Aliases for LOC110121291 Gene
External Ids for LOC110121291 Gene
- Entrez Gene: 110121291
This genomic region represents a conserved exonic enhancer (eExon 19) that overlaps an exon of the HDAC9 (histone deacetylase 9) gene on the p arm of chromosome 7. It can activate a Hsp68 promoter coupled to a reporter gene in the posterior limb bud of transgenic mice, or an E1b promoter in pectoral fin and branchial arch of transgenic zebrafish. This eExon is thought to be a tissue-specific limb enhancer of the TWIST1 (twist family bHLH transcription factor 1) gene on the q arm of chromosome 7, where that gene encodes a transcription factor that inhibits the expression of the SHH (sonic hedgehog signaling molecule) gene in the anterior limb bud. [provided by RefSeq, Apr 2019]
GeneCards Summary for LOC110121291 Gene
LOC110121291 (EExon 19 TWIST1 Limb Enhancer) is a Biological Region gene.