Aliases for LOC111429620 Gene
External Ids for LOC111429620 Gene
- Entrez Gene: 111429620
This genomic region was predicted to be a cell type-specific enhancer based on chromatin state analysis from the ENCODE (ENCyclopedia Of DNA Elements) project. A subregion was validated as a functional enhancer by high-throughput massively parallel reporter assays (MPRAs) in K562 erythroleukemia cells. The enhancer contains a conserved motif for a GATA activator, and mutation of the motif results in reduced enhancer activity. In addition, this genomic region was validated as a high-confidence cis-regulatory element for the RHAG (Rh associated glycoprotein) gene on chromosome 6 based on multiplex CRISPR/Cas9-mediated perturbation in K562 cells. [provided by RefSeq, Oct 2019]
GeneCards Summary for LOC111429620 Gene
LOC111429620 (GATA Motif-Containing MPRA Enhancer 217) is a Biological Region gene.