This locus represents naturally occurring readthrough transcription between the neighboring genes LOC110117498 and PIK3R3. The readthrough transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Apr 2017] See more...

Aliases for LOC110117498-PIK3R3 Gene

Aliases for LOC110117498-PIK3R3 Gene

  • LOC110117498-PIK3R3 Readthrough 3
  • Uncharacterized Protein 13
  • -PIK3R3 Readthrough 5
  • AL358075.4 5

External Ids for LOC110117498-PIK3R3 Gene

Previous GeneCards Identifiers for LOC110117498-PIK3R3 Gene

  • GC01M046078
  • GC01M046081
  • GC01U905717
  • GC01M046065
  • GC01M046068
  • GC01M046071
  • GC01M046074

Summaries for LOC110117498-PIK3R3 Gene

Entrez Gene Summary for LOC110117498-PIK3R3 Gene

  • This locus represents naturally occurring readthrough transcription between the neighboring genes LOC110117498 and PIK3R3. The readthrough transcript encodes a fusion protein that shares sequence identity with each individual gene product. [provided by RefSeq, Apr 2017]

GeneCards Summary for LOC110117498-PIK3R3 Gene

LOC110117498-PIK3R3 (LOC110117498-PIK3R3 Readthrough) is a Protein Coding gene. An important paralog of this gene is PIK3R3.

Additional gene information for LOC110117498-PIK3R3 Gene

No data available for CIViC Summary , UniProtKB/Swiss-Prot Summary , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , Rfam classification and piRNA Summary for LOC110117498-PIK3R3 Gene

Genomics for LOC110117498-PIK3R3 Gene

GeneHancer (GH) Regulatory Elements for LOC110117498-PIK3R3 Gene

Promoters and enhancers for LOC110117498-PIK3R3 Gene
GeneHancer (GH) Identifier GH Type GH
Score
GH Sources Gene Association Score Total Score TSS distance (kb) Number of Genes Away Size (kb) Transcription Factor
Binding Sites
Gene Targets
GH01J046176 Promoter 0.4 EPDnew 750.6 0.0 -20 0.1 PRDM10 LOC110117498-PIK3R3 P3R3URF PIK3R3 TSPAN1 lnc-POMGNT1-1 lnc-PIK3R3-3
GH01J046177 Enhancer 0.3 Ensembl 750.6 +0.2 187 0.2 PRDM10 LOC110117498-PIK3R3 P3R3URF PIK3R3 TSPAN1 lnc-POMGNT1-1
GH01J046170 Promoter/Enhancer 1.8 EPDnew FANTOM5 Ensembl ENCODE dbSUPER 0.6 +3.2 3160 5 SREBF1 SMARCE1 POLR2A CC2D1A HLF MNT ZNF148 ZNF473 CEBPG SP7 TSPAN1 NASP NSUN4 LRRC41 TOE1 TEX38 LURAP1 ENSG00000234329 RPS15AP10 CCDC163
GH01J046128 Promoter/Enhancer 2.3 EPDnew Ensembl ENCODE CraniofacialAtlas 0.3 +44.4 44435 8.1 ZNF785 ZNF24 ZBTB40 SREBF1 SIX5 ZBTB6 MLX SMARCE1 RBPJ POLR2A PIK3R3 LOC101929626 TOE1 LRRC41 GPBP1L1 ENSG00000234329 MUTYH EFCAB14-AS1 RPS15AP10 NASP
GH01J046166 Enhancer 0.7 FANTOM5 ENCODE dbSUPER 0.4 +9.5 9496 1.3 ELF1 NR2F2 ZBTB33 ENSG00000226957 TSPAN1 LOC110117498-PIK3R3 PIK3R3 FJ601666-003
- Elite GeneHancer and/or Elite GeneHancer-gene association Download GeneHancer data from 2017 publication | Request up-to-date GeneHancer data (full dataset)

GeneHancers around LOC110117498-PIK3R3 on UCSC Golden Path with GeneCards custom track

Genomic Locations for LOC110117498-PIK3R3 Gene

Genomic Locations for LOC110117498-PIK3R3 Gene
chr1:46,043,661-46,176,488
(GRCh38/hg38)
Size:
132,828 bases
Orientation:
Minus strand

Genomic View for LOC110117498-PIK3R3 Gene

Genes around LOC110117498-PIK3R3 on UCSC Golden Path with GeneCards custom track

Cytogenetic band:
LOC110117498-PIK3R3 Gene in genomic location: bands according to Ensembl, locations according to GeneLoc (and/or Entrez Gene and/or Ensembl if different)
Genomic Location for LOC110117498-PIK3R3 Gene
GeneLoc Logo Genomic Neighborhood Exon StructureGene Density

RefSeq DNA sequence for LOC110117498-PIK3R3 Gene

Proteins for LOC110117498-PIK3R3 Gene

  • Protein details for LOC110117498-PIK3R3 Gene (UniProtKB/TrEMBL)

    Protein Symbol:
    F6TDL0-F6TDL0_HUMAN
    Recommended name:
    Uncharacterized protein
    Protein Accession:
    F6TDL0

