the expression of chimeric proteins that may promote tumor growth. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]

GeneCards Summary for LPP Gene

LPP (LIM Domain Containing Preferred Translocation Partner In Lipoma) is a Protein Coding gene. Diseases associated with LPP include Leukemia, Acute Myeloid and Acute Monoblastic Leukemia. Among its related pathways are Stabilization and expansion of the E-cadherin adherens junction and Cytoskeletal Signaling. An important paralog of this gene is FBLIM1.

UniProtKB/Swiss-Prot Summary for LPP Gene

  • May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion sites. Also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus.

Gene Wiki entry for LPP Gene

Additional gene information for LPP Gene

No data available for CIViC Summary , Tocris Summary , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for LPP Gene

Genomics for LPP Gene

GeneHancer (GH) Regulatory Elements for LPP Gene

Promoters and enhancers for LPP Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH03J188152 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE CraniofacialAtlas dbSUPER 500.7 +3.9 3908 8.1 ZNF217 EP300 TCF12 POLR2G USF1 NCOR1 PHF8 TEAD4 ZFX ZIC2 LPP LPP-AS2 ENSG00000228804 JX046913 RF00017-4204
GH03J188330 Promoter/Enhancer 0.7 EPDnew Ensembl 510.1 +178.1 178058 2.4 USF1 REST RXRA LPP lnc-BCL6-9 hsa-miR-5095-361
GH03J187735 Promoter/Enhancer 2.7 EPDnew FANTOM5 Ensembl ENCODE CraniofacialAtlas dbSUPER 11.7 -410.3 -410333 13 EP300 FOXK2 HNRNPK ZBTB40 ZNF217 CTCF ZSCAN5C NRF1 TCF12 MYC BCL6 ENSG00000285938 ENSG00000228804 RFC4 SNORA4 SNORA63B SNORA81 LPP ST6GAL1 RTP4
GH03J188228 Enhancer 1.2 FANTOM5 Ensembl ENCODE dbSUPER 16.5 +78.2 78158 3.8 TCF7 SKI TBX3 FOXA2 RBM22 NR3C1 FOXP1 SMAD4 FOS ZNF189 LPP RF00994-713 piR-38580-216
GH03J188292 Enhancer 1.4 FANTOM5 ENCODE dbSUPER 12.1 +143.7 143660 6.9 EP300 FOXK2 ZSCAN5C TCF12 POLR2G NCOR1 JUND FOS ZNF10 REST LPP hsa-miR-5095-361 lnc-BCL6-9
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around LPP on UCSC Golden Path with GeneCards custom track

Cistromic (ChIP-Seq) regulation report from SPP (The Signaling Pathways Project) for LPP

Top Transcription factor binding sites by QIAGEN in the LPP gene promoter:
  • IRF-7A
  • Nkx2-5
  • Olf-1
  • p53
  • TBP
  • ZID

Genomic Locations for LPP Gene

Genomic Locations for LPP Gene
chr3:188,152,143-188,890,671
(GRCh38/hg38)
Size:
738,529 bases
Orientation:
Plus strand
chr3:187,871,072-188,608,460
(GRCh37/hg19)
Size:
737,389 bases
Orientation:
Plus strand

Genomic View for LPP Gene

Genes around LPP on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LPP Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LPP Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LPP Gene

Proteins for LPP Gene

  • Protein details for LPP Gene (UniProtKB/Swiss-Prot)

    Protein Symbol:
    Q93052-LPP_HUMAN
    Recommended name:
    Lipoma-preferred partner
    Protein Accession:
    Q93052
    Secondary Accessions:
    • A1L4L6
    • D3DNV6
    • Q8NFX5

    Protein attributes for LPP Gene

    Size:
    612 amino acids
    Molecular mass:
    65746 Da
    Quaternary structure:
    • Interacts with VASP, with PDZ domains of SCRIB and with ACTN1/alpha-actinin.

