Aliases for LOC110599569 Gene
- CYP2C9 Promoter 3
External Ids for LOC110599569 Gene
- Entrez Gene: 110599569
This region represents the promoter of the cytochrome P450 family 2 subfamily C member 9 (CYP2C9) gene. Activity of this promoter is induced by xenobiotics, vitamin D, estrogens, and glucocorticoids. Hepatocyte nuclear factor 4 alpha, nuclear receptor subfamily 1 group I family members, and GATA binding proteins recognize discrete sites in this sequence to promote transcription. Fos and JunD proto-oncogenes bind to two different AP-1 motifs, which may then loop together, resulting in a formation of a positive regulatory complex. Naturally-occurring sequence variation in this region was found to influence promoter activity, possibly through disruption of transcription factor binding sites. [provided by RefSeq, Jul 2017]
GeneCards Summary for LOC110599569 Gene
LOC110599569 (CYP2C9 Promoter) is a Biological Region gene.