Aliases for LOC112268484 Gene
External Ids for LOC112268484 Gene
- Entrez Gene: 112268484
This genomic sequence was predicted to be a transcriptional regulatory region based on chromatin state analysis from the ENCODE (ENCyclopedia Of DNA Elements) project. A subregion was validated as a functional enhancer by the Sharpr-MPRA technique (Systematic high-resolution activation and repression profiling with reporter tiling using massively parallel reporter assays) in both HepG2 liver carcinoma cells (group: HepG2 Activating DNase unmatched - State 1:Tss, active promoter, TSS/CpG island region) and K562 erythroleukemia cells (group: K562 Activating non-DNase unmatched - State 5:Enh, candidate strong enhancer, open chromatin). In addition, this genomic region was validated as a high-confidence cis-regulatory element for the LGALS3 (galectin 3) gene on chromosome 14 based on multiplex CRISPR/Cas9-mediated perturbation in K562 cells. [provided by RefSeq, Nov 2019]
GeneCards Summary for LOC112268484 Gene
LOC112268484 (Sharpr-MPRA Regulatory Region 8345) is a Biological Region gene.