Free for academic non-profit institutions. Other users need a Commercial license

Aliases for LOC400499 Gene

Aliases for LOC400499 Gene

  • Vitellogenin 3 5
  • Putative Uncharacterized Protein LOC400499 3
  • Uncharacterized Protein 13
  • AC099489.1 5

External Ids for LOC400499 Gene

Previous GeneCards Identifiers for LOC400499 Gene

  • GC16M011502
  • GC16M011397
  • GC16M011490

Summaries for LOC400499 Gene

GeneCards Summary for LOC400499 Gene

LOC400499 (Vitellogenin) is a Protein Coding gene. Gene Ontology (GO) annotations related to this gene include lipid transporter activity.

Additional gene information for LOC400499 Gene

No data available for Entrez Gene Summary , CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LOC400499 Gene

Genomics for LOC400499 Gene

GeneHancer (GH) Regulatory Elements for LOC400499 Gene

Promoters and enhancers for LOC400499 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH16J011527 Promoter 0.5 Ensembl 600.7 +0.1 144 0.6 LOC400499 LITAF GC16M011515 GC16M011514
GH16J011639 Promoter/Enhancer 2.3 VISTA FANTOM5 Ensembl ENCODE dbSUPER 12.1 -113.4 -113413 3.3 MTA3 ZFX ELF3 CTCF CEBPG ZSCAN21 NCOA3 IKZF1 BACH1 MCM2 ENSG00000263307 HNRNPCP4 LITAF ENSG00000261560 COX6CP1 ZC3H7A ENSG00000261216 TXNDC11 NPIPB2 SOCS1
GH16J011635 Promoter/Enhancer 1.4 Ensembl ENCODE dbSUPER 12.1 -109.0 -108955 1.7 SP1 POLR2A CREB1 REST E4F1 KLF4 USF1 MNT ZNF217 ELF1 LITAF LOC400499 HNRNPCP4 ENSG00000263307 ENSG00000261560 SNN
GH16J011493 Enhancer 1 ENCODE 15.9 +31.1 31124 5.8 SP1 CBFA2T2 ZNF148 ZNF384 NFIB AHR SP7 ELF1 PRDM1 EGR1 HNRNPCP4 LOC400499 ENSG00000261560 ENSG00000263307 GC16M011514 GC16M011515 GC16P011478
GH16J011638 Promoter/Enhancer 1.1 Ensembl dbSUPER 12.1 -111.6 -111556 0.4 IKZF1 CTBP1 MCM3 FOXA2 TBX3 CREB1 ZNF366 PLRG1 ATF2 FOXK2 ENSG00000263307 ENSG00000261560 HNRNPCP4 COX6CP1 LOC400499 ZC3H7A ENSG00000261216 NUBP1 SNN LITAF
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around LOC400499 on UCSC Golden Path with GeneCards custom track

Top Transcription factor binding sites by QIAGEN in the LOC400499 gene promoter:
  • AML1a
  • GR
  • GR-alpha
  • GR-beta
  • HSF2
  • p53
  • Pax-5
  • Pax-6
  • Sox9
  • SRY

Genomic Locations for LOC400499 Gene

Genomic Locations for LOC400499 Gene
chr16:11,359,845-11,527,245
(GRCh38/hg38)
Size:
167,401 bases
Orientation:
Minus strand
chr16:11,453,702-11,617,444
(GRCh37/hg19)
Size:
163,743 bases
Orientation:
Minus strand

Genomic View for LOC400499 Gene

Genes around LOC400499 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LOC400499 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LOC400499 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LOC400499 Gene

Proteins for LOC400499 Gene

  • Protein details for LOC400499 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    M0R1J3-M0R1J3_HUMAN
    Recommended name:
    Uncharacterized protein
    Protein Accession:
    M0R1J3

    Protein attributes for LOC400499 Gene

    Size:
    79 amino acids
    Molecular mass:
    9097 Da
    Quaternary structure:
    No Data Available
  • Protein details for LOC400499 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    M0QZD8-M0QZD8_HUMAN
    Recommended name:
    Uncharacterized protein
    Protein Accession:
    M0QZD8

    Protein attributes for LOC400499 Gene

    Size:
    3266 amino acids
    Molecular mass:
    357809 Da
    Quaternary structure:
    No Data Available
  • Protein details for LOC400499 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    M0R2I5-M0R2I5_HUMAN
    Recommended name:
    Uncharacterized protein
    Protein Accession:
    M0R2I5