neXtProt entry for LPP Gene

Post-translational modifications for LPP Gene

  • Modification sites at PhosphoSitePlus
  • Modification sites at neXtProt

No data available for DME Specific Peptides for LPP Gene

Domains & Families for LPP Gene

Gene Families for LPP Gene

HGNC:
Human Protein Atlas (HPA):
  • Cancer-related genes
  • Disease related genes
  • Plasma proteins
  • Predicted intracellular proteins

Protein Domains for LPP Gene

Blocks:
  • Zn-binding protein, LIM
InterPro:
ProtoNet:

Suggested Antigen Peptide Sequences for LPP Gene

GenScript: Design optimal peptide antigens:
  • LPP protein (B7ZLW0_HUMAN)
  • LIM domain-containing preferred translocation partner in lipoma (LPP_HUMAN)

Graphical View of Domain Structure for InterPro Entry

Q93052

UniProtKB/Swiss-Prot:

LPP_HUMAN :
  • Belongs to the zyxin/ajuba family.
Family:
  • Belongs to the zyxin/ajuba family.
genes like me logo Genes that share domains with LPP: view

Function for LPP Gene

Molecular function for LPP Gene

UniProtKB/Swiss-Prot Function:
May play a structural role at sites of cell adhesion in maintaining cell shape and motility. In addition to these structural functions, it may also be implicated in signaling events and activation of gene transcription. May be involved in signal transduction from cell adhesion sites to the nucleus allowing successful integration of signals arising from soluble factors and cell-cell adhesion sites. Also suggested to serve as a scaffold protein upon which distinct protein complexes are assembled in the cytoplasm and in the nucleus.
GENATLAS Biochemistry:
lipoma preferred fusion partner of HMGIC,LIM protein gene family,group 3

Phenotypes From GWAS Catalog for LPP Gene

Gene Ontology (GO) - Molecular Function for LPP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0005515 protein binding IPI 15649318
GO:0046872 metal ion binding IEA --
genes like me logo Genes that share ontologies with LPP: view
genes like me logo Genes that share phenotypes with LPP: view

Human Phenotype Ontology for LPP Gene

HPO Id HPO Name Alternative Ids Definition Synonyms

Animal Models for LPP Gene

MGI Knock Outs for LPP:
  • Lpp Lpp<tm1Wjmv>

Animal Model Products

CRISPR Products

miRNA for LPP Gene

miRTarBase miRNAs that target LPP

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LPP

Clone Products

No data available for Enzyme Numbers (IUBMB) , Transcription Factor Targets and HOMER Transcription for LPP Gene

Localization for LPP Gene

Subcellular locations from UniProtKB/Swiss-Prot for LPP Gene

Nucleus. Cytoplasm. Cell junction. Cell membrane. Note=Found in the nucleus, in the cytoplasm and at cell adhesion sites. Shuttles between the cytoplasm and the nucleus. It has been found in sites of cell adhesion such as cell-to-cell contact and focal adhesion which are membrane attachment sites of cells to the extracellular matrix. Mainly nuclear when fused with HMGA2/HMGIC and KMT2A/MLL1.

Subcellular locations from

COMPARTMENTS
Extracellular space Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi Apparatus Nucleus Mitochondrion 0 1 2 3 4 5 Confidence
COMPARTMENTS Subcellular localization image for LPP gene
Compartment Confidence
plasma membrane 5
nucleus 5
cytosol 5
cytoskeleton 4
extracellular 2
mitochondrion 1
peroxisome 1
endoplasmic reticulum 1
endosome 1
lysosome 1
golgi apparatus 1

Subcellular locations from the

Human Protein Atlas (HPA)
  • Cytosol (4)
  • Focal adhesion sites (4)
See all subcellular structures

Gene Ontology (GO) - Cellular Components for LPP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0001725 stress fiber IBA 21873635
GO:0005634 nucleus IEA --
GO:0005737 cytoplasm IEA --
GO:0005829 cytosol IDA --
GO:0005886 plasma membrane IEA --
genes like me logo Genes that share ontologies with LPP: view

Pathways & Interactions for LPP Gene

genes like me logo Genes that share pathways with LPP: view

Pathways by source for LPP Gene

1 Cell Signaling Technology pathway for LPP Gene

SIGNOR curated interactions for LPP Gene

Is activated by:

