This genomic region represents a DNase I hypersensitive site (DHS) that was predicted to be an enhancer by the ENCODE (ENCyclopedia Of DNA Elements) project based on various combinations of H3K27 acetylation and binding of p300, GATA1 and RNA polymerase II in K562 erythroleukemia cells. It was validated as a high-confidence cis-regulatory element for the H2BC11 (H2B clustered h... See more...

Aliases for LOC116183047 Gene

Aliases for LOC116183047 Gene

  • CRISPRi-Validated Cis-Regulatory Element Chr6.1269 3

External Ids for LOC116183047 Gene

Previous GeneCards Identifiers for LOC116183047 Gene

  • GC06U903833

Summaries for LOC116183047 Gene

Entrez Gene Summary for LOC116183047 Gene

  • This genomic region represents a DNase I hypersensitive site (DHS) that was predicted to be an enhancer by the ENCODE (ENCyclopedia Of DNA Elements) project based on various combinations of H3K27 acetylation and binding of p300, GATA1 and RNA polymerase II in K562 erythroleukemia cells. It was validated as a high-confidence cis-regulatory element for the H2BC11 (H2B clustered histone 11) gene on chromosome 6, and with lower confidence for the H2BC12 (H2B clustered histone 12) gene, based on multiplex CRISPR/Cas9-mediated perturbation in K562 cells. [provided by RefSeq, Oct 2019]

GeneCards Summary for LOC116183047 Gene

LOC116183047 (CRISPRi-Validated Cis-Regulatory Element Chr6.1269) is a Biological Region gene.

Additional gene information for LOC116183047 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for LOC116183047 Gene

Genomics for LOC116183047 Gene

Genomic Locations for LOC116183047 Gene

Genomic Locations for LOC116183047 Gene
chr6:27,600,519-27,600,691
(GRCh38/hg38)
Size:
173 bases
Orientation:
Plus strand

Genomic View for LOC116183047 Gene

Genes around LOC116183047 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LOC116183047 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LOC116183047 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LOC116183047 Gene

No data available for GeneHancer (GH) Regulatory Elements for LOC116183047 Gene

Proteins for LOC116183047 Gene

Post-translational modifications for LOC116183047 Gene

No Post-translational modifications

No data available for DME Specific Peptides for LOC116183047 Gene

Domains & Families for LOC116183047 Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for LOC116183047 Gene

Function for LOC116183047 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LOC116183047 Gene

Localization for LOC116183047 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LOC116183047 Gene

Pathways & Interactions for LOC116183047 Gene

PathCards logo

SuperPathways for LOC116183047 Gene

No Data Available

Gene Ontology (GO) - Biological Process for LOC116183047 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for LOC116183047 Gene

Drugs & Compounds for LOC116183047 Gene

No Compound Related Data Available

Transcripts for LOC116183047 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for LOC116183047 Gene

No ASD Table

Relevant External Links for LOC116183047 Gene

GeneLoc Exon Structure for
LOC116183047

No data available for mRNA/cDNA for LOC116183047 Gene

Expression for LOC116183047 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LOC116183047 Gene

Orthologs for LOC116183047 Gene

No data available for Orthologs and Evolution for LOC116183047 Gene

Paralogs for LOC116183047 Gene

No data available for Paralogs for LOC116183047 Gene

Variants for LOC116183047 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for LOC116183047 Gene

Disorders for LOC116183047 Gene

No disorders were found for LOC116183047 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for LOC116183047 Gene

Publications for LOC116183047 Gene

  1. A Genome-wide Framework for Mapping Gene Regulation via Cellular Genetic Screens. (PMID: 30612741) Gasperini M … Shendure J (Cell 2019) 3
  2. An integrated encyclopedia of DNA elements in the human genome. (PMID: 22955616) ENCODE Project Consortium (Nature 2012) 3
  3. The accessible chromatin landscape of the human genome. (PMID: 22955617) Thurman RE … Stamatoyannopoulos JA (Nature 2012) 3

No data available for Mastermind for LOC116183047 Gene

Products for LOC116183047 Gene

Sources for LOC116183047 Gene