This genomic region was predicted to be a cell type-specific enhancer based on chromatin state analysis from the ENCODE (ENCyclopedia Of DNA Elements) project. It was validated as a functional enhancer by high-throughput massively parallel reporter assays (MPRAs) in K562 erythroleukemia cells. This enhancer contains a motif for a GATA activator. Mutation of this motif results i... See more...

Aliases for LOC111591502 Gene

Aliases for LOC111591502 Gene

  • GATA Motif-Containing MPRA Enhancer 275 3
  • Massively Parallel Reporter Assay Enhancer 275 3
  • GATA Activator MPRA Enhancer 275 3

External Ids for LOC111591502 Gene

Summaries for LOC111591502 Gene

Entrez Gene Summary for LOC111591502 Gene

  • This genomic region was predicted to be a cell type-specific enhancer based on chromatin state analysis from the ENCODE (ENCyclopedia Of DNA Elements) project. It was validated as a functional enhancer by high-throughput massively parallel reporter assays (MPRAs) in K562 erythroleukemia cells. This enhancer contains a motif for a GATA activator. Mutation of this motif results in reduced enhancer activity. [provided by RefSeq, Dec 2017]

GeneCards Summary for LOC111591502 Gene

LOC111591502 (GATA Motif-Containing MPRA Enhancer 275) is a Biological Region gene.

Additional gene information for LOC111591502 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for LOC111591502 Gene

Genomics for LOC111591502 Gene

Genomic Locations for LOC111591502 Gene

Genomic Locations for LOC111591502 Gene
chr7:-
(GRCh38/hg38)
Orientation:
Unknown strand

Genomic View for LOC111591502 Gene


Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for LOC111591502 Gene

No data available for GeneHancer (GH) Regulatory Elements for LOC111591502 Gene

Proteins for LOC111591502 Gene

Post-translational modifications for LOC111591502 Gene

No Post-translational modifications

No data available for DME Specific Peptides for LOC111591502 Gene

Domains & Families for LOC111591502 Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for LOC111591502 Gene

Function for LOC111591502 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LOC111591502 Gene

Localization for LOC111591502 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LOC111591502 Gene

Pathways & Interactions for LOC111591502 Gene

PathCards logo

SuperPathways for LOC111591502 Gene

No Data Available
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Gene Ontology (GO) - Biological Process for LOC111591502 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for LOC111591502 Gene

Drugs & Compounds for LOC111591502 Gene

No Compound Related Data Available

Transcripts for LOC111591502 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for LOC111591502 Gene

No ASD Table

No data available for mRNA/cDNA for LOC111591502 Gene

Expression for LOC111591502 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LOC111591502 Gene

Orthologs for LOC111591502 Gene

No data available for Orthologs and Evolution for LOC111591502 Gene

Paralogs for LOC111591502 Gene

No data available for Paralogs for LOC111591502 Gene

Variants for LOC111591502 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for LOC111591502 Gene

Disorders for LOC111591502 Gene

No disorders were found for LOC111591502 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for LOC111591502 Gene

Publications for LOC111591502 Gene

  1. Systematic dissection of regulatory motifs in 2000 predicted human enhancers using a massively parallel reporter assay. (PMID: 23512712) Kheradpour P … Kellis M (Genome research 2013) 3 54
  2. Mapping and analysis of chromatin state dynamics in nine human cell types. (PMID: 21441907) Ernst J … Bernstein BE (Nature 2011) 3 54
  3. Toward a complete human genome sequence. (PMID: 9847074) Sanger Center … Genome Sequencing Center (Genome research 1998) 3 54

No data available for Mastermind for LOC111591502 Gene

Products for LOC111591502 Gene

Sources for LOC111591502 Gene