Gene Ontology (GO) - Biological Process for LPP Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0007155 cell adhesion IEA --
GO:0008150 biological_process ND --
GO:0098609 cell-cell adhesion IBA 21873635
genes like me logo Genes that share ontologies with LPP: view

Drugs & Compounds for LPP Gene

(5) Drugs for LPP Gene - From: ClinicalTrials and Novoseek

Name Status Disease Links Group Role Mechanism of Action Clinical Trials
Ethanol Approved Pharma 3220
Anti-Infective Agents Pharma 26962
Anti-Infective Agents, Local Pharma 2666
Central Nervous System Depressants Pharma 18395

(1) Additional Compounds for LPP Gene - From: Novoseek

Name Synonyms Role CAS Number PubChem IDs PubMed IDs
genes like me logo Genes that share compounds with LPP: view

Transcripts for LPP Gene

mRNA/cDNA for LPP Gene

14 REFSEQ mRNAs :
18 NCBI additional mRNA sequence :
22 Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LPP

Clone Products

Alternative Splicing Database (ASD) splice patterns (SP) for LPP Gene

No ASD Table

Relevant External Links for LPP Gene

GeneLoc Exon Structure for
LPP

Expression for LPP Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and SAGE for LPP Gene

mRNA expression in embryonic tissues and stem cells from LifeMap Discovery

mRNA differential expression in normal tissues according to GTEx for LPP Gene

This gene is overexpressed in Artery - Tibial (x6.6) and Esophagus - Muscularis (x4.9).

Protein differential expression in normal tissues from HIPED for LPP Gene

This gene is overexpressed in Uterus (15.0), Urinary Bladder (11.7), Prostate (8.2), Rectum (7.0), and Cardia (6.8).

Integrated Proteomics: protein expression in normal tissues and cell lines from ProteomicsDB, MaxQB, and MOPED for LPP Gene



Protein tissue co-expression partners for LPP Gene

- Elite partner

Transcriptomic regulation report from SPP (The Signaling Pathways Project) for LPP

SOURCE GeneReport for Unigene cluster for LPP Gene:

Hs.720220

mRNA Expression by UniProt/SwissProt for LPP Gene:

Q93052-LPP_HUMAN
Tissue specificity: Expressed in a wide variety of tissues but no or very low expression in brain and peripheral leukocytes.

Evidence on tissue expression from TISSUES for LPP Gene

  • Intestine(4.6)
  • Liver(4.3)
  • Nervous system(4.1)
  • Skin(3.1)
  • Lung(2.5)
  • Heart(2.3)
  • Muscle(2.2)
  • Blood(2.1)
  • Gall bladder(2)

Phenotype-based relationships between genes and organs from Gene ORGANizer for LPP Gene

Germ Layers:
  • mesoderm
Systems:
  • immune
  • lymphatic
Regions:
General:
  • blood
  • bone marrow
  • white blood cell
genes like me logo Genes that share expression patterns with LPP: view

Orthologs for LPP Gene

This gene was present in the common ancestor of animals.

Orthologs for LPP Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LPP 31 30
  • 99.51 (n)
OneToOne
cow
(Bos Taurus)
Mammalia LPP 31 30
  • 89.54 (n)
OneToOne
dog
(Canis familiaris)
Mammalia LPP 31 30
  • 88.94 (n)
OneToOne
mouse
(Mus musculus)
Mammalia Lpp 17 31 30
  • 85.73 (n)
rat
(Rattus norvegicus)
Mammalia Lpp 30
  • 84.05 (n)
platypus
(Ornithorhynchus anatinus)
Mammalia LPP 31
  • 82 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia LPP 31
  • 80 (a)
OneToOne
chicken
(Gallus gallus)
Aves LPP 31 30
  • 74.23 (n)
OneToOne
lizard
(Anolis carolinensis)
Reptilia LPP 31
  • 73 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia lpp 30
  • 74.82 (n)
zebrafish
(Danio rerio)
Actinopterygii lpp 31 30
  • 68.91 (n)
OneToOne
zgc56152 30
fruit fly
(Drosophila melanogaster)
Insecta Zyx102EF 32
  • 62 (a)
Zyx 31
  • 30 (a)
OneToMany
worm
(Caenorhabditis elegans)
Secernentea zyx-1 32
  • 52 (a)
Species where no ortholog for LPP was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)

