Aliases for LOC109286555 Gene
External Ids for LOC109286555 Gene
- Entrez Gene: 109286555
This biological region overlaps the chromosome 11 open reading frame 80 (C11orf80) gene on the q arm of chromosome 11, and contains a CGG/CCG trinucleotide repeat. Somatic variability at this locus has been observed, and expansions of this repeat cause fragility at this folate-sensitive fragile site. Expansions resulting in repeats with a copy number of up to 500 have been observed. Experiments suggest that expansion of the trinucleotide repeat may cause hypermethylation of the DNA in this region, and may be associated with reduced expression of the C11orf80 gene product. [provided by RefSeq, Dec 2016]
GeneCards Summary for LOC109286555 Gene
LOC109286555 (FRA11A Repeat Instability Region) is a Biological Region gene.