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Aliases for LOC109286555 Gene

Aliases for LOC109286555 Gene

  • FRA11A Repeat Instability Region 3
  • Fragile Site, Folic Acid Type, Rare, Fra(11)(Q13.3) Repeat Instability Region 3
  • C110rf80 Repeat Instability Region 3

External Ids for LOC109286555 Gene

Summaries for LOC109286555 Gene

Entrez Gene Summary for LOC109286555 Gene

  • This biological region overlaps the chromosome 11 open reading frame 80 (C11orf80) gene on the q arm of chromosome 11, and contains a CGG/CCG trinucleotide repeat. Somatic variability at this locus has been observed, and expansions of this repeat cause fragility at this folate-sensitive fragile site. Expansions resulting in repeats with a copy number of up to 500 have been observed. Experiments suggest that expansion of the trinucleotide repeat may cause hypermethylation of the DNA in this region, and may be associated with reduced expression of the C11orf80 gene product. [provided by RefSeq, Dec 2016]

GeneCards Summary for LOC109286555 Gene

LOC109286555 (FRA11A Repeat Instability Region) is a Biological Region gene.

Additional gene information for LOC109286555 Gene

No data available for CIViC summary , UniProtKB/Swiss-Prot , Tocris Summary , Gene Wiki entry , PharmGKB "VIP" Summary , fRNAdb sequence ontologies and piRNA Summary for LOC109286555 Gene

Genomics for LOC109286555 Gene

Genomic Locations for LOC109286555 Gene

Genomic Locations for LOC109286555 Gene
chr11:-
(GRCh38/hg38)
Orientation:
Unknown strand

Genomic View for LOC109286555 Gene


Cytogenetic band:
GeneLoc Logo Gene Density

RefSeq DNA sequence for LOC109286555 Gene

No data available for GeneHancer (GH) Regulatory Elements for LOC109286555 Gene

Proteins for LOC109286555 Gene

Post-translational modifications for LOC109286555 Gene

No Post-translational modifications

No data available for DME Specific Peptides for LOC109286555 Gene

Domains & Families for LOC109286555 Gene

Graphical View of Domain Structure for InterPro Entry

No data available for Gene Families , Protein Domains , Suggested Antigen Peptide Sequences and UniProtKB/Swiss-Prot for LOC109286555 Gene

Function for LOC109286555 Gene

Animal Model Products

No data available for Molecular function , Enzyme Numbers (IUBMB) , Phenotypes From GWAS Catalog , Gene Ontology (GO) - Molecular Function , Phenotypes , Human Phenotype Ontology , Animal Models , miRNA , Transcription Factor Targets and HOMER Transcription for LOC109286555 Gene

Localization for LOC109286555 Gene

No data available for Subcellular locations from UniProtKB/Swiss-Prot , Subcellular locations from COMPARTMENTS , Subcellular locations from the Human Protein Atlas (HPA) and Gene Ontology (GO) - Cellular Components for LOC109286555 Gene

Pathways & Interactions for LOC109286555 Gene

PathCards logo

SuperPathways for LOC109286555 Gene

No Data Available

Interacting Proteins for LOC109286555 Gene

Gene Ontology (GO) - Biological Process for LOC109286555 Gene

None

No data available for Pathways by source and SIGNOR curated interactions for LOC109286555 Gene

Drugs & Compounds for LOC109286555 Gene

No Compound Related Data Available

Transcripts for LOC109286555 Gene

Alternative Splicing Database (ASD) splice patterns (SP) for LOC109286555 Gene

No ASD Table

No data available for mRNA/cDNA for LOC109286555 Gene

Expression for LOC109286555 Gene

No Expression Related Data Available

No data available for mRNA expression in normal human tissues , mRNA expression in embryonic tissues and stem cells from LifeMap Discovery , mRNA differential expression in normal tissues , Protein differential expression in normal tissues , Protein expression , Protein tissue co-expression partners , mRNA Expression by UniProt/SwissProt , Evidence on tissue expression from TISSUES and Phenotype-based relationships between genes and organs from Gene ORGANizer for LOC109286555 Gene

Orthologs for LOC109286555 Gene

No data available for Orthologs and Evolution for LOC109286555 Gene

Paralogs for LOC109286555 Gene

No data available for Paralogs for LOC109286555 Gene

Variants for LOC109286555 Gene

No data available for Polymorphic Variants from UniProtKB/Swiss-Prot , Sequence variations from dbSNP and Humsavar , Structural Variations from Database of Genomic Variants (DGV) , Variation tolerance and Additional Variant Information for LOC109286555 Gene

Disorders for LOC109286555 Gene

No disorders were found for LOC109286555 Gene.

No data available for MalaCards , UniProtKB/Swiss-Prot , Genatlas and External Links for LOC109286555 Gene

Publications for LOC109286555 Gene

  1. Genome instability in the context of chromatin structure and fragile sites. (PMID: 21175410) Bartova E … Kozubek S (Critical reviews in eukaryotic gene expression 2010) 3 58
  2. Human chromosome fragility. (PMID: 18078840) Lukusa T … Fryns JP (Biochimica et biophysica acta 2008) 3 58
  3. The molecular basis of the folate-sensitive fragile site FRA11A at 11q13. (PMID: 18160775) Debacker K … Kooy F (Cytogenetic and genome research 2007) 3 58
  4. Fragile sites and minisatellite repeat instability. (PMID: 10873391) Handt O … Richards RI (Molecular genetics and metabolism 2000) 3 58
  5. Mapping FRA11A, a folate-sensitive fragile site in human chromosome band 11q13.3. (PMID: 9533019) Perucca-Lostanlen D … Gaudray P (Cytogenetics and cell genetics 1997) 3 58

No data available for External Links for LOC109286555 Gene

Products for LOC109286555 Gene

Sources for LOC109286555 Gene

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