Evolution for LPP Gene

ENSEMBL:
Gene Tree for LPP (if available)
TreeFam:
Gene Tree for LPP (if available)
Aminode:
Evolutionary constrained regions (ECRs) for LPP: view image

Paralogs for LPP Gene

Paralogs for LPP Gene

(6) SIMAP similar genes for LPP Gene using alignment to 12 proteins:

  • LPP_HUMAN
  • B7ZLW0_HUMAN
  • C9J1K7_HUMAN
  • C9J2R5_HUMAN
  • C9J3U9_HUMAN
  • C9J4E3_HUMAN
  • C9J5C8_HUMAN
  • C9JE51_HUMAN
  • C9JIY7_HUMAN
  • C9JT42_HUMAN
  • C9JUT4_HUMAN
  • C9JXK9_HUMAN
genes like me logo Genes that share paralogs with LPP: view

Variants for LPP Gene

Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP for LPP Gene

SNP ID Clinical significance and condition Chr 03 pos Variation AA Info Type
730114 Likely Benign: not provided 188,708,315(+) C/T MISSENSE_VARIANT
756191 Likely Benign: not provided 188,609,826(+) G/A NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT,INTRON_VARIANT
774441 Benign: not provided 188,760,267(+) C/T NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT
775935 Benign: not provided 188,609,319(+) C/T NON_CODING_TRANSCRIPT_VARIANT,SYNONYMOUS_VARIANT
777969 Benign: not provided 188,708,296(+) G/A SYNONYMOUS_VARIANT

Additional dbSNP identifiers (rs#s) for LPP Gene

Structural Variations from Database of Genomic Variants (DGV) for LPP Gene

Variant ID Type Subtype PubMed ID
dgv1436e212 CNV loss 25503493
dgv1437e212 CNV loss 25503493
dgv2655n106 CNV deletion 24896259
dgv5006n100 CNV loss 25217958
dgv8778n54 CNV loss 21841781
dgv900e199 CNV deletion 23128226
dgv964e214 CNV gain 21293372
esv1535519 CNV insertion 17803354
esv1727014 CNV deletion 17803354
esv2313176 CNV deletion 18987734
esv2471009 CNV deletion 19546169
esv2506913 CNV deletion 19546169
esv2541501 CNV deletion 19546169
esv2664419 CNV deletion 23128226
esv2669680 CNV deletion 23128226
esv2726356 CNV deletion 23290073
esv2726357 CNV deletion 23290073
esv2751987 CNV gain 17911159
esv2762370 CNV loss 21179565
esv2763328 CNV loss 21179565
esv2763329 CNV gain 21179565
esv33400 CNV gain 17666407
esv34193 CNV loss 18971310
esv3563060 CNV deletion 23714750
esv3569171 CNV loss 25503493
esv3599026 CNV loss 21293372
esv3599028 CNV gain 21293372
esv3599029 CNV gain 21293372
esv3599030 CNV loss 21293372
esv3599032 CNV loss 21293372
esv3599033 CNV loss 21293372
esv3599037 CNV loss 21293372
esv3599039 CNV loss 21293372
esv7339 CNV loss 19470904
nsv1003486 CNV gain 25217958
nsv1010485 CNV loss 25217958
nsv1073271 CNV deletion 25765185
nsv1074648 CNV deletion 25765185
nsv1123722 CNV deletion 24896259
nsv1128010 CNV deletion 24896259
nsv1128011 CNV deletion 24896259
nsv1131747 CNV deletion 24896259
nsv1136791 CNV deletion 24896259
nsv1136792 CNV deletion 24896259
nsv1153167 CNV deletion 26484159
nsv1161013 CNV duplication 26073780
nsv236225 CNV deletion 16902084
nsv4161 CNV insertion 18451855
nsv4162 CNV insertion 18451855
nsv461046 CNV loss 19166990
nsv461047 CNV loss 19166990
nsv513100 CNV loss 21212237
nsv592757 CNV loss 21841781
nsv592758 CNV loss 21841781
nsv592759 CNV loss 21841781
nsv592760 CNV loss 21841781
nsv819096 CNV loss 19587683
nsv822370 CNV loss 20364138
nsv955538 CNV deletion 24416366
nsv955601 CNV deletion 24416366