    Protein attributes for LOC110117498-PIK3R3 Gene

    Size:
    507 amino acids
    Molecular mass:
    59394 Da
    Quaternary structure:
    No Data Available

neXtProt entry for LOC110117498-PIK3R3 Gene

Post-translational modifications for LOC110117498-PIK3R3 Gene

No Post-translational modifications

Other Protein References for LOC110117498-PIK3R3 Gene

ENSEMBL proteins:
REFSEQ proteins:

No data available for DME Specific Peptides for LOC110117498-PIK3R3 Gene

Domains & Families for LOC110117498-PIK3R3 Gene

Protein Domains for LOC110117498-PIK3R3 Gene

genes like me logo Genes that share domains with LOC110117498-PIK3R3: view

No data available for Gene Families , Suggested Antigen Peptide Sequences , Graphical View of Domain Structure and UniProtKB/Swiss-Prot for LOC110117498-PIK3R3 Gene

Function for LOC110117498-PIK3R3 Gene

Phenotypes From GWAS Catalog for LOC110117498-PIK3R3 Gene

Gene Ontology (GO) - Molecular Function for LOC110117498-PIK3R3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0046935 1-phosphatidylinositol-3-kinase regulator activity IBA --
genes like me logo Genes that share ontologies with LOC110117498-PIK3R3: view

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LOC110117498-PIK3R3 Gene

Localization for LOC110117498-PIK3R3 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LOC110117498-PIK3R3 Gene

Pathways & Interactions for LOC110117498-PIK3R3 Gene

PathCards logo

SuperPathways for LOC110117498-PIK3R3 Gene

No Data Available

Interacting Proteins for LOC110117498-PIK3R3 Gene

STRING Interaction Network Preview (showing top 5 STRING interactants - click image to see top 25)
STRING Interaction Network
Selected Interacting proteins: ENSP00000439913 for LOC110117498-PIK3R3 Gene via STRING

GPS-Prot Interaction Network for LOC110117498-PIK3R3

Gene Ontology (GO) - Biological Process for LOC110117498-PIK3R3 Gene

GO ID Qualified GO term Evidence PubMed IDs
GO:0008286 insulin receptor signaling pathway IBA --
GO:0043551 regulation of phosphatidylinositol 3-kinase activity IBA --
GO:0046854 phosphatidylinositol phosphorylation IBA --
genes like me logo Genes that share ontologies with LOC110117498-PIK3R3: view

No data available for Pathways by source and SIGNOR curated interactions for LOC110117498-PIK3R3 Gene

Drugs & Compounds for LOC110117498-PIK3R3 Gene

No Compound Related Data Available

Transcripts for LOC110117498-PIK3R3 Gene

mRNA/cDNA for LOC110117498-PIK3R3 Gene

(1) REFSEQ mRNAs :
(3) Additional mRNA sequences :
(1) Ensembl transcripts including schematic representations, and UCSC links to gene/alias where relevant :

Alternative Splicing Database (ASD) splice patterns (SP) for LOC110117498-PIK3R3 Gene

No ASD Table

Relevant External Links for LOC110117498-PIK3R3 Gene

GeneLoc Exon Structure for
LOC110117498-PIK3R3

Expression for LOC110117498-PIK3R3 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LOC110117498-PIK3R3 Gene

Orthologs for LOC110117498-PIK3R3 Gene

Evolution for LOC110117498-PIK3R3 Gene

ENSEMBL:
Gene Tree for LOC110117498-PIK3R3 (if available)
TreeFam:
Gene Tree for LOC110117498-PIK3R3 (if available)

No data available for Orthologs for LOC110117498-PIK3R3 Gene

Paralogs for LOC110117498-PIK3R3 Gene

Paralogs for LOC110117498-PIK3R3 Gene

genes like me logo Genes that share paralogs with LOC110117498-PIK3R3: view

Variants for LOC110117498-PIK3R3 Gene

Sequence variations from dbSNP and Humsavar for LOC110117498-PIK3R3 Gene

SNP ID Clin Chr 01 pos Variation AA Info Type
rs765790132 uncertain-significance, Familial cancer of breast 46,055,939(-) C/T coding_sequence_variant, missense_variant
rs1000001784 -- 46,064,396(-) C/G/T intron_variant
rs1000011558 -- 46,127,768(-) C/A intron_variant
rs1000014672 -- 46,131,119(-) T/G intron_variant
rs1000050297 -- 46,062,929(-) G/C intron_variant

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for LOC110117498-PIK3R3 Gene

Disorders for LOC110117498-PIK3R3 Gene

No disorders were found for LOC110117498-PIK3R3 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for LOC110117498-PIK3R3 Gene

Publications for LOC110117498-PIK3R3 Gene

  1. Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes. (PMID: 16344560) Kimura K … Sugano S (Genome research 2006) 3 56
  2. The DNA sequence and biological annotation of human chromosome 1. (PMID: 16710414) Gregory SG … Prigmore E (Nature 2006) 13 56

Products for LOC110117498-PIK3R3 Gene

Sources for LOC110117498-PIK3R3 Gene