    Protein attributes for LOC400499 Gene

    Size:
    46 amino acids
    Molecular mass:
    4948 Da
    Quaternary structure:
    No Data Available
  • Protein details for LOC400499 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    M0R2X1-M0R2X1_HUMAN
    Recommended name:
    Uncharacterized protein
    Protein Accession:
    M0R2X1

    Protein attributes for LOC400499 Gene

    Size:
    455 amino acids
    Molecular mass:
    49139 Da
    Quaternary structure:
    No Data Available

neXtProt entry for LOC400499 Gene

Post-translational modifications for LOC400499 Gene

No Post-translational modifications

No data available for DME Specific Peptides for LOC400499 Gene

Domains & Families for LOC400499 Gene

Graphical View of Domain Structure for InterPro Entry

genes like me logo Genes that share domains with LOC400499: view

No data available for Gene Families , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for LOC400499 Gene

Function for LOC400499 Gene

Phenotypes From GWAS Catalog for LOC400499 Gene

Phenotypes for LOC400499 Gene

genes like me logo Genes that share phenotypes with LOC400499: view

Animal Model Products

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LOC400499

No data available for Molecular function , Enzyme Numbers (IUBMB) , Gene Ontology (GO) - Molecular Function , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LOC400499 Gene

Localization for LOC400499 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LOC400499 Gene

Pathways & Interactions for LOC400499 Gene

PathCards logo

SuperPathways for LOC400499 Gene

No Data Available

Interacting Proteins for LOC400499 Gene

Gene Ontology (GO) - Biological Process for LOC400499 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0006869 lipid transport IEA --
GO:0032355 response to estradiol IBA --
GO:0071391 cellular response to estrogen stimulus IBA --
genes like me logo Genes that share ontologies with LOC400499: view

No data available for Pathways by source and SIGNOR curated interactions for LOC400499 Gene

Drugs & Compounds for LOC400499 Gene

No Compound Related Data Available

Transcripts for LOC400499 Gene

mRNA/cDNA for LOC400499 Gene

(1) Additional mRNA sequences :
(5) Selected AceView cDNA sequences:
(8) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Unigene Clusters for LOC400499 Gene

Uncharacterized LOC400499:
Representative Sequences:

CRISPR Products

Inhibitory RNA Products

  • Search GeneCopoeia for shRNA, lentivirus and/or AAV clone products for LOC400499

Alternative Splicing Database (ASD) splice patterns (SP) for LOC400499 Gene

No ASD Table

Relevant External Links for LOC400499 Gene

GeneLoc Exon Structure for
LOC400499

Expression for LOC400499 Gene

mRNA expression in normal human tissues from GTEx, Illumina, BioGPS, and CGAP SAGE for LOC400499 Gene

Protein differential expression in normal tissues from HIPED for LOC400499 Gene

This gene is overexpressed in Breast (67.4).

Integrated Proteomics: protein expression in normal tissues and cell lines from MOPED for LOC400499 Gene



Protein tissue co-expression partners for LOC400499 Gene

- Elite partner

SOURCE GeneReport for Unigene cluster for LOC400499 Gene:

Hs.459937
genes like me logo Genes that share expression patterns with LOC400499: view

No data available for mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LOC400499 Gene

Orthologs for LOC400499 Gene

This gene was present in the common ancestor of chordates.

