This region is found in the subtelomeric region of chromosome 16 on the p arm, and has been identified as a meiotic recombination hotspot by molecular assays in male germ cells. Meiotic hotspot activity can vary widely amongst individuals and is partly influenced by both the nucleotide sequence at the meiotic recombination hotspot and the specific alleles present at the PR doma... See more...

Aliases for LOC110596865 Gene

Aliases for LOC110596865 Gene

  • 16p Subtelomeric Meiotic Recombination Hotspot 3

External Ids for LOC110596865 Gene

Summaries for LOC110596865 Gene

Entrez Gene Summary for LOC110596865 Gene

  • This region is found in the subtelomeric region of chromosome 16 on the p arm, and has been identified as a meiotic recombination hotspot by molecular assays in male germ cells. Meiotic hotspot activity can vary widely amongst individuals and is partly influenced by both the nucleotide sequence at the meiotic recombination hotspot and the specific alleles present at the PR domain 9 (PRDM9) locus. [provided by RefSeq, Jul 2017]

GeneCards Summary for LOC110596865 Gene

LOC110596865 (16p Subtelomeric Meiotic Recombination Hotspot) is a Biological Region gene.

Additional gene information for LOC110596865 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for LOC110596865 Gene

Genomics for LOC110596865 Gene

Genomic Locations for LOC110596865 Gene

Genomic Locations for LOC110596865 Gene
chr16:-
(GRCh38/hg38)
Orientation:
Unknown strand

Genomic View for LOC110596865 Gene


Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for LOC110596865 Gene

No data available for GeneHancer (GH) Regulatory Elements for LOC110596865 Gene

Proteins for LOC110596865 Gene

Post-translational modifications for LOC110596865 Gene

No Post-translational modifications

No data available for DME Specific Peptides for LOC110596865 Gene

Domains & Families for LOC110596865 Gene

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for LOC110596865 Gene

Function for LOC110596865 Gene

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LOC110596865 Gene

Localization for LOC110596865 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LOC110596865 Gene

Pathways & Interactions for LOC110596865 Gene

PathCards logo

SuperPathways for LOC110596865 Gene

No Data Available
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Gene Ontology (GO) - Biological Process for LOC110596865 Gene

None

No data available for Pathways by source , Interacting Proteins and SIGNOR curated interactions for LOC110596865 Gene

Drugs & Compounds for LOC110596865 Gene

No Compound Related Data Available

Transcripts for LOC110596865 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for LOC110596865 Gene

No ASD Table

No data available for mRNA/cDNA for LOC110596865 Gene

Expression for LOC110596865 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LOC110596865 Gene

Orthologs for LOC110596865 Gene

No data available for Orthologs and Evolution for LOC110596865 Gene

Paralogs for LOC110596865 Gene

No data available for Paralogs for LOC110596865 Gene

Variants for LOC110596865 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations, with clinical significance, from ClinVar and Humsavar, with links to dbSNP , Additional dbSNP identifiers (rs#s) , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for LOC110596865 Gene

Disorders for LOC110596865 Gene

No disorders were found for LOC110596865 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for LOC110596865 Gene

Publications for LOC110596865 Gene

  1. DNA recombination. Recombination initiation maps of individual human genomes. (PMID: 25395542) Pratto F … Camerini-Otero RD (Science (New York, N.Y.) 2014) 3 54
  2. Variants of the protein PRDM9 differentially regulate a set of human meiotic recombination hotspots highly active in African populations. (PMID: 21750151) Berg IL … Jeffreys AJ (Proceedings of the National Academy of Sciences of the United States of America 2011) 3 54
  3. A common sequence motif associated with recombination hot spots and genome instability in humans. (PMID: 19165926) Myers S … McVean G (Nature genetics 2008) 3 54
  4. Crossover breakpoint mapping identifies a subtelomeric hotspot for male meiotic recombination. (PMID: 10767349) Badge RM … Armour JA (Human molecular genetics 2000) 3 54

No data available for Mastermind for LOC110596865 Gene

Products for LOC110596865 Gene

Sources for LOC110596865 Gene