Variation tolerance for LPP Gene

Residual Variation Intolerance Score: 73.4% of all genes are more intolerant (likely to be disease-causing)
Gene Damage Index Score: 8.86; 87.01% of all genes are more intolerant (likely to be disease-causing)

Additional Variant Information for LPP Gene

Human Gene Mutation Database (HGMD)
LPP
SNPedia medical, phenotypic, and genealogical associations of SNPs for
LPP

SNP Genotyping and Copy Number Assay Products

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot for LPP Gene

Disorders for LPP Gene

MalaCards: The human disease database

(24) MalaCards diseases for LPP Gene - From: OMIM, GTR, DISEASES, Novoseek, and GeneCards

Disorder Aliases PubMed IDs
leukemia, acute myeloid
  • aml
acute monoblastic leukemia
  • acute monocytic leukemia
infiltrating lipoma
  • intramuscular lipoma
lipomatosis, multiple
  • lipomatosis, familial multiple; fml
vacterl association
  • vater syndrome
- elite association - COSMIC cancer census association via MalaCards
Search LPP in MalaCards View complete list of genes associated with diseases

UniProtKB/Swiss-Prot

LPP_HUMAN
  • Note=A chromosomal aberration involving LPP is associated with a subclass of benign mesenchymal tumors known as lipomas. Translocation t(3;12)(q27-q28;q13-q15) with HMGA2 is shown in lipomas.
  • Note=A chromosomal aberration involving LPP is associated with pulmonary chondroid hamartomas. Translocation t(3;12)(q27-q28;q14-q15) with HMGA2 is detected in pulmonary chondroid hamartomas.
  • Note=A chromosomal aberration involving LPP is associated with parosteal lipomas. Translocation t(3;12)(q28;q14) with HMGA2 is also shown in one parosteal lipoma.
  • Note=A chromosomal aberration involving LPP is associated with acute monoblastic leukemia. Translocation t(3;11)(q28;q23) with KMT2A/MLL1 is associated with acute monoblastic leukemia.

Additional Disease Information for LPP

Genetic Association Database
(GAD)
Human Genome Epidemiology Navigator
(HuGE)
ATLAS of Genetics and Cytogenetics in Oncology and Haematology
genes like me logo Genes that share disorders with LPP: view

No data available for Genatlas for LPP Gene

Publications for LPP Gene

  1. The focal adhesion and nuclear targeting capacity of the LIM-containing lipoma-preferred partner (LPP) protein. (PMID: 12441356) Petit MM … Van de Ven WJ (The Journal of biological chemistry 2003) 3 4 23 54
  2. LPP, an actin cytoskeleton protein related to zyxin, harbors a nuclear export signal and transcriptional activation capacity. (PMID: 10637295) Petit MM … Friederich E (Molecular biology of the cell 2000) 3 4 23 54
  3. Expression of reciprocal fusion transcripts of the HMGIC and LPP genes in parosteal lipoma. (PMID: 9772904) Petit MM … Van de Ven WJ (Cancer genetics and cytogenetics 1998) 3 4 23 54
  4. LPP, the preferred fusion partner gene of HMGIC in lipomas, is a novel member of the LIM protein gene family. (PMID: 8812423) Petit MM … Van de Ven WJ (Genomics 1996) 2 3 4 54
  5. A genome-wide association study of plasma total IgE concentrations in the Framingham Heart Study. (PMID: 22075330) Granada M … O'Connor GT (The Journal of allergy and clinical immunology 2012) 3 41 54

Products for LPP Gene

Sources for LPP Gene