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LONRF2 (LON Peptidase N-Terminal Domain And Ring Finger 2) is a Protein Coding gene. Diseases associated with LONRF2 include Pediatric Germ Cell Cancer. Gene Ontology (GO) annotations related to this gene include ATP-dependent peptidase activity. An important paralog of this gene is LONRF3.
GO ID | Qualified GO term | Evidence | PubMed IDs |
---|---|---|---|
GO:0005515 | protein binding | IPI | 32814053 |
GO:0046872 | metal ion binding | IEA | -- |
This gene was present in the common ancestor of animals.
Organism | Taxonomy | Gene | Similarity | Type | Details |
---|---|---|---|---|---|
Chimpanzee (Pan troglodytes) |
Mammalia | LONRF2 30 31 |
|
OneToOne | |
Dog (Canis familiaris) |
Mammalia | LONRF2 30 31 |
|
OneToOne | |
Rat (Rattus norvegicus) |
Mammalia | Lonrf2 30 |
|
||
Mouse (Mus musculus) |
Mammalia | Lonrf2 30 17 31 |
|
OneToOne | |
Cow (Bos Taurus) |
Mammalia | LONRF2 30 31 |
|
OneToOne | |
Platypus (Ornithorhynchus anatinus) |
Mammalia | LONRF2 31 |
|
OneToOne | |
Oppossum (Monodelphis domestica) |
Mammalia | LONRF2 31 |
|
OneToOne | |
Chicken (Gallus gallus) |
Aves | LONRF2 30 31 |
|
OneToOne | |
Lizard (Anolis carolinensis) |
Reptilia | LONRF2 31 |
|
OneToOne | |
Tropical Clawed Frog (Silurana tropicalis) |
Amphibia | lonrf2 30 |
|
||
Zebrafish (Danio rerio) |
Actinopterygii | si:ch1073-440b2.1 30 |
|
||
LONRF2 31 |
|
OneToOne | |||
Fruit Fly (Drosophila melanogaster) |
Insecta | CG32369 31 |
|
OneToMany | |
Sea Squirt (Ciona savignyi) |
Ascidiacea | -- 31 |
|
OneToMany |
SNP ID | Clinical significance and condition | Chr 02 pos | Variation | AA Info | Type |
---|---|---|---|---|---|
rs116227203 | Benign: not provided | 100,295,518(-) |
C/T NM_198461.4(LONRF2):c.1512G>A (p.Leu504=) |
SYNONYMOUS | |
rs4851287 | -. - |
p.Leu183Prop.Leu426Pro |
|||
rs773205136 | A colorectal cancer sample |
p.Arg562Trp |
Variant ID | Type | Subtype | PubMed ID |
---|---|---|---|
dgv1157e212 | CNV | loss | 25503493 |
dgv609e201 | CNV | deletion | 23290073 |
esv2053654 | CNV | deletion | 18987734 |
esv2675961 | CNV | deletion | 23128226 |
esv2720436 | CNV | deletion | 23290073 |
esv3583986 | CNV | loss | 25503493 |
esv3591751 | CNV | loss | 21293372 |
esv3591752 | CNV | loss | 21293372 |
esv7741 | CNV | gain | 19470904 |
nsv1072959 | CNV | deletion | 25765185 |
nsv1123362 | CNV | deletion | 24896259 |
nsv1136389 | CNV | deletion | 24896259 |
nsv582531 | CNV | gain | 21841781 |
nsv834311 | CNV | gain+loss | 17160897 |
nsv953495 | CNV | deletion | 24416366 |
Disorder | Aliases | PubMed IDs |
---|---|---|
pediatric germ cell cancer |
|
|