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Aliases for LOC114255744 Gene

Aliases for LOC114255744 Gene

  • ZRS Shadow Enhancer 3
  • SZRS 3

External Ids for LOC114255744 Gene

Summaries for LOC114255744 Gene

Entrez Gene Summary for LOC114255744 Gene

  • This genomic region, which is located in an intron of the limb development membrane protein 1 (LMBR1) gene, can activate a minimal gata2 promoter in the zone of polarizing activity (ZPA) domain of developing fins in transgenic zebrafish. It is thought to be a shadow enhancer of the ZPA regulatory sequence (ZRS), which is also in the same LMBR1 intron and which regulates expression of the sonic hedgehog signaling molecule (SHH) gene during human limb development. Deletions of both the orthologous ZRS and shadow ZRS (sZRS) enhancers in the medaka genome suggest that both enhancer regions are necessary for sonic hedgehog gene expression and pectoral fin development. [provided by RefSeq, Feb 2019]

GeneCards Summary for LOC114255744 Gene

LOC114255744 (ZRS Shadow Enhancer) is a Biological Region gene.

Additional gene information for LOC114255744 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LOC114255744 Gene

Genomics for LOC114255744 Gene

Genomic Locations for LOC114255744 Gene

Genomic Locations for LOC114255744 Gene
chr7:-
(GRCh38/hg38)
Orientation:
Unknown strand

Genomic View for LOC114255744 Gene


Cytogenetic band:
GeneLoc Logo Gene Density

No data available for GeneHancer (GH) Regulatory Elements and RefSeq DNA sequence for LOC114255744 Gene

Proteins for LOC114255744 Gene

Post-translational modifications for LOC114255744 Gene

No Post-translational modifications

No data available for DME Specific Peptides for LOC114255744 Gene

Domains & Families for LOC114255744 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for LOC114255744 Gene

Function for LOC114255744 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LOC114255744 Gene

Localization for LOC114255744 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LOC114255744 Gene

Pathways & Interactions for LOC114255744 Gene

PathCards logo

SuperPathways for LOC114255744 Gene

No Data Available

Interacting Proteins for LOC114255744 Gene

Gene Ontology (GO) - Biological Process for LOC114255744 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for LOC114255744 Gene

Drugs & Compounds for LOC114255744 Gene

No Compound Related Data Available

Transcripts for LOC114255744 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for LOC114255744 Gene

No ASD Table

No data available for mRNA/cDNA for LOC114255744 Gene

Expression for LOC114255744 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LOC114255744 Gene

Orthologs for LOC114255744 Gene

No data available for Orthologs and Evolution for LOC114255744 Gene

Paralogs for LOC114255744 Gene

No data available for Paralogs for LOC114255744 Gene

Variants for LOC114255744 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for LOC114255744 Gene

Disorders for LOC114255744 Gene

No disorders were found for LOC114255744 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for LOC114255744 Gene

Publications for LOC114255744 Gene

  1. A conserved Shh cis-regulatory module highlights a common developmental origin of unpaired and paired fins. (PMID: 29556077) Letelier J … Gómez-Skarmeta JL (Nature genetics 2018) 3 58
  2. Toward a complete human genome sequence. (PMID: 9847074) Sanger Center … Genome Sequencing Center (Genome research 1998) 3 58

No data available for External Links for LOC114255744 Gene

Products for LOC114255744 Gene

Sources for LOC114255744 Gene

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