Orthologs for LOC400499 Gene

Organism Taxonomy Gene Similarity Type Details
chimpanzee
(Pan troglodytes)
Mammalia LOC738641 34
  • 98.17 (n)
-- 35
  • 96 (a)
OneToOne
cow
(Bos Taurus)
Mammalia LOC616782 34
  • 81 (n)
-- 35
  • 72 (a)
OneToOne
dog
(Canis familiaris)
Mammalia LOC102153019 34
  • 78.36 (n)
-- 35
  • 72 (a)
OneToOne
platypus
(Ornithorhynchus anatinus)
Mammalia -- 35
  • 51 (a)
OneToOne
oppossum
(Monodelphis domestica)
Mammalia -- 35
  • 26 (a)
OneToOne
tropical clawed frog
(Silurana tropicalis)
Amphibia LOC100496911 34
  • 54.53 (n)
zebrafish
(Danio rerio)
Actinopterygii si:dkeyp-106c3.1 35
  • 14 (a)
OneToOne
LOC101882735 34
Species where no ortholog for LOC400499 was found in the sources mined by GeneCards:
  • A. gosspyii yeast (Ashbya gossypii)
  • Actinobacteria (Mycobacterium tuberculosis)
  • African clawed frog (Xenopus laevis)
  • African malaria mosquito (Anopheles gambiae)
  • Alicante grape (Vitis vinifera)
  • alpha proteobacteria (Wolbachia pipientis)
  • amoeba (Dictyostelium discoideum)
  • Archea (Pyrococcus horikoshii)
  • baker's yeast (Saccharomyces cerevisiae)
  • barley (Hordeum vulgare)
  • beta proteobacteria (Neisseria meningitidis)
  • bread mold (Neurospora crassa)
  • chicken (Gallus gallus)
  • Chromalveolata (Phytophthora infestans)
  • common water flea (Daphnia pulex)
  • corn (Zea mays)
  • E. coli (Escherichia coli)
  • filamentous fungi (Aspergillus nidulans)
  • Firmicute bacteria (Streptococcus pneumoniae)
  • fission yeast (Schizosaccharomyces pombe)
  • fruit fly (Drosophila melanogaster)
  • green algae (Chlamydomonas reinhardtii)
  • honey bee (Apis mellifera)
  • K. lactis yeast (Kluyveromyces lactis)
  • lizard (Anolis carolinensis)
  • loblloly pine (Pinus taeda)
  • malaria parasite (Plasmodium falciparum)
  • medicago trunc (Medicago Truncatula)
  • moss (Physcomitrella patens)
  • mouse (Mus musculus)
  • orangutan (Pongo pygmaeus)
  • pig (Sus scrofa)
  • rainbow trout (Oncorhynchus mykiss)
  • rat (Rattus norvegicus)
  • rice (Oryza sativa)
  • rice blast fungus (Magnaporthe grisea)
  • schistosome parasite (Schistosoma mansoni)
  • sea anemone (Nematostella vectensis)
  • sea squirt (Ciona intestinalis)
  • sea squirt (Ciona savignyi)
  • sea urchin (Strongylocentrotus purpuratus)
  • sorghum (Sorghum bicolor)
  • soybean (Glycine max)
  • stem rust fungus (Puccinia graminis)
  • sugarcane (Saccharum officinarum)
  • thale cress (Arabidopsis thaliana)
  • tomato (Lycopersicon esculentum)
  • toxoplasmosis (Toxoplasma gondii)
  • Trichoplax (Trichoplax adhaerens)
  • wheat (Triticum aestivum)
  • worm (Caenorhabditis elegans)

Evolution for LOC400499 Gene

ENSEMBL:
Gene Tree for LOC400499 (if available)
TreeFam:
Gene Tree for LOC400499 (if available)

Paralogs for LOC400499 Gene

No data available for Paralogs for LOC400499 Gene

Variants for LOC400499 Gene

Sequence variations from dbSNP and Humsavar for LOC400499 Gene

SNP ID Clin Chr 16 pos Variation AA Info Type
rs1000006360 -- 11,412,608(-) C/A/T downstream_transcript_variant, genic_downstream_transcript_variant, intron_variant
rs1000009588 -- 11,383,485(-) C/T genic_downstream_transcript_variant, intron_variant
rs1000019351 -- 11,511,657(-) T/G genic_upstream_transcript_variant, intron_variant
rs1000033877 -- 11,449,783(-) G/A/C intron_variant
rs1000034551 -- 11,513,324(-) G/T genic_upstream_transcript_variant, intron_variant

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for LOC400499 Gene

Disorders for LOC400499 Gene

Additional Disease Information for LOC400499

Genetic Association Database
(GAD)

No disorders were found for LOC400499 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot and Genatlas for LOC400499 Gene

Publications for LOC400499 Gene

  1. A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome. (PMID: 28065597) Yao Z … Stagljar I (Molecular cell 2017) 3 58
  2. The sequence and analysis of duplication-rich human chromosome 16. (PMID: 15616553) Martin J … Pennacchio LA (Nature 2004) 13 58

No data available for External Links for LOC400499 Gene

Products for LOC400499 Gene

Sources for LOC400499 Gene

Content
Loading form....