Aliases for LOC111828517 Gene
External Ids for LOC111828517 Gene
- Entrez Gene: 111828517
This genomic sequence, which overlaps the promoter and 5' region of the RAB28 (RAB28, member RAS oncogene family) gene on chromosome 4, was predicted to be a transcriptional regulatory region based on chromatin state analysis from the ENCODE (ENCyclopedia Of DNA Elements) project. It contains two overlapping sub-regions, one of which was validated as a functional enhancer by the Sharpr-MPRA technique (Systematic high-resolution activation and repression profiling with reporter tiling using massively parallel reporter assays) in both HepG2 liver carcinoma cells (group: HepG2 Activating DNase matched - State 1:Tss, active promoter, TSS/CpG island region) and K562 erythroleukemia cells (group: K562 Activating non-DNase unmatched - State 1:Tss). The other sub-region displayed weak repressive activity by Sharpr-MPRA in K562 cells (group: K562 Repressive DNase matched - State 1:Tss). [provided by RefSeq, Jan 2018]
GeneCards Summary for LOC111828517 Gene
LOC111828517 (Sharpr-MPRA Regulatory Regions 1971 And 3941) is a Biological Region gene.