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Aliases for LOC110599591 Gene

Aliases for LOC110599591 Gene

  • CYP3A7 5' Regulatory Region 3
  • CYP3A7 Promoter 3

External Ids for LOC110599591 Gene

Summaries for LOC110599591 Gene

Entrez Gene Summary for LOC110599591 Gene

  • This region represents the 5' regulatory region of cytochrome P450 family 3 subfamily A member 7 (CYP3A7), and includes both the proximal promoter and associated distal regulatory elements, including an upstream xenobiotic responsive module. This region is activated by xenobiotics and glucocorticoids, and is stimulated by binding of forkhead box A2, Sp1/Sp3 transcription factors, upstream transcription factor 1, nuclear receptor subfamily 1 group I members, and nuclear factor I to the proximal promoter. The 5' regulatory regions of CYP3 family members, including CYP3A4 and CYP3A5, are highly similar at the sequence level but have subtle differences in function. [provided by RefSeq, Jul 2017]

GeneCards Summary for LOC110599591 Gene

LOC110599591 (CYP3A7 5' Regulatory Region) is a Biological Region gene.

Additional gene information for LOC110599591 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LOC110599591 Gene

Genomics for LOC110599591 Gene

Genomic Locations for LOC110599591 Gene

Genomic Locations for LOC110599591 Gene
chr7:-
(GRCh38/hg38)
Orientation:
Unknown strand

Genomic View for LOC110599591 Gene

RefSeq DNA sequence for LOC110599591 Gene

No data available for GeneHancer (GH) Regulatory Elements and Cytogenetic band for LOC110599591 Gene

Proteins for LOC110599591 Gene

Post-translational modifications for LOC110599591 Gene

No Post-translational modifications

No data available for DME Specific Peptides for LOC110599591 Gene

Domains & Families for LOC110599591 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for LOC110599591 Gene

Function for LOC110599591 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LOC110599591 Gene

Localization for LOC110599591 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LOC110599591 Gene

Pathways & Interactions for LOC110599591 Gene

PathCards logo

SuperPathways for LOC110599591 Gene

No Data Available

Interacting Proteins for LOC110599591 Gene

Gene Ontology (GO) - Biological Process for LOC110599591 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for LOC110599591 Gene

Drugs & Compounds for LOC110599591 Gene

No Compound Related Data Available

Transcripts for LOC110599591 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for LOC110599591 Gene

No ASD Table

No data available for mRNA/cDNA for LOC110599591 Gene

Expression for LOC110599591 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LOC110599591 Gene

Orthologs for LOC110599591 Gene

No data available for Orthologs and Evolution for LOC110599591 Gene

Paralogs for LOC110599591 Gene

No data available for Paralogs for LOC110599591 Gene

Variants for LOC110599591 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for LOC110599591 Gene

Disorders for LOC110599591 Gene

No disorders were found for LOC110599591 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for LOC110599591 Gene

Publications for LOC110599591 Gene

  1. Dynamics of Cytosine Methylation in the Proximal Promoters of CYP3A4 and CYP3A7 in Pediatric and Prenatal Livers. (PMID: 26772622) Vyhlidal CA … Leeder JS (Drug metabolism and disposition: the biological fate of chemicals 2016) 3 58
  2. Expression and regulation of human fetal-specific CYP3A7 in mice. (PMID: 22253426) Pang XY … Gonzalez FJ (Endocrinology 2012) 3 58
  3. Effects of hypoxia-inducible factor-1α chemical stabilizer, CoCl(2) and hypoxia on gene expression of CYP3As in human fetal liver cells. (PMID: 22277676) Suzuki E … Ohmori S (Drug metabolism and pharmacokinetics 2012) 3 58
  4. Regulation of the CYP3A4 and CYP3A7 promoters by members of the nuclear factor I transcription factor family. (PMID: 19706729) Riffel AK … Vyhlidal CA (Molecular pharmacology 2009) 3 58
  5. A double transgenic mouse model expressing human pregnane X receptor and cytochrome P450 3A4. (PMID: 18799805) Ma X … Gonzalez FJ (Drug metabolism and disposition: the biological fate of chemicals 2008) 3 58

No data available for External Links for LOC110599591 Gene

Products for LOC110599591 Gene

Sources for LOC110599591 Gene

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