Aliases for LOC111258501 Gene
External Ids for LOC111258501 Gene
- Entrez Gene: 111258501
This region represents the promoter and a nearby upstream enhancer of the Meis homeobox 1 gene. Both the promoter and enhancer correspond to DNase I hypersensitive sites. The promoter region can act as an enhancer on a heterologous promoter and drive expression of a transgene in the developing nervous system. Activity of this sequence is induced by association of Spi-1 proto-oncogene and E74 like ETS transcription factor 1. This region has been found to be epigenetically silenced by DNA methylation in tumor cells. [provided by RefSeq, Oct 2017]
GeneCards Summary for LOC111258501 Gene
LOC111258501 (MEIS1 5' Regulatory Region) is a Biological Region gene.