Aliases for LOC110006317 Gene
External Ids for LOC110006317 Gene
- Entrez Gene: 110006317
This biological region is found within an intron of the serine/threonine kinase 11 (STK11) gene, and is known to undergo Alu-repeat-mediated non-allelic homologous recombination (NAHR) with the serine/threonine kinase 11 intron 3 recombination region, located about 7 kb centromere-proximal to this region on the reference genome. Recombination between these regions can result in deletion of the intervening sequences. Deletion of a portion of the serine/threonine kinase 11 gene is one cause of Peutz-Jeghers syndrome, an autosomal dominant condition. Other deletions, rearrangements, and mutations have been shown to be causative for Peutz-Jeghers syndrome, but are not represented in this region. This region represents only the recurrent recombination event that occurs with the serine/threonine kinase 11 intron 3 recombination region. [provided by RefSeq, Mar 2017]
GeneCards Summary for LOC110006317 Gene
LOC110006317 (Serine/Threonine Kinase 11 Intron 1 Alu-Mediated Recombination Region) is a Biological Region gene. Diseases associated with LOC110006317 include Peutz-Jeghers Syndrome.